Search Results - "Takayama, Shuichi"

Room Temperature Phosphorescence of Metal-Free Organic Materials in Amorphous Polymer Matrices by Lee, Dongwook, Bolton, Onas, Kim, Byoung Choul, Youk, Ji Ho, Takayama, Shuichi, Kim, Jinsang

“…Developing metal-free organic phosphorescent materials is promising but challenging because achieving emissive triplet relaxation that outcompetes the…”
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Dispersible hydrogel force sensors reveal patterns of solid mechanical stress in multicellular spheroid cultures by Lee, Wontae, Kalashnikov, Nikita, Mok, Stephanie, Halaoui, Ruba, Kuzmin, Elena, Putnam, Andrew J., Takayama, Shuichi, Park, Morag, McCaffrey, Luke, Zhao, Ruogang, Leask, Richard L., Moraes, Christopher

“…Understanding how forces orchestrate tissue formation requires technologies to map internal tissue stress at cellular length scales. Here, we develop ultrasoft…”
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Protocell arrays for simultaneous detection of diverse analytes by Zhang, Yan, Kojima, Taisuke, Kim, Ge-Ah, McNerney, Monica P., Takayama, Shuichi, Styczynski, Mark P.

“…Simultaneous detection of multiple analytes from a single sample (multiplexing), particularly when done at the point of need, can guide complex decision-making…”
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Organs-on-a-Chip: A Focus on Compartmentalized Microdevices by Moraes, Christopher, Mehta, Geeta, Lesher-Perez, Sasha Cai, Takayama, Shuichi

“…Advances in microengineering technologies have enabled a variety of insights into biomedical sciences that would not have been possible with conventional…”
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Formation and manipulation of cell spheroids using a density adjusted PEG/DEX aqueous two phase system by Han, Chungmin, Takayama, Shuichi, Park, Jaesung

“…Various spheroid formation techniques have been widely developed for efficient and reliable 3-D cell culture research. Although those efforts improved many…”
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High-throughput 3D spheroid culture and drug testing using a 384 hanging drop array by Tung, Yi-Chung, Hsiao, Amy Y, Allen, Steven G, Torisawa, Yu-suke, Ho, Mitchell, Takayama, Shuichi

“…Culture of cells as three-dimensional (3D) aggregates can enhance in vitro tests for basic biological research as well as for therapeutics development. Such 3D…”
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A reproducible scaffold-free 3D organoid model to study neoplastic progression in breast cancer by Djomehri, Sabra I., Burman, Boris, Gonzalez, Maria E., Takayama, Shuichi, Kleer, Celina G.

“…While 3D cellular models are useful to study biological processes, gel-embedded organoids have large variability. This paper describes high-yield production of…”
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High-throughput formation and image-based analysis of basal-in mammary organoids in 384-well plates by Lee, Soojung, Chang, Jonathan, Kang, Sung-Min, Parigoris, Eric, Lee, Ji-Hoon, Huh, Yun Suk, Takayama, Shuichi

“…This manuscript describes a new method for forming basal-in MCF10A organoids using commercial 384-well ultra-low attachment (ULA) microplates and the…”
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Budding-like division of all-aqueous emulsion droplets modulated by networks of protein nanofibrils by Song, Yang, Michaels, Thomas C. T., Ma, Qingming, Liu, Zhou, Yuan, Hao, Takayama, Shuichi, Knowles, Tuomas P. J., Shum, Ho Cheung

“…Networks of natural protein nanofibrils, such as cytoskeletal filaments, control the shape and the division of cells, yet mimicking this functionality in a…”
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Organ-on-a-chip and the kidney by Kim, Sejoong, Takayama, Shuichi

“…Abstract Traditional approaches to pathophysiology are advancing but still have many limitations that arise from real biologic systems and their associated…”
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Pumps for microfluidic cell culture by Byun, Chang Kyu, Abi-Samra, Kameel, Cho, Yoon-Kyoung, Takayama, Shuichi

“…In comparison to traditional in vitro cell culture in Petri dishes or well plates, cell culture in microfluidic‐based devices enables better control over…”
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Alginate Microencapsulation for Three-Dimensional In Vitro Cell Culture by Kang, Sung-Min, Lee, Ji-Hoon, Huh, Yun Suk, Takayama, Shuichi

“…Advances in microscale 3D cell culture systems have helped to elucidate cellular physiology, understand mechanisms of stem cell differentiation, produce…”
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Microscale Determination of Aqueous Two Phase System Binodals by Droplet Dehydration in Oil by Kojima, Taisuke, Takayama, Shuichi

“…This paper analyzes the use of a dehydrating oil system to determine binodal curves of an aqueous two phase system (ATPS). Aqueous droplets containing…”
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External Mechanical Cues Trigger the Establishment of the Anterior-Posterior Axis in Early Mouse Embryos by Hiramatsu, Ryuji, Matsuoka, Toshiki, Kimura-Yoshida, Chiharu, Han, Sung-Woong, Mochida, Kyoko, Adachi, Taiji, Takayama, Shuichi, Matsuo, Isao

“…Mouse anterior-posterior axis polarization is preceded by formation of the distal visceral endoderm (DVE) by unknown mechanisms. Here, we show by in vitro…”
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High-yield isolation of extracellular vesicles using aqueous two-phase system by Shin, Hyunwoo, Han, Chungmin, Labuz, Joseph M., Kim, Jiyoon, Kim, Jongmin, Cho, Siwoo, Gho, Yong Song, Takayama, Shuichi, Park, Jaesung

“…Extracellular vesicles (EVs) such as exosomes and microvesicles released from cells are potential biomarkers for blood-based diagnostic applications. To…”
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Formation of stable small cell number three-dimensional ovarian cancer spheroids using hanging drop arrays for preclinical drug sensitivity assays by Raghavan, Shreya, Ward, Maria R, Rowley, Katelyn R, Wold, Rachel M, Takayama, Shuichi, Buckanovich, Ronald J, Mehta, Geeta

“…Abstract Background Ovarian cancer grows and metastasizes from multicellular spheroidal aggregates within the ascites fluid. Multicellular tumor spheroids are…”
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Microanalysis using surface modification and biphasic droplets by Kojima, Taisuke, Takayama, Shuichi

“…Conventional methods for the synthesis and analysis of chemical and biological materials often utilize homogeneous bulk environments or surface immobilization…”
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Integrated elastomeric components for autonomous regulation of sequential and oscillatory flow switching in microfluidic devices by Torisawa, Yu-suke, Mosadegh, Bobak, Tung, Yi-Chung, Bersano-Begey, Tommaso, Kuo, Chuan-Hsien, Tavana, Hossein, Takayama, Shuichi

“…A critical need for enhancing the usability and capabilities of microfluidic technologies is the development of standardized, scalable and versatile control…”
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Acoustically detectable cellular-level lung injury induced by fluid mechanical stresses in microfluidic airway systems by Huh, Dongeun, Fujioka, Hideki, Tung, Yi-Chung, Futai, Nobuyuki, Paine, Robert III, Grotberg, James B, Takayama, Shuichi

“…We describe a microfabricated airway system integrated with computerized air-liquid two-phase microfluidics that enables on-chip engineering of human airway…”
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On being the right size: scaling effects in designing a human-on-a-chip by Moraes, Christopher, Labuz, Joseph M, Leung, Brendan M, Inoue, Mayumi, Chun, Tae-Hwa, Takayama, Shuichi

“…Developing a human-on-a-chip by connecting multiple model organ systems would provide an intermediate screen for therapeutic efficacy and toxic side effects of…”
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