Search Results - "Takayama, Hiromitsu"

Total Syntheses of Lycopodium and Monoterpenoid Indole Alkaloids Based on Biosynthesis-Inspired Strategies by Takayama, Hiromitsu

“…The merits of biogenetic considerations in the chemical syntheses of natural products have been emphasized by describing the total syntheses of Lycopodium…”
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Chemistry and Pharmacology of Analgesic Indole Alkaloids from the Rubiaceous Plant, Mitragyna speciosa by Takayama, Hiromitsu

“…The leaves of a tropical plant, Mitragyna speciosa KORTH (Rubiaceae), have been traditionally used as a substitute for opium. Phytochemical studies of the…”
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Total Syntheses of Pleiocarpamine, Normavacurine, and C‑Mavacurine by Sato, Keigo, Kogure, Noriyuki, Kitajima, Mariko, Takayama, Hiromitsu

“…The total syntheses of C-mavacurine-type indole alkaloids, (±)-pleiocarpamine, (±)-normavacurine, and (±)-C-mavacurine, were accomplished. The key step in the…”
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Asymmetric Total Synthesis of Fawcettimine-Type Lycopodium Alkaloid, Lycopoclavamine‑A by Kaneko, Hiroki, Takahashi, Shunsuke, Kogure, Noriyuki, Kitajima, Mariko, Takayama, Hiromitsu

“…An asymmetric total synthesis of lycopoclavamine-A (1), a structurally unique fawcettimine-type Lycopodium alkaloid, was achieved via a stereoselective…”
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Characterization of a recently evolved flavonol-phenylacyltransferase gene provides signatures of natural light selection in Brassicaceae by Tohge, Takayuki, Wendenburg, Regina, Ishihara, Hirofumi, Nakabayashi, Ryo, Watanabe, Mutsumi, Sulpice, Ronan, Hoefgen, Rainer, Takayama, Hiromitsu, Saito, Kazuki, Stitt, Mark, Fernie, Alisdair R.

“…Incidence of natural light stress renders it important to enhance our understanding of the mechanisms by which plants protect themselves from harmful effects…”
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Asymmetric Total Synthesis of a Pentacyclic Lycopodium Alkaloid: Huperzine-Q by Nakayama, Atsushi, Kogure, Noriyuki, Kitajima, Mariko, Takayama, Hiromitsu

“…Right on Q: The first asymmetric total synthesis of (−)‐huperzine‐Q, which possesses six stereogenic centers and a spiroaminal moiety, has been achieved in 19…”
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Asymmetric Total Synthesis of Sarpagine-Related Indole Alkaloids Hydroxygardnerine, Hydroxygardnutine, Gardnerine, (E)‑16-epi-Normacusine B, and Koumine by Kitajima, Mariko, Watanabe, Keisuke, Maeda, Hiroyuki, Kogure, Noriyuki, Takayama, Hiromitsu

“…Sarpagine-related indole alkaloids (−)-hydroxygardnerine, (+)-hydroxygardnutine, (−)-gardnerine, (+)-(E)-16-epi-normacusine B, and (−)-koumine were divergently…”
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Asymmetric Total Synthesis and Evaluation of Antitumor Activity of Ophiorrhisine A and Its Derivatives by Onozawa, Tadayoshi, Kitajima, Mariko, Kogure, Noriyuki, Takayama, Hiromitsu

“…The first asymmetric total synthesis of ophiorrhisine A (1), a new cyclic tetrapeptide isolated from Ophiorrhiza nutans, was accomplished via an intramolecular…”
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Asymmetric Total Synthesis and Structure Elucidation of Huperzine H by Shiomi, Shinya, Wilailak, Kaewsri, Soutome, Wataru, Takayama, Hiromitsu, Kitajima, Mariko, Ishikawa, Hayato

“…A first asymmetric total synthesis of huperzine H has been achieved in a 12% overall yield from commercially available (+)-pulegone. The key steps of this…”
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Biogenetically Inspired Total Syntheses of Lycopodium Alkaloids, (+)-Flabellidine and (−)-Lycodine by Azuma, Masayuki, Yoshikawa, Tetsuya, Kogure, Noriyuki, Kitajima, Mariko, Takayama, Hiromitsu

“…The first asymmetric total synthesis of (+)-flabellidine (2) and the shortest total synthesis of (−)-lycodine (3) were accomplished by a strategy featuring the…”
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flavonoid 3‐O‐glucoside:2″‐O‐glucosyltransferase responsible for terminal modification of pollen‐specific flavonols in Arabidopsis thaliana by Yonekura‐Sakakibara, Keiko, Nakabayashi, Ryo, Sugawara, Satoko, Tohge, Takayuki, Ito, Takuya, Koyanagi, Misuzu, Kitajima, Mariko, Takayama, Hiromitsu, Saito, Kazuki

“…Flavonol 3‐O‐diglucosides with a 1→2 inter‐glycosidic linkage are representative pollen‐specific flavonols that are widely distributed in plants, but their…”
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Concise asymmetric total synthesis of lycopodine and flabelliformine via cascade cyclization reaction by Wada, Kentaro, Kogure, Noriyuki, Kitajima, Mariko, Takayama, Hiromitsu

“…[Display omitted] •The shortest-step asymmetric total synthesis of lycopodine was accomplished.•The first asymmetric synthesis of flabelliformine was…”
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Total Synthesis Guided Structure Elucidation of (+)-Psychotetramine by Foo, Klement, Newhouse, Timothy, Mori, Ikue, Takayama, Hiromitsu, Baran, Phil S

“…Solving the puzzles: Total synthesis played a key role in the elucidation of the stereochemistry and verification of the constitution of the complex polymeric…”
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Total synthesis of conolidine and apparicine by Takanashi, Noriyuki, Suzuki, Kenta, Kitajima, Mariko, Takayama, Hiromitsu

“…[Display omitted] A total synthesis of indole alkaloids, (±)-conolidine and (±)-apparicine, was accomplished via a gold(I)-catalyzed 6-exo-dig cyclization to…”
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Asymmetric Total Synthesis of Pentacyclic Indole Alkaloid Andranginine and Absolute Configuration of Natural Product Isolated from Kopsia arborea by Tooriyama, Shino, Mimori, Yuji, Wu, Yuqiu, Kogure, Noriyuki, Kitajima, Mariko, Takayama, Hiromitsu

“…The first asymmetric total synthesis of andranginine (1) via an asymmetric Morita–Baylis–Hillman reaction and a diastereoselective intramolecular Diels–Alder…”
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Synthetic study of biphenylquinolizidine alkaloids I. Asymmetric total synthesis of lasubine I featuring organocatalyzed asymmetric intramolecular aza-Michael addition by Hirama, Taku, Umemura, Takayuki, Kogure, Noriyuki, Kitajima, Mariko, Takayama, Hiromitsu

“…[Display omitted] •An organocatalyzed asymmetric intramolecular aza-Michael addition of linear dienone was developed.•A new synthetic method of chiral…”
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Asymmetric Total Synthesis of Biphenylquinolizidine Alkaloids 4″‑O‑Demethyllythridine and 14-epi-4″‑O‑Demethyllythridine by Kawabata, Haruka, Hirama, Taku, Yanagisawa, Tomomi, Sato, Keigo, Kogure, Noriyuki, Kitajima, Mariko, Takayama, Hiromitsu

“…The first asymmetric total synthesis of new biphenylquinolizidine alkaloids 4″-O-demethyllythridine and 14-epi-4″-O-demethyllythridine isolated from Heimia…”
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New Lycopodine-Type Alkaloids from Lycopodium carinatum by Kogure, Noriyuki, Maruyama, Moe, Wongseripipatana, Sumphan, Kitajima, Mariko, Takayama, Hiromitsu

“…The structures of new lycopodine-type alkaloids, lycopocarinamines A–F, which were isolated from Lycopodium carinatum, were elucidated by spectroscopic…”
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Total synthesis of (±)-lycoposerramine-R, a novel skeletal type of Lycopodium alkaloid by Ishida, Hiroaki, Kimura, Shinya, Kogure, Noriyuki, Kitajima, Mariko, Takayama, Hiromitsu

“…The total synthesis of (±)-lycoposerramine-R, a novel skeletal type of Lycopodium alkaloid, was accomplished via the Diels–Alder reaction, the stereoselective…”
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First Total Synthesis of Trimeric Indole Alkaloid, Psychotrimine by Matsuda, Yohei, Kitajima, Mariko, Takayama, Hiromitsu

“…The first total synthesis of (±)-psychotrimine, a novel trimeric indole alkaloid isolated from Psychotria rostrata, was achieved. In the total synthesis, the…”
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