Search Results - "Takao, Yukari"

Antitumor effects of systemic and local immunization with a CTL-directed peptide in combination with a local injection of OK-432 by ONO, Takeharu, HARADA, Mamoru, YAMADA, Akira, TANAKA, Masahiro, TAKAO, Yukari, TANAKA, Yasuaki, MINE, Takashi, SAKAMOTO, Kikuo, NAKASHIMA, Tadashi, ITOH, Kyogo

“…PURPOSE: The accumulation of T cells into the tumor site is crucial for the elicitation of in vivo antitumor effects after cancer vaccination. In this study,…”
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A new epitope peptide derived from hepatitis C virus 1b possessing the capacity to induce cytotoxic T-lymphocytes in HCV1b-infected patients with HLA-A11, -A31, and -A33 by Matsueda, Satoko, Yamada, Akira, Takao, Yukari, Tamura, Mayumi, Komatsu, Nobukazu, Yutani, Shigeru, Ide, Tatsuya, Sata, Michio, Itoh, Kyogo

“…Hepatitis C virus (HCV) frequently causes chronic hepatitis, cirrhosis, and hepatocellular carcinoma after long-term persistent infection. Among various…”
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Nonmutated Self-Antigen-Derived Cancer Vaccine Peptides Elicit an IgE-Independent but Mast Cell-Dependent Immediate-Type Skin Reaction without Systemic Anaphylaxis by Yamada, Akira, Yano, Hirohisa, Takao, Yukari, Ono, Takeharu, Matsumoto, Tomoko, Itoh, Kyogo

“…We previously reported an unexpected phenomenon, i.e., several cancer vaccine peptides, including a cyclophilin B-derived peptide (CypB-84), elicited an…”
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Identification of new immunogenic peptides in conserved regions of hepatitis C virus (HCV) 1b with the potentiality to generate cytotoxic T lymphocytes in HCV1b+ HLA-A24+ patients by Takao, Yukari, Yamada, Akira, Yutani, Shigeru, Takedatsu, Hiroko, Ono, Takeharu, Etoh, Kojyu, Wang, Yi, Suzuki, Susumu, Ide, Tatsuya, Shimotohno, Kunitada, Sata, Michio, Itoh, Kyogo

“…Aim:  Hepatitis C virus (HCV) 1b is resistant to standard interferon therapy and has a high risk of developing into hepatocellular carcinoma at the late stage…”
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New Epitope Peptides Derived from Hepatitis C Virus (HCV) 2a Which Have the Capacity to Induce Cytotoxic T Lymphocytes in HLA-A2+ HCV-Infected Patients by Wang, Yi, Takao, Yukari, Harada, Mamoru, Yutani, Shigeru, Ide, Tatsuya, Sata, Michio, Itoh, Kyogo, Yamada, Akira

“…Because cytotoxic T lymphocytes (CTLs) play an important role in the specific immunotherapy of hepatitis C virus (HCV) infection, a series of CTL epitopes has…”
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Antibody Reactive to a Hepatitis C Virus (HCV)-Derived Peptide Capable of Inducing HLA-A2 Restricted Cytotoxic T Lymphocytes Is Detectable in a Majority of HCV-Infected Individuals without HLA-A2 Restriction by Takao, Yukari, Yamada, Akira, Yutani, Shigeru, Sata, Michio, Itoh, Kyogo

“…Hepatitis C virus (HCV) is a single‐strand RNA virus. Approximately 170 million people around the world are persistently infected and are at risk of liver…”
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Phase I clinical study of a personalized peptide vaccination for patients infected with hepatitis C virus (HCV) 1b who failed to respond to interferon-based therapy by Yutani, Shigeru, Yamada, Akira, Yoshida, Kazumi, Takao, Yukari, Tamura, Mayumi, Komatsu, Nobukazu, Ide, Tatsuya, Tanaka, Masatoshi, Sata, Michio, Itoh, Kyogo

“…Abstract To assess the safety and immune responses to a personalized peptide vaccination of hepatitis C virus (HCV) 1b-derived peptides, 12 HCV1b-positive…”
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Predictive Factors Associated with the Progression to Hepatic Failure Caused by Lamivudine-Resistant HBV by Kuwahara, Reiichiro, Kumashiro, Ryukichi, Ide, Tatsuya, Koga, Yuriko, Hino, Teruko, Hisamochi, Akiko, Tanaka, Kazuo, Ogata, Kei, Koga, Hiroyuki, Takao, Yukari, Sata, Michio

“…The aims of this study were to select the patients with a potential for progression to hepatic failure due to lamivudine-resistant HBV and to standardize the…”
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Identification of hepatitis C virus (HCV) 2a-derived epitope peptides having the capacity to induce cytotoxic T lymphocytes in human leukocyte antigen-A24 + and HCV2a-infected patients by Wang, Yi, Takao, Yukari, Harada, Mamoru, Komatsu, Nobukazu, Ono, Takeharu, Sata, Michio, Itoh, Kyogo, Yamada, Akira

“…Since virus-specific cytotoxic T lymphocytes (CTLs) play a critical role in preventing the spread of hepatitis C virus (HCV), vaccine-based HCV-specific CTL…”
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Serum levels of IgG to the peptide of HCV1b core at positions 35-44 correlated with persistent infection, while levels of IgG to the peptide of NS5A at positions 2132-2140 correlated with better prognosis in HCV-infected patients by TAKAO, Yukari, YAMADA, Akira, YUTANI, Shigeru, ONO, Takeharu, NAGAO, Yumiko, ANDO, Eiji, IDE, Tatsuya, ITOH, Kyogo, SATA, Michio

“…We previously reported that two IgG Abs to the hepatitis C virus (HCV), anti-core 35-44 (C35) and anti-NS5A 2132-2140 (NS5A2132), existed in the sera of the…”
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New Epitope Peptides Derived from Hepatitis C Virus (HCV) 2a Which Have the Capacity to Induce Cytotoxic T Lymphocytes in HLA-A2 super(+) HCV-Infected Patients by Wang, Yi, Takao, Yukari, Harada, Mamoru, Yutani, Shigeru, Ide, Tatsuya, Sata, Michio, Itoh, Kyogo, Yamada, Akira

“…Because cytotoxic T lymphocytes (CTLs) play an important role in the specific immunotherapy of hepatitis C virus (HCV) infection, a series of CTL epitopes has…”
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New epitope peptides derived from parathyroid hormone-related protein which have the capacity to induce prostate cancer-reactive cytotoxicT lymphocytes in HLA-A2+ prostate cancer patients by YAO, Akihisa, HARADA, Mamoru, ITOH, Kyogo, MATSUEDA, Satoko, ISHIHARA, Yuki, SHOMURA, Hiroki, TAKAO, Yukari, NOGUCHI, Masanori, MATSUOKA, Kei, HARA, Isao, KAMIDONO, Sadao

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New epitope peptides derived from parathyroid hormone-related protein which have the capacity to induce prostate cancer-reactive cytotoxic T lymphocytes in HLA-A2+ prostate cancer patients by Yao, Akihisa, Harada, Mamoru, Matsueda, Satoko, Ishihara, Yuki, Shomura, Hiroki, Takao, Yukari, Noguchi, Masanori, Matsuoka, Kei, Hara, Isao, Kamidono, Sadao, Itoh, Kyogo

“…BACKGROUND Parathyroid hormone‐related protein (PTHrP) is produced by cancer cells and has been suggested to be responsible for malignancy‐associated…”
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New type of natural antibodies reactive to cytotoxic T lymphocyte-directed cancer vaccine peptides by Fukuda, Kunie, Takao, Yukari, Miyazaki, Yuki, Itoh, Kyogo, Yamada, Akira

“…We recently reported the existence of antibodies (Abs) reactive to cytotoxic T lymphocyte-directed cancer vaccine peptides derived from non-mutated and…”
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