Search Results - "Takano, Kei"

Autophagy Has a Significant Role in Determining Skin Color by Regulating Melanosome Degradation in Keratinocytes by Murase, Daiki, Hachiya, Akira, Takano, Kei, Hicks, Rachel, Visscher, Marty O., Kitahara, Takashi, Hase, Tadashi, Takema, Yoshinori, Yoshimori, Tamotsu

“…Melanin in the epidermis determines the wide variation in skin color associated with ethnic skin diversity. Ethnic differences exist regarding melanosome loss…”
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Depigmentation caused by application of the active brightening material, rhododendrol, is related to tyrosinase activity at a certain threshold by Kasamatsu, Shinya, Hachiya, Akira, Nakamura, Shun, Yasuda, Yuka, Fujimori, Taketoshi, Takano, Kei, Moriwaki, Shigeru, Hase, Tadashi, Suzuki, Tamio, Matsunaga, Kayoko

“…Highlights • We investigate the causes of unexpected depigmentation induced by rhododendrol. • Melanocyte damage is related to tyrosinase activity at a certain…”
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Quantitative changes in the secretion of exosomes from keratinocytes homeostatically regulate skin pigmentation in a paracrine manner by Takano, Kei, Hachiya, Akira, Murase, Daiki, Tanabe, Hiroki, Kasamatsu, Shinya, Takahashi, Yoshito, Moriwaki, Shigeru, Hase, Tadashi

“…The content and distribution of melanin in the epidermis determines the wide variety of skin colors associated with ethnic/racial diversity. Although it was…”
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5‐Lipoxygenase and cysteinyl leukotriene receptor 1 regulate epidermal growth factor‐induced cell migration through Tiam1 upregulation and Rac1 activation by Magi, Shigeyuki, Takemoto, Yasushi, Kobayashi, Hiroki, Kasamatsu, Masato, Akita, Takahiro, Tanaka, Ayako, Takano, Kei, Tashiro, Etsu, Igarashi, Yasuhiro, Imoto, Masaya

“…Cell migration is an essential step for tumor metastasis. The small GTPase Rac1 plays an important role in cell migration. Previously, we reported that…”
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The Surprising Effect of Phenformin on Cutaneous Darkening and Characterization of Its Underlying Mechanism by a Forward Chemical Genetics Approach by Takano, Kei, Hachiya, Akira, Murase, Daiki, Kawasaki, Akiko, Uda, Hirokazu, Kasamatsu, Shinya, Sugai, Yoshiya, Takahashi, Yoshito, Hase, Tadashi, Ohuchi, Atsushi, Suzuki, Tamio

“…Melanin in the epidermis is known to ultimately regulate human skin pigmentation. Recently, we exploited a phenotypic-based screening system composed of ex…”
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Involvement of 14-3-3 Proteins in the Second Epidermal Growth Factor-induced Wave of Rac1 Activation in the Process of Cell Migration by Kobayashi, Hiroki, Ogura, Yusuke, Sawada, Masato, Nakayama, Ryoji, Takano, Kei, Minato, Yusuke, Takemoto, Yasushi, Tashiro, Etsu, Watanabe, Hidenori, Imoto, Masaya

“…Immense previous efforts have elucidated the core machinery in cell migration, actin remodeling regulated by Rho family small GTPases including RhoA, Cdc42,…”
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Risk factors for discontinuation of exclusive breast feeding within 1month: a retrospective cohort study in Japan by Yasuda, Shun, Fukuda, Toma, Toba, Naoya, Kamo, Norihito, Imaizumi, Karin, Yokochi, Midori, Okawara, Tomoko, Takano, Seiko, Yoshida, Hideko, Kobayashi, Nobuko, Kudo, Shingo, Miyazaki, Kyohei, Hosoya, Mamiko, Sato, Kenichi, Takano, Kei, Kanno, Aya, Murata, Tsuyoshi, Kyozuka, Hyo, Yamaguchi, Akiko, Ito, Fumihiro, Oda, Shinichiro, Momoi, Nobuo, Hosoya, Mitsuaki, Fujimori, Keiya

“…While breastfeeding provides benefits for infants and the mother, many women either do not breastfeed or terminate breastfeeding earlier than recommended. The…”
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Incidence and index of severity of hemolytic uremic syndrome in a 26 year period in Fukushima Prefecture, Japan by Kawasaki, Yukihiko, Suyama, Kazuhide, Maeda, Ryo, Yugeta, Eichi, Takano, Kei, Suzuki, Shigeo, Sakuma, Hiroko, Nemoto, Kenji, Sato, Tomoko, Nagasawa, Katsutoshi, Hosoya, Mitsuaki

“…Background There have been a number of reports on large outbreaks of hemolytic uremic syndrome (HUS), but there have been no long‐term studies of sporadic HUS…”
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Transient Electric Field Analysis in Consideration of the Electric Field Dependence of Resistivity in the Converter Transformer by TERAKURA, TAKUMA, TAKANO, KEI, YASUOKA, TAKANORI, MORI, SHIGEKAZU, HOSOKAWA, OSAMU, IWABUCHI, TAKASHI, CHIGIRI, TAKASHI, YAMADA, SHIN

“…SUMMARY In this paper, values of the electric field in the pressboard and oil during the polarity reversal test of the converter transformer were calculated…”
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Two children with obesity‐related glomerulopathy identified in a school urinary screening program by Kawasaki, Yukihiko, Isome, Masato, Ono, Atsushi, Suzuki, Yuichi, Takano, Kei, Suyama, Kazuhide, Hosoya, Mitsuaki

“…The incidence of obesity‐related glomerulopathy (ORG) has increased over the last decade, but there have been few reports on ORG in Japanese children. Reported…”
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Efficacy of tonsillectomy pulse therapy versus multiple-drug therapy for IgA nephropathy by Kawasaki, Yukihiko, Takano, Kei, Suyama, Kazuhide, Isome, Masato, Suzuki, Hideki, Sakuma, Hiroko, Fujiki, Tomoo, Suzuki, Hitoshi, Hosoya, Mitsuaki

“…We evaluated the efficacy of tonsillectomy plus pulse prednisolone, warfarin, and dipyridamole including methylprednisolone pulse (tonsillectomy plus pulse…”
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Tonsillectomy with Methylprednisolone Pulse Therapy as Rescue Treatment for Steroid-Resistant IgA Nephropathy in Children by Kawasaki, Yukihiko, Suyama, Kazuhide, Abe, Yusaku, Ushijima, Yumiko, Sakai, Nobuko, Takano, Kei, Ito, Masaki, Hashimoto, Koichi, Hosoya, Mitsuaki

“…Primary immunoglobulin A (IgA) nephropathy is characterized by microhematuria and proteinuria and by the deposition of IgA in the glomerular mesangium. Steroid…”
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Development of Glomerular Endothelial Cells, Podocytes and Mesangial Cells in the Human Fetus and Infant by Takano, Kei, Kawasaki, Yukihiko, Imaizumi, Tomoko, Matsuura, Hiromi, Nozawa, Ruriko, Tannji, Mieko, Suyama, Kazuhide, Isome, Masato, Suzuki, Hitoshi, Hosoya, Mitsuaki

“…The process of glomerular development consists of four developmental stages: vesicle (V) stage, S-shaped body (S) stage, capillary loop (C) stage and…”
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IgA Nephropathy in a Patient with Dominant Dystrophic Epidermolysis Bullosa by Kawasaki, Yukihiko, Isome, Masato, Takano, Kei, Suyama, Kazuhide, Imaizumi, Tomoko, Matsuura, Hiromi, Ichii, Kiyoko, Hashimoto, Koichi, Hosoya, Mitsuaki

“…Dystrophic epidermolysis bullosa (DEB) is a rare and severe hereditary dermatosis. On the other hand, IgA nephropathy is the most common form of…”
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Carbon dioxide-induced decrease in extracellular pH enhances the production of extracellular matrix components by upregulating TGF-β1 expression via CREB activation in human dermal fibroblasts by Takano, Kei, Kasamatsu, Shinya, Aoki, Mika, Takahashi, Yoshito

“…Mild acidification caused by transcutaneous administration of carbon dioxide (CO ) has been reported to improve some epidermal skin impairments, such as…”
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Efficacy of Tonsillectomy Plus Methylprednisolone Pulse Therapy for a Child with Henoch-Schoenlein Purpura Nephritis by Kawasaki, Yukihiko, Suyama, Kazuhide, Matsumoto, Ayumi, Takano, Kei, Hashimoto, Koichi, Suzuki, Sigeo, Suzuki, Junzo, Suzuki, Hitoshi, Hosoya, Mitsuaki

“…Henoch-Schoenlein purpura (HSP) is a systemic disorder characterized by a leukocytoplastic vasculitis involving small vessels with the deposition of…”
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Featured Cover by Takano, Kei, Kasamatsu, Shinya, Aoki, Mika, Takahashi, Yoshito

“…The cover image is based on the ResearchArticle Carbon dioxide‐induced decrease in extracellular pH enhances theproduction of extracellular matrix components…”
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The leukotriene B4 receptor antagonist ONO-4057 inhibits mesangioproliferative changes in anti-Thy-1 nephritis by Kawasaki, Yukihiko, Tanji, Mieko, Takano, Kei, Fukuda, Yutaka, Isome, Masato, Nozawa, Ruriko, Suzuki, Hitoshi, Hosoya, Mitsuaki

“…Objective. ONO-4057 is a specific leukotriene B4 (LTB4) receptor antagonist which inhibits human neutrophil aggregation, chemotaxis and degranulation induced…”
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Efficacy of cyclosporine therapy for systemic lupus erythematosus in childhood by Kawasaki, Yukihiko, Hosoya, Mitsuaki, Takano, Kei, Suyama, Kazuhide, Nozawa, Ruriko, Isome, Masato, Suzuki, Junzo, Suzuki, Hitoshi

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Rosemary extract and rosmarinic acid accelerate elastic fiber formation by increasing the expression of elastic fiber components in dermal fibroblasts by Kasamatsu, Shinya, Takano, Kei, Aoki, Mika, Takahashi, Yoshito, Suzuki, Tamio

“…Ultraviolet (UV)‐induced skin photoaging is caused by qualitative and quantitative degradation of dermal extracellular matrix components such as collagen and…”
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