Search Results - "Takakura, Kazuki"

The Clinical Potential of Oligonucleotide Therapeutics against Pancreatic Cancer by Takakura, Kazuki, Kawamura, Atsushi, Torisu, Yuichi, Koido, Shigeo, Yahagi, Naohisa, Saruta, Masayuki

“…Although many diagnostic and therapeutic modalities for pancreatic cancer have been proposed, an urgent need for improved therapeutic strategies remains…”
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Comparative assessment of sarcopenia using the JSH, AWGS, and EWGSOP2 criteria and the relationship between sarcopenia, osteoporosis, and osteosarcopenia in patients with liver cirrhosis by Saeki, Chisato, Takano, Keiko, Oikawa, Tsunekazu, Aoki, Yuma, Kanai, Tomoya, Takakura, Kazuki, Nakano, Masanori, Torisu, Yuichi, Sasaki, Nobuyuki, Abo, Masahiro, Matsuura, Tomokazu, Tsubota, Akihito, Saruta, Masayuki

“…Sarcopenia and osteoporosis reduce life quality and worsen prognosis in patients with liver cirrhosis (LC). When these two complications coexist, a diagnosis…”
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Recent Insights Into the Multiple Pathways Driving Non-alcoholic Steatohepatitis-Derived Hepatocellular Carcinoma by Takakura, Kazuki, Oikawa, Tsunekazu, Nakano, Masanori, Saeki, Chisato, Torisu, Yuichi, Kajihara, Mikio, Saruta, Masayuki

“…The incidence of metabolic syndrome with fatty liver is spreading on a worldwide scale. Correspondingly, the number of patients with the hepatic phenotype of…”
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Incidence of pancreatic cancer is dramatically increased by a high fat, high calorie diet in KrasG12D mice by Chang, Hui-Hua, Moro, Aune, Takakura, Kazuki, Su, Hsin-Yuan, Mo, Allen, Nakanishi, Masako, Waldron, Richard T, French, Samuel W, Dawson, David W, Hines, O Joe, Li, Gang, Go, Vay Liang W, Sinnett-Smith, James, Pandol, Stephen J, Lugea, Aurelia, Gukovskaya, Anna S, Duff, Michael O, Rosenberg, Daniel W, Rozengurt, Enrique, Eibl, Guido

“…Epidemiologic data has linked obesity to a higher risk of pancreatic cancer, but the underlying mechanisms are poorly understood. To allow for detailed…”
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Dendritic cell-based cancer immunotherapy for colorectal cancer by Kajihara, Mikio, Takakura, Kazuki, Kanai, Tomoya, Ito, Zensho, Saito, Keisuke, Takami, Shinichiro, Shimodaira, Shigetaka, Okamoto, Masato, Ohkusa, Toshifumi, Koido, Shigeo

“…Colorectal cancer(CRC) is one of the most common cancers and a leading cause of cancer-related mortality worldwide. Although systemic therapy is the standard…”
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Best period to replace or change plastic stents with self-expandable metallic stents using multivariate competing risk regression analysis by Chiba, Masafumi, Kato, Masayuki, Kinoshita, Yuji, Shimamoto, Nana, Tomita, Youichi, Abe, Takahiro, Kawahara, Yosuke, Koyama, Seita, Kanazawa, Keisuke, Takakura, Kazuki, Tsukinaga, Shintaro, Nakano, Masanori, Torisu, Yuichi, Toyoizumi, Hirobumi, Ikeda, Keiichi, Arakawa, Hiroshi, Sumiyama, Kazuki

“…In endoscopic biliary drainage (EBD) for various benign and malignant biliary disorders, the appropriate timing to replace or change a plastic stent (PS) with…”
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Roles of autophagy and metabolism in pancreatic cancer cell adaptation to environmental challenges by Maertin, Sandrina, Elperin, Jason M, Lotshaw, Ethan, Sendler, Matthias, Speakman, Steven D, Takakura, Kazuki, Reicher, Benjamin M, Mareninova, Olga A, Grippo, Paul J, Mayerle, Julia, Lerch, Markus M, Gukovskaya, Anna S

“…Pancreatic ductal adenocarcinoma (PDAC) displays extensive and poorly vascularized desmoplastic stromal reaction, and therefore, pancreatic cancer (PaCa) cells…”
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Inhibition of Cell Proliferation and Growth of Pancreatic Cancer by Silencing of Carbohydrate Sulfotransferase 15 In Vitro and in a Xenograft Model by Takakura, Kazuki, Shibazaki, Yuichiro, Yoneyama, Hiroyuki, Fujii, Masato, Hashiguchi, Taishi, Ito, Zensho, Kajihara, Mikio, Misawa, Takeyuki, Homma, Sadamu, Ohkusa, Toshifumi, Koido, Shigeo

“…Chondroitin sulfate E (CS-E), a highly sulfated glycosaminoglycan, is known to promote tumor invasion and metastasis. Because the presence of CS-E is detected…”
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Advances in inducing adaptive immunity using cell-based cancer vaccines: clinical applications in pancreatic cancer by Kajihara, Mikio, Takakura, Kazuki, Kanai, Tomoya, Ito, Zensho, Matsumoto, Yoshihiro, Shimodaira, Shigetaka, Okamoto, Masato, Ohkusa, Toshifumi, Koido, Shigeo

“…The incidence of pancreatic ductal adenocarcinoma(PDA) is on the rise, and the prognosis is extremely poor because PDA is highly aggressive and notoriously…”
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The impact of dendritic cell-tumor fusion cells on cancer vaccines - past progress and future strategies by Kajihara, Mikio, Takakura, Kazuki, Ohkusa, Toshifumi, Koido, Shigeo

“…Dendritic cells (DCs) are potent antigen-presenting cells that can be used in cancer vaccines. Thus, various strategies have been developed to deliver…”
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Gastric Tube Ulcer that Could Be Saved by Early Conservative Treatment by Koyama, Muneyuki, Shiba, Hiroaki, Takakura, Kazuki, Yamahata, Yuto, Otsuka, Sho, Odaka, Minako, Takagi, Keisuke, Takano, Yasuhiro, Eto, Ken

“…The patient was an 81-year-old man who had received subtotal esophagectomy for esophageal cancer reconstructed by a gastric tube via a posterior mediastinal…”
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Long-term alteration of intestinal microbiota in patients with ulcerative colitis by antibiotic combination therapy by Koido, Shigeo, Ohkusa, Toshifumi, Kajiura, Takayuki, Shinozaki, Junko, Suzuki, Manabu, Saito, Keisuke, Takakura, Kazuki, Tsukinaga, Shintaro, Odahara, Shunichi, Yukawa, Toyokazu, Mitobe, Jimi, Kajihara, Mikio, Uchiyama, Kan, Arakawa, Hiroshi, Tajiri, Hisao

“…Previous work has demonstrated that intestinal bacteria, such as Fusobacterium varium (F. varium), contribute to the clinical activity in ulcerative colitis…”
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Prognostic significance of plasma interleukin-6/-8 in pancreatic cancer patients receiving chemoimmunotherapy by Tsukinaga, Shintaro, Kajihara, Mikio, Takakura, Kazuki, Ito, Zensho, Kanai, Tomoya, Saito, Keisuke, Takami, Shinichiro, Kobayashi, Hiroko, Matsumoto, Yoshihiro, Odahara, Shunichi, Uchiyama, Kan, Arakawa, Hiroshi, Okamoto, Masato, Sugiyama, Haruo, Sumiyama, Kazuki, Ohkusa, Toshifumi, Koido, Shigeo

“…AIM: To investigate the association of plasma levels of interleukin(IL)-6 and-8 with Wilms’ tumor 1(WT1)-specific immune responses and clinical outcomes in…”
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Production of corticotropin-releasing factor and urocortin from human monocyte-derived dendritic cells is stimulated by commensal bacteria in intestine by Koido, Shigeo, Ohkusa, Toshifumi, Kan, Shin, Takakura, Kazuki, Saito, Keisuke, Komita, Hideo, Ito, Zensho, Kobayashi, Hiroko, Takami, Shinichiro, Uchiyama, Kan, Arakawa, Hiroshi, Ito, Masaki, Okamoto, Masato, Kajihara, Mikio, Homma, Sadamu, Tajiri, Hisao

“…AIM:To examine whether commensal bacteria are a contributing cause of stress-related mucosal inflammation.METHODS:Human peripheral blood…”
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Impact of qualitative endoscopic ultrasonography on fatty pancreas at a referral medical center by Kawamura, Atsushi, Takakura, Kazuki, Torisu, Yuichi, Kinoshita, Yuji, Tomita, Yoichi, Nakano, Masanori, Yamauchi, Takashi, Suka, Machi, Sumiyama, Kazuki, Koido, Shigeo, Saruta, Masayuki

“…Background Taking advantage of the current advances in diagnostic imaging modalities, including endoscopic ultrasonography (EUS), and due to the increased…”
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Endoscopic ultrasound‐guided fine‐needle biopsy histology with a 22‐gauge Franseen needle and fine‐needle aspiration liquid‐based cytology with a conventional 25‐gauge needle provide comparable diagnostic accuracy in solid pancreatic lesions by Tomita, Yoichi, Torisu, Yuichi, Chiba, Masafumi, Kinoshita, Yuji, Akasu, Takafumi, Shimamoto, Nana, Abe, Takahiro, Kanazawa, Keisuke, Takakura, Kazuki, Tsukinaga, Shintaro, Nakano, Masanori, Toyoizumi, Hirobumi, Kato, Masayuki, Saruta, Masayuki

“…Background and Aim Fine‐needle biopsy (FNB) needles obtain more core samples and support the shift from cytologic to histologic evaluation; however, recent…”
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Combined TLR2/4-activated dendritic/tumor cell fusions induce augmented cytotoxic T lymphocytes by Koido, Shigeo, Homma, Sadamu, Okamoto, Masato, Namiki, Yoshihisa, Takakura, Kazuki, Takahara, Akitaka, Odahara, Shunichi, Tsukinaga, Shintaro, Yukawa, Toyokazu, Mitobe, Jimi, Matsudaira, Hiroshi, Nagatsuma, Keisuke, Uchiyama, Kan, Kajihara, Mikio, Arihiro, Seiji, Imazu, Hiroo, Arakawa, Hiroshi, Kan, Shin, Komita, Hideo, Ito, Masaki, Ohkusa, Toshifumi, Gong, Jianlin, Tajiri, Hisao

“…Induction of antitumor immunity by dendritic cell (DC)-tumor fusion cells (DC/tumor) can be modulated by their activation status. In this study, to address…”
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Hemobilia Derived from Cystic Artery Pseudoaneurysm by Tanaka, Takayuki, Takakura, Kazuki, Maruyama, Yuki, Hidaka, Akihisa, Nakano, Masanori, Torisu, Yuichi, Saruta, Masayuki

“…Cystic artery pseudoaneurysm (CAP) is a rare disease, with small number of previous reports related to CAP. Besides, it is frequently prone to critical…”
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Augmentation of antitumor immunity by fusions of ethanol-treated tumor cells and dendritic cells stimulated via dual TLRs through TGF-β1 blockade and IL-12p70 production by Koido, Shigeo, Homma, Sadamu, Okamoto, Masato, Namiki, Yoshihisa, Takakura, Kazuki, Takahara, Akitaka, Odahara, Shunichi, Tsukinaga, Shintaro, Yukawa, Toyokazu, Mitobe, Jimi, Matsudaira, Hiroshi, Nagatsuma, Keisuke, Kajihara, Mikio, Uchiyama, Kan, Arihiro, Seiji, Imazu, Hiroo, Arakawa, Hiroshi, Kan, Shin, Hayashi, Kazumi, Komita, Hideo, Kamata, Yuko, Ito, Masaki, Hara, Eiichi, Ohkusa, Toshifumi, Gong, Jianlin, Tajiri, Hisao

“…The therapeutic efficacy of fusion cell (FC)-based cancer vaccine generated with whole tumor cells and dendritic cells (DCs) requires the improved…”
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Nested Culture Method Improves Detection of Fusobacterium from Stool in Patients with Ulcerative Colitis by Yukawa, Toyokazu, Ohkusa, Toshifumi, Shibuya, Tomoyoshi, Tsukinaga, Shintaro, Mitobe, Jimi, Takakura, Kazuki, Takahara, Akitaka, Odahara, Shunichi, Matsudaira, Hiroshi, Nagatsuma, Keisuke, Kitahara, Takuya, Kajihara, Mikio, Uchiyama, Kan, Arakawa, Hiroshi, Koido, Shigeo, Tajiri, Hisao

“…Fusobacterium varium is an elusive pathogenic factor in ulcerative colitis (UC); conventional methods of fecal culture rarely recover F. varium. We have…”
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