Search Results - "Takashi Kitahara"

A Soluble Fiber Diet Increases Bacteroides fragilis Group Abundance and Immunoglobulin A Production in the Gut by Nakajima, Akihito, Sasaki, Takashi, Itoh, Kikuji, Kitahara, Takashi, Takema, Yoshinori, Hiramatsu, Keiichi, Ishikawa, Dai, Shibuya, Tomoyoshi, Kobayashi, Osamu, Osada, Taro, Watanabe, Sumio, Nagahara, Akihito

“…Immunoglobulin A (IgA) is essential for defense of the intestinal mucosa against harmful pathogens. Previous studies have shown that , the major phylum of gut…”
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Evaluation of the Antiemetic Effect of Premedication Optimized by Pharmaceutical Support in Cisplatin Regimens by Ozaki, Masakazu, Kouda, Kyoji, Kitahara, Takashi

“…Cisplatin is classified as a drug with high emetic risk; thus, the use of aprepitant or fosaprepitant in addition to a 5-hydroxytryptamine-3 (5-HT3) receptor…”
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Autophagy Has a Significant Role in Determining Skin Color by Regulating Melanosome Degradation in Keratinocytes by Murase, Daiki, Hachiya, Akira, Takano, Kei, Hicks, Rachel, Visscher, Marty O., Kitahara, Takashi, Hase, Tadashi, Takema, Yoshinori, Yoshimori, Tamotsu

“…Melanin in the epidermis determines the wide variation in skin color associated with ethnic skin diversity. Ethnic differences exist regarding melanosome loss…”
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Changes in the Ceramide Profile of Atopic Dermatitis Patients by Ishikawa, Junko, Narita, Hirofumi, Kondo, Naoki, Hotta, Mitsuyuki, Takagi, Yutaka, Masukawa, Yoshinori, Kitahara, Takashi, Takema, Yoshinori, Koyano, Satomi, Yamazaki, Soji, Hatamochi, Atsushi

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Methotrexate-Coated Complexes of Plasmid DNA and Polyethylenimine for Gene Delivery by Kodama, Yukinobu, Noda, Ryo, Sato, Kayoko, Harasawa, Hitomi, Kurosaki, Tomoaki, Nakagawa, Hiroo, Nakamura, Tadahiro, Kitahara, Takashi, Muro, Takahiro, Sasaki, Hitoshi

“…Folate receptors are overexpressed on the surface cancer cells. We successfully constructed a new gene delivery vector of methotrexate (MTX)-coated plasmid…”
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Characterization of overall ceramide species in human stratum corneum by Masukawa, Yoshinori, Narita, Hirofumi, Shimizu, Eri, Kondo, Naoki, Sugai, Yoshiya, Oba, Tsuyoshi, Homma, Rika, Ishikawa, Junko, Takagi, Yutaka, Kitahara, Takashi, Takema, Yoshinori, Kita, Katsumi

“…Ceramides (CERs) in human stratum corneum (SC) play physicochemical roles in determining barrier and water-holding functions of the skin, and specific species…”
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Treatment of Inflammatory Bowel Disease with Biologics in Japan: A Single-Center, Retrospective Pharmacoeconomic Study by Saisyo, Atsuyuki, Hashimoto, Shinichi, Ishida, Haku, Kashibe, Koichi, Oka, Tomoyuki, Hirano, Yasushi, Takasago, Miwako, Uchida, Yutaka, Okada, Naoto, Takami, Taro, Kitahara, Takashi

“…Biologics are essential for treating inflammatory bowel disease (IBD); however, only a few studies have validated cost-effective treatment options and patient…”
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Comprehensive quantification of ceramide species in human stratum corneum[S] by Masukawa, Yoshinori, Narita, Hirofumi, Sato, Hirayuki, Naoe, Ayano, Kondo, Naoki, Sugai, Yoshiya, Oba, Tsuyoshi, Homma, Rika, Ishikawa, Junko, Takagi, Yutaka, Kitahara, Takashi

“…One of the key challenges in lipidomics is to quantify lipidomes of interest, as it is practically impossible to collect all authentic materials covering the…”
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Splenic Delivery System of pDNA through Complexes Electrostatically Constructed with Protamine and Chondroitin Sulfate by Kodama, Yukinobu, Nishigaki, Waka, Nakamura, Tadahiro, Fumoto, Shintaro, Nishida, Koyo, Kurosaki, Tomoaki, Nakagawa, Hiroo, Kitahara, Takashi, Muro, Takahiro, Sasaki, Hitoshi

“…We developed and optimized a novel gene delivery vector constructed electrostatically with an anionic biological component and a cationic biological component…”
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Variations in the ceramide profile in different seasons and regions of the body contribute to stratum corneum functions by Ishikawa, Junko, Shimotoyodome, Yoshie, Ito, Shotaro, Miyauchi, Yuki, Fujimura, Tsutomu, Kitahara, Takashi, Hase, Tadashi

“…The objective of this study was to clarify variations of the ceramide (CER) profile in human stratum corneum (SC) in different seasons and in different regions…”
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Positioning of Bristol Stool Form Scale type 3 in constipation treatment satisfaction: A multicenter study in Japan by Yamada, Eiji, Tsunoda, Seishi, Mimura, Masumi, Akizuki, Masashi, Miyazawa, Yoichiro, Yamazaki, Toshihiro, Nagano, Yasuhiko, Murakami, Reiko, Kitahara, Takashi, Wakasugi, Junichi, Ozawa, Yukihiro, Komatsu, Tatsuji, Inamori, Masahiko, Nagai, Kazuki, Nakajima, Atsushi

“…Background and Aim Many patients are not satisfied with chronic constipation (CC) treatments. The aim of this study was to identify factors linked to CC…”
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Clinical Impact of Antipolyethylene Glycol (PEG) Antibody in Hematological Patients Administered PEGylated‐Granulocyte Colony‐Stimulating Factor by Okada, Naoto, Taro, Shimizu, Ando, Hidenori, Nakamura, Shingen, Goda, Mitsuhiro, Abe, Masahiro, Kitahara, Takashi, Ishida, Tatsuhiro, Ishizawa, Keisuke

“…Polyethylene glycol (PEG) is a polymer covalently attached to proteins to improve their half‐life and efficacy. We previously reported that the PEGylated…”
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The Essential Role of p53 in Hyperpigmentation of the Skin via Regulation of Paracrine Melanogenic Cytokine Receptor Signaling by Murase, Daiki, Hachiya, Akira, Amano, Yasuko, Ohuchi, Atsushi, Kitahara, Takashi, Takema, Yoshinori

“…Hyperpigmentation of the skin is characterized by increases in melanin synthesis and deposition. Although considered a significant psychosocial distress,…”
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Positional differences and aging changes in Japanese woman epidermal thickness and corneous thickness determined by OCT (optical coherence tomography) by Tsugita, Tetsuya, Nishijima, Takafumi, Kitahara, Takashi, Takema, Yoshinori

“…A number of studies of the internal structure of Japanese woman's skin are now performed by means of optical coherence tomography (OCT) as a technique capable…”
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Analysis of vaporized caffeine in smoke from e-cigarettes using liquid chromatography–tandem mass spectrometry and clarification of minor components by Takada, Makoto, Saruwatari, Suzuna, Yanagita, Yutaro, Mutoh, Junpei, Harada, Hajime, Kishikawa, Naoya, Kitahara, Takashi, Kuroda, Naotaka, Wada, Mitsuhiro

“…Purpose Electronic cigarettes (e-cigarettes) are used widely, and e-cigarettes containing caffeine (Caf) have recently become commercially available. However,…”
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Pharmacoeconomic study of biologics for psoriasis treatment based on real‐world drug survival by Saisyo, Atsuyuki, Yamaguchi, Michiya, Kashibe, Koichi, Ishida, Haku, Hirano, Yasushi, Oka, Tomoyuki, Tamura, Miho, Takasago, Miwako, Uchida, Yutaka, Kouda, Kyoji, Kitahara, Takashi

“…The efficacy of biologics in psoriasis treatment is clinically proven; however, biologics are expensive. In this study, we assessed the real‐world…”
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Bibliometric analysis of pharmacist’s research on antimicrobial stewardship in Japan: an interrupted time series analysis on the implementation of the certification system for infection control pharmacists by Maeda, Masayuki, Miyake, Takefumi, Inose, Ryo, Ueda, Satoru, Matsugi, Ken-ichi, Muraki, Yuichi, Kitahara, Takashi

“…Background Pharmacist plays an integral role in promoting antimicrobial stewardship (AS) strategies by committing to the evidence-based activities in this…”
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Loss of skin elasticity precedes to rapid increase of wrinkle levels by Fujimura, Tsutomu, Haketa, Keiichi, Hotta, Mitsuyuki, Kitahara, Takashi

“…Summary Background Decreased skin elasticity is considered as a factor that promotes wrinkle formation. However, the relationship between decreased skin…”
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Secure Splenic Delivery of Plasmid DNA and Its Application to DNA Vaccine by Kurosaki, Tomoaki, Kodama, Yukinobu, Muro, Takahiro, Higuchi, Norihide, Nakamura, Tadahiro, Kitahara, Takashi, Miyakoda, Mana, Yui, Katsuyuki, Sasaki, Hitoshi

“…In this experiment, we developed a novel safe and effective gene delivery vector coated with γ-polyglutamic acid (γ-PGA-coated complexes). The γ-PGA-coated…”
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Expression of steroidogenic enzymes in human sebaceous glands by Inoue, Takayoshi, Miki, Yasuhiro, Kakuo, Shingo, Hachiya, Akira, Kitahara, Takashi, Aiba, Setsuya, Zouboulis, Christos C, Sasano, Hironobu

“…Androgens are well known to influence sebum synthesis and secretion. Various factors related to androgen biosynthesis are expressed in human sebaceous glands…”
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