Search Results - "Takami, Masamichi"

Effects of Anti–Receptor Activator of Nuclear Factor Kappa B Ligand Antibody and Zoledronic Acid on Periapical Lesion Development in Mice by Ikeda, Megumi, Karakawa, Akiko, Takizawa, Hideomi, Azetsu, Yuki, Sakai, Nobuhiro, Chatani, Masahiro, Suzuki, Noriyuki, Takami, Masamichi

“…Antiresorptive drugs are widely used to treat osteoporosis and other systemic bone diseases, although their efficacy for local bone resorption after localized…”
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Pax5 Negatively Regulates Osteoclastogenesis through Downregulation of Blimp1 by Yu, Jiyeon, Kim, Sumi, Lee, Nari, Jeon, Hyoeun, Lee, Jun, Takami, Masamichi, Rho, Jaerang

“…Paired box protein 5 (Pax5) is a crucial transcription factor responsible for B-cell lineage specification and commitment. In this study, we identified a…”
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Bone loss caused by dopaminergic degeneration and levodopa treatment in Parkinson’s disease model mice by Handa, Kazuaki, Kiyohara, Shuichi, Yamakawa, Tomoyuki, Ishikawa, Koji, Hosonuma, Masahiro, Sakai, Nobuhiro, Karakawa, Akiko, Chatani, Masahiro, Tsuji, Mayumi, Inagaki, Katsunori, Kiuchi, Yuji, Takami, Masamichi, Negishi-Koga, Takako

“…Accumulating evidence have shown the association of Parkinson’s disease (PD) with osteoporosis. Bone loss in PD patients, considered to be multifactorial and a…”
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Cholesterol and fat in diet disrupt bone and tooth homeostasis in mice by Sato, Yurie, Hosonuma, Masahiro, Sugawara, Daiki, Azetsu, Yuki, Karakawa, Akiko, Chatani, Masahiro, Funatsu, Takahiro, Takami, Masamichi, Sakai, Nobuhiro

“…Dyslipidemia is a condition of high levels of triglycerides and cholesterol in the blood, and high levels of cholesterol is associated with a variety of…”
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Anti-mouse RANKL Antibodies Inhibit Alveolar Bone Destruction in Periodontitis Model Mice by Kuritani, Miku, Sakai, Nobuhiro, Karakawa, Akiko, Isawa, Motoki, Chatani, Masahiro, Negishi-Koga, Takako, Funatsu, Takahiro, Takami, Masamichi

“…Denosumab is an anti-bone resorptive drug consisting of complete human monoclonal antibodies that targets receptor activator of nuclear factor κB ligand…”
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Effects of lipid metabolism on mouse incisor dentinogenesis by Kurotaki, Yutaro, Sakai, Nobuhiro, Miyazaki, Takuro, Hosonuma, Masahiro, Sato, Yurie, Karakawa, Akiko, Chatani, Masahiro, Myers, Mie, Suzawa, Tetsuo, Negishi-Koga, Takako, Kamijo, Ryutaro, Miyazaki, Akira, Maruoka, Yasubumi, Takami, Masamichi

“…Tooth formation can be affected by various factors, such as oral disease, drug administration, and systemic illness, as well as internal conditions including…”
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Roles of monocarboxylate transporter subtypes in promotion and suppression of osteoclast differentiation and survival on bone by Imai, Hiroko, Yoshimura, Kentaro, Miyamoto, Yoichi, Sasa, Kiyohito, Sugano, Marika, Chatani, Masahiro, Takami, Masamichi, Yamamoto, Matsuo, Kamijo, Ryutaro

“…Monocarboxylate transporters (MCTs) provide transmembrane transport of monocarboxylates such as lactate and pyruvate. The present results showed that…”
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Treatment with synthetic glucocorticoid impairs bone metabolism, as revealed by in vivo imaging of osteoblasts and osteoclasts in medaka fish by Azetsu, Yuki, Chatani, Masahiro, Dodo, Yusuke, Karakawa, Akiko, Sakai, Nobuhiro, Negishi-Koga, Takako, Takami, Masamichi

“…•Prednisolone treatment impaired the bone metabolism in the pharyngeal bone.•Glucocorticoids suppressed osteoclast and osteoblast dynamics on fracture…”
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Biological Effects of Anti-RANKL Antibody and Zoledronic Acid on Growth and Tooth Eruption in Growing Mice by Isawa, Motoki, Karakawa, Akiko, Sakai, Nobuhiro, Nishina, Saki, Kuritani, Miku, Chatani, Masahiro, Negishi-Koga, Takako, Sato, Masashi, Inoue, Mitsuko, Shimada, Yukie, Takami, Masamichi

“…The anti-bone resorptive drugs denosumab, an anti-human-RANKL antibody, and zoledronic acid (ZOL), a nitrogen-containing bisphosphonate, have recently been…”
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Induction of osteoblastic differentiation of neural crest-derived stem cells from hair follicles by Urano-Morisawa, Eri, Takami, Masamichi, Suzawa, Tetsuo, Matsumoto, Akifumi, Osumi, Noriko, Baba, Kazuyoshi, Kamijo, Ryutaro

“…The neural crest (NC) arises near the neural tube during embryo development. NC cells migrate throughout the embryo and have potential to differentiate into…”
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RANKL+ senescent cells under mechanical stress: a therapeutic target for orthodontic root resorption using senolytics by Zhou, Yue, Nishiura, Aki, Morikuni, Hidetoshi, Deng, Wenqi, Tsujibayashi, Toru, Momota, Yoshihiro, Azetsu, Yuki, Takami, Masamichi, Honda, Yoshitomo, Matsumoto, Naoyuki

“…In dentistry, orthodontic root resorption is a long-lasting issue with no effective treatment strategy, and its mechanisms, especially those related to…”
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Myelination during fracture healing in vivo in myelin protein zero (p0) transgenic medaka line by Dodo, Yusuke, Chatani, Masahiro, Azetsu, Yuki, Hosonuma, Masahiro, Karakawa, Akiko, Sakai, Nobuhiro, Negishi-Koga, Takako, Tsuji, Mayumi, Inagaki, Katsunori, Kiuchi, Yuji, Takami, Masamichi

“…During the fracture healing process, osteoblasts and osteoclasts, as well as the nervous system are known to play important roles for signaling in the body…”
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Neural crest-derived cells possess differentiation potential to keratinocytes in the process of wound healing by Takizawa, Hideomi, Karakawa, Akiko, Suzawa, Tetsuo, Chatani, Masahiro, Ikeda, Megumi, Sakai, Nobuhiro, Azetsu, Yuki, Takahashi, Masahiro, Urano, Eri, Kamijo, Ryutaro, Maki, Koutaro, Takami, Masamichi

“…Neural crest-derived cells (NCDCs), which exist as neural crest cells during the fetal stage and differentiate into palate cells, also exist in adult palate…”
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Effects of anti-RANKL antibodies administered to pregnant mice on bone and tooth development in neonates by Yamaguchi, Maho, Takami, Masamichi, Azetsu, Yuki, Karakawa, Akiko, Chatani, Masahiro, Funatsu, Takahiro, Sakai, Nobuhiro

“…This study examined how the anti-bone resorptive agent denosumab, which comprises anti-receptor activator of nuclear factor kappa B ligand (anti-RANKL)…”
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Shared and distinct functions of the transcription factors IRF4 and IRF8 in myeloid cell development by Yamamoto, Michio, Kato, Takayuki, Hotta, Chie, Nishiyama, Akira, Kurotaki, Daisuke, Yoshinari, Masahiro, Takami, Masamichi, Ichino, Motohide, Nakazawa, Masatoshi, Matsuyama, Toshifumi, Kamijo, Ryutaro, Kitagawa, Seiichi, Ozato, Keiko, Tamura, Tomohiko

“…Interferon regulatory factor (IRF) 8 and IRF4 are structurally-related, hematopoietic cell-specific transcription factors that cooperatively regulate the…”
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identification of an osteoclastogenesis inhibitor through the inhibition of glyoxalase I by Kawatani, Makoto, Okumura, Hideo, Honda, Kaori, Kanoh, Naoki, Muroi, Makoto, Dohmae, Naoshi, Takami, Masamichi, Kitagawa, Mitsuhiro, Futamura, Yushi, Imoto, Masaya, Osada, Hiroyuki

“…Osteoclasts, bone-resorptive multinucleated cells derived from hematopoietic stem cells, are associated with many bone-related diseases, such as osteoporosis…”
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Enhancement of bone morphogenetic protein-2-induced ectopic bone formation by transforming growth factor-β1 by Tachi, Keita, Takami, Masamichi, Sato, Hana, Mochizuki, Ayako, Zhao, Baohong, Miyamoto, Yoichi, Tsukasaki, Hiroaki, Inoue, Tomio, Shintani, Satoru, Koike, Tatsuya, Honda, Yoshitomo, Suzuki, Osamu, Baba, Kazuyoshi, Kamijo, Ryutaro

“…Bone morphogenetic proteins (BMPs) possess osteoinductive activities and are useful for clinical treatments, including bone regeneration. We found that…”
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Osteoclast differentiation independent of the TRANCE-RANK-TRAF6 axis by Kim, Nacksung, Kadono, Yuho, Takami, Masamichi, Lee, Junwon, Lee, Seoung-Hoon, Okada, Fumihiko, Kim, Jung Ha, Kobayashi, Takashi, Odgren, Paul R, Nakano, Hiroyasu, Yeh, Wen-Chen, Lee, Sun-Kyeong, Lorenzo, Joseph A, Choi, Yongwon

“…Osteoclasts are derived from myeloid lineage cells, and their differentiation is supported by various osteotropic factors, including the tumor necrosis factor…”
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Stimulation by Toll-Like Receptors Inhibits Osteoclast Differentiation by Takami, Masamichi, Kim, Nacksung, Rho, Jaerang, Choi, Yongwon

“…Osteoclasts, the cells capable of resorbing bone, are derived from hemopoietic precursor cells of monocyte-macrophage lineage. The same precursor cells can…”
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Heparin enhances osteoclastic bone resorption by inhibiting osteoprotegerin activity by Irie, Atsushi, Takami, Masamichi, Kubo, Hideo, Sekino-Suzuki, Naoko, Kasahara, Kohji, Sanai, Yutaka

“…Abstract Heparin is a highly sulfated glycosaminoglycan and has been shown to activate osteoclastic bone resorption though how is not yet clear. Here we…”
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