Search Results - "Takaku, F"

Bcl-2 down-regulation causes autophagy in a caspase-independent manner in human leukemic HL60 cells by Saeki, K, Yuo, A, Okuma, E, Yazaki, Y, Susin, S A, Kroemer, G, Takaku, F

“…To understand the roles of bcl-2 for the survival of leukemic cells, we constructed human leukemic HL60 transformant lines in which full length bcl-2 antisense…”
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Novel immunosuppressive agent, FK506. In vitro effects on the cloned T cell activation by Sawada, S, Suzuki, G, Kawase, Y, Takaku, F

“…The present study shows the in vitro effects of a novel immunosuppressive agent, FK506, in comparison with cyclosporin A (CsA). FK506 inhibited concanavalin A…”
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Effects of granulocyte colony‐stimulating factor and granulocyte‐macrophage colony‐stimulating factor on respiratory burst activity of neutrophiis in patients with myelodysplastic syndromes by OHSAKA, A., KITAGAWA, S., YUO, A., MOTOYOSHI, K., FURUSAWA, S., MIURA, Y., TAKAKU, F., SAITO, M.

“…SUMMARY The superoxide (O2‐releasing capacity in response lo N‐fomiyl‐methionyl‐leucyl‐phenylalanine (FMLP)and the priming effects ofrecombinant human…”
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Mechanical loading stimulates cell hypertrophy and specific gene expression in cultured rat cardiac myocytes. Possible role of protein kinase C activation by Komuro, I, Katoh, Y, Kaida, T, Shibazaki, Y, Kurabayashi, M, Hoh, E, Takaku, F, Yazaki, Y

“…To examine the molecular mechanisms by which mechanical stimuli induce cardiac hypertrophy and specific gene expression, we cultured rat neonatal cardiocytes…”
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Purification and properties of an endothelial cell growth factor from human platelets by Miyazono, K., Okabe, T., Urabe, A., Takaku, F., Heldin, C.H.

“…An endothelial cell growth factor has been purified about 1,000,000-fold to homogeneity from human platelets by a seven-step procedure. The purified product…”
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Stretching cardiac myocytes stimulates protooncogene expression by KOMURO, I, KAIDA, T, SHIBAZAKI, Y, KURABAYASHI, M, KATOH, Y, HOH, E, TAKAKU, F, YAZAKI, Y

“…Recently cellular protooncogenes have been found to be induced as an early response to pressure overload in cardiac hypertrophy. To examine whether mechanical…”
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Serum granulocyte colony-stimulating factor levels in healthy volunteers and patients with various disorders as estimated by enzyme immunoassay by Watari, K, Asano, S, Shirafuji, N, Kodo, H, Ozawa, K, Takaku, F, Kamachi, S

“…In order to better understand the patho-physiologic role of granulocyte colony-stimulating factor (G-CSF), we estimated its serum levels in healthy persons and…”
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Expression of Cellular Oncogenes in the Myocardium During the Developmental Stage and Pressure-Overloaded Hypertrophy of the Rat Heart by Komuro, Issei, Kurabayashi, Masahiko, Takaku, Fumimaro, Yazaki, Yoshio

“…Proto-oncogenes have been revealed to participate in normal cell proliferation as well as in cell transformation. Since cardiac myocytes are terminally…”
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Human Macrophage Scavenger Receptors: Primary Structure, Expression, and Localization in Atherosclerotic Lesions by Matsumoto, Akiyo, Naito, Markoto, Itakura, Hiroshige, Ikemoto, Shinji, Asaoka, Hitoshi, Hayakawa, Ikuho, Kanamori, Hiroshi, Aburtani, Hiroyuki, Takaku, Fumimaro, Suzuki, Hiroshi, Kobari, Yukage, Miyai, Tatsuya, Takahashi, Kiyoshi, Cohen, Edward H., Wydro, Robert, Housman, David E., Kodama, Tatsuhiko

“…Two types of cDNAs for human macrophage scavenger receptors were cloned from a cDNA library derived from the phorbol ester-treated human monocytic cell line…”
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Developmentally regulated expression of vascular smooth muscle myosin heavy chain isoforms by Kuro-o, M, Nagai, R, Tsuchimochi, H, Katoh, H, Yazaki, Y, Ohkubo, A, Takaku, F

“…Two types of smooth muscle myosin heavy chain (MHC) isoforms, SM1 and SM2, were recently identified to have different carboxyl termini (Nagai, R., Kuro-o, M.,…”
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Monocyte colony-stimulating factor enhances uptake and degradation of acetylated low density lipoproteins and cholesterol esterification in human monocyte-derived macrophages by ISHIBASHI, S, INABA, T, SHIMANO, H, HARADA, K, INOUE, I, MOKUNO, H, MORI, N, GOTODA, T, TAKAKU, F, YAMADA, N

“…We have investigated effects of monocyte colony-stimulating factor (M-CSF) on the uptake of acetylated low density lipoproteins (acetyl-LDL) and the activity…”
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Analysis of 500 bone marrow transplants from unrelated donors (UR-BMT) facilitated by the Japan Marrow Donor program : Confirmation of UR-BMT as a standard therapy for patients with leukemia and aplastic anemia by KODERA, Y, MORISHIMA, Y, DOHI, H, OKAMOTO, S, HIRAOKA, A, GONDO, H, TSUCHIDA, M, O, H, HARADA, M, ASANO, S, JUJI, T, SASAZUKI, T, KATO, S, TAKAKU, F, AKIYAMA, Y, SAO, H, MATSUYAMA, T, KAWA, K, SAKAMAKI, H, NAKAGAWA, S, HIRABAYASHI, N

“…In December 1991, the Japan Marrow Donor Program (JMDP) was established with the cooperation of the Japanese Red Cross and Japan Marrow Donor Foundation under…”
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Overview on the millennium genome project by Takaku, F

“…Millennium genome project had started 2000 April as a national research project. In this project, analysis of single nucleotide polymorphism of human genome…”
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Frequent Mutations in the p53 Gene in Human Myeloid Leukemia Cell Lines by Sugimoto, Koichi, Toyoshima, Hideo, Sakai, Ryuichi, Miyagawa, Kiyoshi, Hagiwara, Koichi, Ishikawa, Fuyuki, Takaku, Fumimaro, Yazaki, Yoshio, Hirai, Hisamaru

“…The p53 gene is currently considered to function as a tumor-suppressor gene in various human malignancies. In hematologic malignancies, alterations in the p53…”
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Atrial natriuretic factor in human blood by YAMAJI, T, ISHIBASHI, M, TAKAKU, F

“…To determine whether atrial natriuretic factor (ANF) is a circulating hormone in men, a radioimmunoassay suitable for the estimation of ANF in human plasma was…”
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Recombinant human granulocyte colony-stimulating factor as an activator of human granulocytes: potentiation of responses triggered by receptor- mediated agonists and stimulation of C3bi receptor expression and adherence by Yuo, A, Kitagawa, S, Ohsaka, A, Ohta, M, Miyazono, K, Okabe, T, Urabe, A, Saito, M, Takaku, F

“…Recombinant human granulocyte colony-stimulating factor (rhG-CSF) enhanced superoxide release and membrane depolarization in parallel in human granulocytes…”
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cDNA cloning of a myosin heavy chain isoform in embryonic smooth muscle and its expression during vascular development and in arteriosclerosis by Kuro-o, M, Nagai, R, Nakahara, K, Katoh, H, Tsai, R C, Tsuchimochi, H, Yazaki, Y, Ohkubo, A, Takaku, F

“…Adult rabbit smooth muscles contain two types of myosin heavy chain (MHC) isoforms, SM1 and SM2 which are generated through alternative RNA splicing from a…”
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Medicine in 21st century: contribution of hematology to advanced medicine by Takaku, F

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Correlation of antibodies to ribosomal P protein with psychosis in patients with systemic lupus erythematosus by Nojima, Y, Minota, S, Yamada, A, Takaku, F, Aotsuka, S, Yokohari, R

“…Ninety one Japanese patients with systemic lupus erythematosus (SLE) were studied to determine the clinical significance of antibodies to ribosomal P protein…”
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Hematology by Takaku, F

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