Search Results - "Takanami, Keiko"
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The gastrin-releasing peptide/bombesin system revisited by a reverse-evolutionary study considering Xenopus
Published in Scientific reports (25-06-2021)“…Bombesin is a putative antibacterial peptide isolated from the skin of the frog, Bombina bombina . Two related (bombesin-like) peptides, gastrin-releasing…”
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Estrogens influence female itch sensitivity via the spinal gastrin-releasing peptide receptor neurons
Published in Proceedings of the National Academy of Sciences - PNAS (03-08-2021)“…There are sex differences in somatosensory sensitivity. Circulating estrogens appear to have a pronociceptive effect that explains why females are reported to…”
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Activation of Supraoptic Oxytocin Neurons by Secretin Facilitates Social Recognition
Published in Biological psychiatry (1969) (01-02-2017)“…Abstract Background Social recognition underlies social behavior in animals, and patients with psychiatric disorders associated with social deficits show…”
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Testosterone has sublayer-specific effects on dendritic spine maturation mediated by BDNF and PSD-95 in pyramidal neurons in the hippocampus CA1 area
Published in Brain research (12-11-2012)“…Abstract Testosterone has a number of important physiological roles and acts on peripheral target tissues and the central nervous system. Testosterone exerts…”
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The Amphibious Mudskipper: A Unique Model Bridging the Gap of Central Actions of Osmoregulatory Hormones Between Terrestrial and Aquatic Vertebrates
Published in Frontiers in physiology (14-08-2018)“…Body fluid regulation, or osmoregulation, continues to be a major topic in comparative physiology, and teleost fishes have been the subject of intensive…”
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A spinal microglia population involved in remitting and relapsing neuropathic pain
Published in Science (American Association for the Advancement of Science) (01-04-2022)“…Neuropathic pain is often caused by injury and diseases that affect the somatosensory system. Although pain development has been well studied, pain recovery…”
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Function of gastrin-releasing peptide receptors in ocular itch transmission in the mouse trigeminal sensory system
Published in Frontiers in molecular neuroscience (30-11-2023)“…The prevalence of allergic conjunctivitis in itchy eyes has increased constantly worldwide owing to environmental pollution. Currently, anti-allergic and…”
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Inhibition of itch by neurokinin 1 receptor (Tacr1) -expressing ON cells in the rostral ventromedial medulla in mice
Published in eLife (16-08-2022)“…The rostral ventromedial medulla (RVM) is important in descending modulation of spinal nociceptive transmission, but it is unclear if the RVM also modulates…”
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The Gastrin-Releasing Peptide Receptor (GRPR) in the Spinal Cord as a Novel Pharmacological Target
Published in Current neuropharmacology (01-09-2014)“…Gastrin-releasing peptide (GRP) is a mammalian neuropeptide that acts through the G protein-coupled receptor, GRP receptor (GRPR). Increasing evidence…”
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Postnatal development of the gastrin-releasing peptide system in the lumbosacral spinal cord controlling male reproductive function in rats
Published in Proceedings of the Japan Academy, Series B (2016)“…A sexually dimorphic spinal gastrin-releasing peptide (GRP) system in the lumbosacral spinal cord, which projects to the lower spinal centers, controls…”
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Effects of sex steroids on the spinal gastrin-releasing peptide system controlling male sexual function in rats
Published in Endocrinology (Philadelphia) (01-04-2018)“…The gastrin-releasing peptide (GRP) system in the lumbosacral spinal cord controls male sexual function in rats. In contrast, in female rats, GRP neurons could…”
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Critical role of androgen receptor in the postnatal period in male sexual behavior in rats
Published in Neuroscience letters (16-11-2015)“…•The postnatal role of the androgen receptor (AR) in male sexual behavior was examined.•An AR antagonist given postnatally suppressed induction of intromission…”
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Effective synaptome analysis of itch-mediating neurons in the spinal cord: A novel immunohistochemical methodology using high-voltage electron microscopy
Published in Neuroscience letters (10-07-2015)“…•Here we report an effective synaptome using high-voltage electron microscopy (HVEM).•HVEM tomography is useful for studying three-dimensional (3-D) synaptic…”
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G protein-coupled receptor 30 contributes to improved remyelination after cuprizone-induced demyelination
Published in Glia (01-03-2013)“…Estrogen exerts neuroprotective and promyelinating actions. The therapeutic effect has been shown in animal models of multiple sclerosis, in which the myelin…”
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Nanobody-based RFP-dependent Cre recombinase for selective anterograde tracing in RFP-expressing transgenic animals
Published in Communications biology (16-09-2022)“…Transgenic animals expressing fluorescent proteins are widely used to label specific cells and proteins. By using a split Cre recombinase fused with…”
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Decrease in neuronal spine density in the postpartum period in the amygdala and bed nucleus of the stria terminalis in rat
Published in Neuroscience letters (22-02-2017)“…•Spine density in the (extended) amygdala was investigated in the peripartum period in rat.•The spine density was significantly decreased at 4days after…”
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Expression of G protein-coupled receptor 30 in the spinal somatosensory system
Published in Brain research (15-01-2010)“…Abstract Estrogens were originally identified as the primary sex steroid hormones in females and regulators of reproductive function and sexual behavior, but…”
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Comparative Anatomy of Gastrin-releasing Peptide Pathways in the Trigeminal Sensory System of Mouse and the Asian House Musk Shrew Suncus murinus
Published in ACTA HISTOCHEMICA ET CYTOCHEMICA (01-01-2016)“…Gastrin-releasing peptide (GRP) has recently been identified as an itch-signaling molecule in the primary afferents and spinal cord of rodents. However, little…”
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Expression of Sex Steroid Hormone Receptors in Vagal Motor Neurons Innervating the Trachea and Esophagus in Mouse
Published in ACTA HISTOCHEMICA ET CYTOCHEMICA (01-01-2016)“…The medullary vagal motor nuclei, the nucleus ambiguus (NA) and dorsal motor nucleus of the vagus (DMV), innervate the respiratory and gastrointestinal tracts…”
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Stress affects a gastrin-releasing peptide system in the spinal cord that mediates sexual function: implications for psychogenic erectile dysfunction
Published in PloS one (26-01-2009)“…Many men suffering from stress, including post-traumatic stress disorder (PTSD), report sexual dysfunction, which is traditionally treated via psychological…”
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