Search Results - "Takami, Yasunari"

Molecular mechanism of ER stress-induced pre-emptive quality control involving association of the translocon, Derlin-1, and HRD1 by Kadowaki, Hisae, Satrimafitrah, Pasjan, Takami, Yasunari, Nishitoh, Hideki

“…The maintenance of endoplasmic reticulum (ER) homeostasis is essential for cell function. ER stress-induced pre-emptive quality control (ERpQC) helps alleviate…”
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Acetylation of histone H4 lysine 5 and 12 is required for CENP-A deposition into centromeres by Shang, Wei-Hao, Hori, Tetsuya, Westhorpe, Frederick G., Godek, Kristina M., Toyoda, Atsushi, Misu, Sadahiko, Monma, Norikazu, Ikeo, Kazuho, Carroll, Christopher W., Takami, Yasunari, Fujiyama, Asao, Kimura, Hiroshi, Straight, Aaron F., Fukagawa, Tatsuo

“…Centromeres are specified epigenetically through the deposition of the centromere-specific histone H3 variant CENP-A. However, how additional epigenetic…”
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Pre-emptive Quality Control Protects the ER from Protein Overload via the Proximity of ERAD Components and SRP by Kadowaki, Hisae, Nagai, Atsushi, Maruyama, Takeshi, Takami, Yasunari, Satrimafitrah, Pasjan, Kato, Hironori, Honda, Arata, Hatta, Tomohisa, Natsume, Tohru, Sato, Takashi, Kai, Hirofumi, Ichijo, Hidenori, Nishitoh, Hideki

“…Cells possess ER quality control systems to adapt to ER stress and maintain their function. ER-stress-induced pre-emptive quality control (ER pQC) selectively…”
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Histone H1 quantity determines the efficiency of chromatin condensation in both apoptotic and live cells by Kijima, Marie, Yamagishi, Hiroyuki, Hara, Yasushi, Kasai, Mai, Takami, Yasunari, Takemura, Hiroshi, Miyanari, Yusuke, Shinkai, Yoichi, Mizuta, Ryushin

“…Although chromatin condensation is a well-known hallmark of apoptosis, the generation mechanism has not been clarified. Histone H1, a positively-charged…”
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Dicer is essential for formation of the heterochromatin structure in vertebrate cells by Fukagawa, Tatsuo, Nogami, Masahiro, Yoshikawa, Mitsuko, Ikeno, Masashi, Okazaki, Tuneko, Takami, Yasunari, Nakayama, Tatsuo, Oshimura, Mitsuo

“…RNA interference is an evolutionarily conserved gene-silencing pathway in which the nuclease Dicer cleaves double-stranded RNA into small interfering RNAs. The…”
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The Histone Chaperone Facilitates Chromatin Transcription (FACT) Protein Maintains Normal Replication Fork Rates by Abe, Takuya, Sugimura, Kazuto, Hosono, Yoshifumi, Takami, Yasunari, Akita, Motomu, Yoshimura, Akari, Tada, Shusuke, Nakayama, Tatsuo, Murofushi, Hiromu, Okumura, Katsuzumi, Takeda, Shunichi, Horikoshi, Masami, Seki, Masayuki, Enomoto, Takemi

“…Ordered nucleosome disassembly and reassembly are required for eukaryotic DNA replication. The facilitates chromatin transcription (FACT) complex, a histone…”
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GCN5 regulates the superoxide-generating system in leukocytes via controlling gp91-phox gene expression by Kikuchi, Hidehiko, Kuribayashi, Futoshi, Kiwaki, Naomi, Takami, Yasunari, Nakayama, Tatsuo

“…The superoxide anion (O(2)(-))-generating system is an important mechanism of innate immune response against microbial infection in phagocytes and is involved…”
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EBF1 acts as a powerful repressor of Blimp-1 gene expression in immature B cells by Kikuchi, Hidehiko, Nakayama, Masami, Takami, Yasunari, Kuribayashi, Futoshi, Nakayama, Tatsuo

“…► The transcription of the Blimp-1 was drastically up-regulated in EBF1-deficient DT40. ► The EBF1-deficiency also caused drastic increases in protein level of…”
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Lack of GCN5 remarkably enhances the resistance against prolonged endoplasmic reticulum stress-induced apoptosis through up-regulation of Bcl-2 gene expression by Kikuchi, Hidehiko, Kuribayashi, Futoshi, Mimuro, Hitomi, Imajoh-Ohmi, Shinobu, Nakayama, Masami, Takami, Yasunari, Nishitoh, Hideki, Nakayama, Tatsuo

“…The endoplasmic reticulum (ER), a complex membrane structure, has important roles in all eukaryotic cells. Catastrophe of its functions would lead to ER stress…”
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GCN5 regulates the activation of PI3K/Akt survival pathway in B cells exposed to oxidative stress via controlling gene expressions of Syk and Btk by Kikuchi, Hidehiko, Kuribayashi, Futoshi, Takami, Yasunari, Imajoh-Ohmi, Shinobu, Nakayama, Tatsuo

“…► The GCN5-deficiency remarkably causes apoptosis by H 2O 2 in chicken DT40 cells. ► Gene expressions of Syk and Btk are remarkably decreased in GCN5-deficient…”
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GCN5 is essential for IRF-4 gene expression followed by transcriptional activation of Blimp-1 in immature B cells by Kikuchi, Hidehiko, Nakayama, Masami, Kuribayashi, Futoshi, Imajoh‐Ohmi, Shinobu, Nishitoh, Hideki, Takami, Yasunari, Nakayama, Tatsuo

“…Histone acetyltransferase GCN5 plays key roles in cell differentiation via controlling IRF‐4 gene expression, followed by Blimp‐1 transcriptional activation in…”
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Essential role of chromatin assembly factor-1-mediated rapid nucleosome assembly for DNA replication and cell division in vertebrate cells by Takami, Yasunari, Ono, Tatsuya, Fukagawa, Tatsuo, Shibahara, Kei-ichi, Nakayama, Tatsuo

“…Chromatin assembly factor-1 (CAF-1), a complex consisting of p150, p60, and p48 subunits, is highly conserved from yeast to humans and facilitates nucleosome…”
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Histone H1 null vertebrate cells exhibit altered nucleosome architecture by Hashimoto, Hideharu, Takami, Yasunari, Sonoda, Eiichiro, Iwasaki, Tomohito, Iwano, Hidetomo, Tachibana, Makoto, Takeda, Shunichi, Nakayama, Tatsuo, Kimura, Hiroshi, Shinkai, Yoichi

“…In eukaryotic nuclei, DNA is wrapped around an octamer of core histones to form nucleosomes, and chromatin fibers are thought to be stabilized by linker…”
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GCN5 is involved in regulation of immunoglobulin heavy chain gene expression in immature B cells by Kikuchi, Hidehiko, Nakayama, Masami, Kuribayashi, Futoshi, Imajoh-Ohmi, Shinobu, Nishitoh, Hideki, Takami, Yasunari, Nakayama, Tatsuo

“…GCN5 is involved in the acetylation of core histones, which is an important epigenetic event for transcriptional regulation through alterations in the…”
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Paired box gene 5 isoforms A and B have different functions in transcriptional regulation of B cell development-related genes in immature B cells by Kikuchi, Hidehiko, Nakayama, Masami, Kuribayashi, Futoshi, Mimuro, Hitomi, Imajoh-Ohmi, Shinobu, Nishitoh, Hideki, Takami, Yasunari, Nakayama, Tatsuo

“…ABSTRACT The transcription factor paired box gene 5 (Pax5) is essential for B cell development. In this study, complementation analyses in Pax5‐deficient DT40…”
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Cleavage and Cytoplasmic Relocalization of Histone Deacetylase 3 Are Important for Apoptosis Progression by Escaffit, Fabrice, Vaute, Olivier, Chevillard-Briet, Martine, Segui, Bruno, Takami, Yasunari, Nakayama, Tatsuo, Trouche, Didier

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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GCN5: a supervisor in all-inclusive control of vertebrate cell cycle progression through transcription regulation of various cell cycle-related genes by Kikuchi, Hidehiko, Takami, Yasunari, Nakayama, Tatsuo

“…Histone acetyltransferases (HATs) are involved in the acetylation of core histones, which is an important event for transcription regulation through…”
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Asf1 Is Required for Viability and Chromatin Assembly during DNA Replication in Vertebrate Cells by Sanematsu, Fumiyuki, Takami, Yasunari, Barman, Hirak Kumar, Fukagawa, Tatsuo, Ono, Tatsuya, Shibahara, Kei-ichi, Nakayama, Tatsuo

“…Asf1 (anti-silencing function 1), a well conserved protein from yeast to humans, acts as a histone chaperone and is predicted to participate in a variety of…”
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Histone acetyltransferase p300/CBP-associated factor is an effective suppressor of secretory immunoglobulin synthesis in immature B cells by Kikuchi, Hidehiko, Nakayama, Masami, Kawai, Chikage, Kuribayashi, Futoshi, Mimuro, Hitomi, Imajoh-Ohmi, Shinobu, Nishitoh, Hideki, Takami, Yasunari, Nakayama, Tatsuo

“…ABSTRACT The histone acetyltransferase p300/CBP‐associated factor (PCAF) catalyzes acetylation of core histones and plays important roles in epigenetics by…”
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Histone acetyltransferase 1 is dispensable for replication-coupled chromatin assembly but contributes to recover DNA damages created following replication blockage in vertebrate cells by Barman, Hirak Kumar, Takami, Yasunari, Ono, Tatsuya, Nishijima, Hitoshi, Sanematsu, Fumiyuki, Shibahara, Kei-ichi, Nakayama, Tatsuo

“…Histone acetyltransferase 1 (HAT1) is implicated for diacetylation of Lys-5 and Lys-12 of newly synthesized histone H4, the biological significance of which…”
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