Search Results - "Takano, Ana Paula"
-
1
AT1 receptor blockage impairs NF-κB activation mediated by thyroid hormone in cardiomyocytes
Published in Pflügers Archiv (01-03-2018)“…We have previously demonstrated that calcium-binding protein S100A8 and myeloid differentiation factor-88 (MyD88) are important mediators of nuclear…”
Get full text
Journal Article -
2
Set7 deletion attenuates isoproterenol-induced cardiac fibrosis and delays cardiac dysfunction
Published in Clinical science (1979) (30-11-2022)“…Cardiovascular diseases are the main cause of death worldwide. Recent studies have revealed the influence of histone-modifying enzymes in cardiac remodeling…”
Get more information
Journal Article -
3
A comprehensive guide to western blotting for tendon research
Published in Analytical biochemistry (01-07-2024)“…Tendons are classified as dense fibrous connective tissue. This fibrous composition poses challenges in protein extraction, particularly hindering the…”
Get full text
Journal Article -
4
The endocrinological component and signaling pathways associated to cardiac hypertrophy
Published in Molecular and cellular endocrinology (01-12-2020)“…Although myocardial growth corresponds to an adaptive response to maintain cardiac contractile function, the cardiac hypertrophy is a condition that occurs in…”
Get full text
Journal Article -
5
Ablation of miRNA-22 protects against obesity-induced adipocyte senescence and ameliorates metabolic disorders in middle-aged mice
Published in Mechanisms of ageing and development (01-03-2023)“…High-fat diet (HFD) promotes obesity-related metabolic complications by activating cellular senescence in white adipose tissue (WAT). Growing evidence supports…”
Get full text
Journal Article -
6
S100A8/MYD88/NF-Ò>B: a novel pathway involved in cardiomyocyte hypertrophy driven by thyroid hormone
Published in Journal of molecular medicine (Berlin, Germany) (01-06-2017)“…Abstract Recent studies have evidenced the involvement of inflammation-related pathways to the development of cardiac hypertrophy and other consequences on the…”
Get full text
Journal Article -
7
Pleural anthracosis as an indicator of lifetime exposure to urban air pollution: An autopsy-based study in Sao Paulo
Published in Environmental research (01-06-2019)“…Many studies have been conducted to evaluate the association between air pollution and adverse health effects using a wide variety of methods to assess…”
Get full text
Journal Article -
8
Aerobic exercise training combined or not with okra consumption as a strategy to prevent kidney changes caused by metabolic syndrome in Zucker rats
Published in PloS one (03-06-2022)“…The complications of Metabolic Syndrome (MetS) include kidney disease, and most dialysis patients are diagnosed with MetS. The benefit of exercise training…”
Get full text
Journal Article -
9
AMPK signaling pathway is rapidly activated by T3 and regulates the cardiomyocyte growth
Published in Molecular and cellular endocrinology (25-08-2013)“…•T3 rapidly activated AMPK and proteins related to the AMPK signaling pathway.•The activation of AMPK blunted thyroid hormone induced cardiomyocyte…”
Get full text
Journal Article -
10
Deficiency of MicroRNA miR-1954 Promotes Cardiac Remodeling and Fibrosis
Published in Journal of the American Heart Association (05-11-2019)“…Background Cardiac fibrosis occurs because of disruption of the extracellular matrix network leading to myocardial dysfunction. Angiotensin II (AngII) has been…”
Get full text
Journal Article -
11
A New Method Proposed for the Estimation of Exposure to Atmospheric Pollution through the Analysis of Black Pigments on the Lung Surface
Published in Atmosphere (01-09-2024)“…Megacities can be considered excellent laboratories for studying the effects of the urban environment on human health. Typically, exposure to pollution is…”
Get full text
Journal Article -
12
M-Protein Is Down-Regulated in Cardiac Hypertrophy Driven by Thyroid Hormone in Rats
Published in Molecular endocrinology (Baltimore, Md.) (01-12-2013)“…Although it is well known that the thyroid hormone (T3) is an important positive regulator of cardiac function over a short term and that it also promotes…”
Get full text
Journal Article -
13
New insight into the mechanisms associated with the rapid effect of T3 on AT1R expression
Published in Journal of molecular endocrinology (01-08-2012)“…The angiotensin II type 1 receptor (AT1R) is involved in the development of cardiac hypertrophy promoted by thyroid hormone. Recently, we demonstrated that…”
Get full text
Journal Article -
14
Association of pulmonary black carbon accumulation with cardiac fibrosis in residents of Sao Paulo, Brazil
Published in Environmental research (01-05-2024)“…Evidence suggests that myocardial interstitial fibrosis, resulting from cardiac remodeling, may possibly be influenced by mechanisms activated through the…”
Get full text
Journal Article -
15
S100A8/MYD88/NF-қB: a novel pathway involved in cardiomyocyte hypertrophy driven by thyroid hormone
Published in Journal of molecular medicine (Berlin, Germany) (01-06-2017)“…Recent studies have evidenced the involvement of inflammation-related pathways to the development of cardiac hypertrophy and other consequences on the…”
Get full text
Journal Article -
16
Abstract P314: Loss Of Set7 Prevents Isoproterenol-induced Heart Dysfunction
Published in Hypertension (Dallas, Tex. 1979) (01-09-2022)“…Abstract only Recent studies have revealed the influence of histone-modifying enzymes in cardiac remodeling and dysfunction. The Set7 methyltransferase…”
Get full text
Journal Article -
17
NF‐қB Activation is Required for Thyroid Hormone Induced Cardiomyocyte Hypertrophy
Published in The FASEB journal (01-04-2015)“…Abstract only The nuclear factor NF‐қB promotes inflammatory response and mediates cardiac growth by different hypertrophic stimuli. We have previous results…”
Get full text
Journal Article -
18
miRNA-208a and miRNA-208b are triggered in thyroid hormone-induced cardiac hypertrophy – Role of type 1 Angiotensin II receptor (AT1R) on miRNA-208a/α-MHC modulation
Published in Molecular and cellular endocrinology (15-07-2013)“…•Like β-MHC, miR-208b is down-regulated in the hyperthyroid group.•Similarly to α-MHC, the miR-208a expression is increased in hyperthyroidism.•AT1R mediates…”
Get full text
Journal Article -
19
Microarray approach in experimental hyperthyroidism reveals two novel responsive genes in the rat heart (1148.8)
Published in The FASEB journal (01-04-2014)“…In order to get further insight upon the effects of Thyroid hormone (T3) in the heart, we have used a microarray approach to identify responsive genes in rats…”
Get full text
Journal Article -
20
LONG-TERM EXPOSURE TO AIR POLLUTION AND DEMENTIA: A LARGE CLINICOPATHOLOGICAL STUDY
Published in Alzheimer's & dementia (01-07-2019)Get full text
Journal Article