Search Results - "Takaishi, Mamoru"

Total Synthesis and Determination of the Absolute Configuration of (+)-Intricatetraol by Morimoto, Yoshiki, Okita, Tatsuya, Takaishi, Mamoru, Tanaka, Takeshi

“…A victory for synthesis: The total synthesis of the marine triterpene polyether (+)‐intricatetraol (1) has revealed its absolute configuration, which could not…”
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Total Synthesis and Complete Assignment of the Stereostructure of a Cytotoxic Bromotriterpene Polyether (+)-Aurilol by Morimoto, Yoshiki, Nishikawa, Yoshihiro, Takaishi, Mamoru

“…The plane structure and partial stereochemistry of a cytotoxic bromotriterpene polyether (+)-aurilol (1), isolated from the sea hare Dolabella auricularia,…”
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Two-directional synthesis and stereochemical assignment toward a C2 symmetric oxasqualenoid (+)-intricatetraol by Morimoto, Yoshiki, Takaishi, Mamoru, Adachi, Noriko, Okita, Tatsuya, Yata, Hiromi

“…The asymmetric synthesis of tetraol (+)-3, a degradation product derived from a C2 symmetric oxasqualenoid intricatetraol 1, has been achieved through the…”
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Complete assignment of the stereostructure of a new squalene-derived epoxy tri-THF diol from Spathelia glabrescens by total synthesis by Morimoto, Yoshiki, Takaishi, Mamoru, Iwai, Toshiyuki, Kinoshita, Takamasa, Jacobs, Helen

“…The total assignment of the incomplete stereostructure of a new squalene-derived epoxy tri-tetrahydrofuran (THF) diol ( 2 ) to the structural formula 3 has…”
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Total Synthesis and Determination of the Absolute Configuration of (+)-Intricatetraol by Morimoto, Yoshiki, Okita, Tatsuya, Takaishi, Mamoru, Tanaka, Takeshi

“…Ein Sieg der Synthese: Aus der Totalsynthese des marinen Triterpenpolyethers (+)‐Intricatetraol (1) ließ sich die Absolutkonfiguration ableiten, was mithilfe…”
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Synthesis of BACE1 Inhibitors E2609/E2071 via Oxime–Olefin Cycloaddition Following a Process Risk Mitigation Strategy by Kim, Dae-Shik, Yoshizawa, Kazuhiro, Mitasev, Branko, Schnaderbeck, Matthew, Zhang, Huiming, Omori, Masayuki, Kayano, Akio, Nagai, Mitsuo, Wakasugi, Kazunori, Watanabe, Yuzo, Benayoud, Farid, Suzuki, Yuichi, Motoki, Takafumi, Kaneko, Toshihiko, Takaishi, Mamoru, Ishida, Tasuku, Takeda, Kunitoshi, Kita, Yoichi, Yamamoto, Noboru, Khan, Afzal, Dimopoulos, Paschalis, Farthing, Christopher N, Hall, Adrian, Chanda, Arani, Lu, Lily, Bracke, Markus, Fang, Francis G

“…Process development of E2609 from the preclinical stage to the clinical stage following a process risk mitigation strategy is described here. Key features…”
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Discovery of a New Class of mGluR2 Selective Group II mGluR NAM PET Tracer by Li, Zizhong, Hagiwara, Hiroaki, Takaishi, Mamoru, Teceno, Tyler, Krause, Stephen, sasaki, Takeo, McCracken, Paul, Koyama, Akihiko, Terauchi, Taro

“…Objectives: Metabotropic glutamate receptor subtype 2 (mGluR2) and metabotropic glutamate receptor subtype 3 (mGluR3) are the two members of Group II mGluRs…”
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Total synthesis and determination of the stereochemistry of 2-amino-3-cyclopropylbutanoic acid, a novel plant growth regulator isolated from the mushroom Amanita castanopsidis Hongo by Morimoto, Yoshiki, Takaishi, Mamoru, Kinoshita, Takamasa, Sakaguchi, Kazuhiko, Shibata, Kozo

“…The unknown stereostructure of 2-amino-3-cyclopropylbutanoic acid 1, a novel plant growth regulator isolated from the mushroom Amanita castanopsidis Hongo, was…”
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Total Synthesis and Determination of the Absolute Configuration of (+)‐Intricatetraol by Morimoto, Yoshiki, Okita, Tatsuya, Takaishi, Mamoru, Tanaka, Takeshi

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