Search Results - "Takahashi, Yoriko"
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Aberrant DNA methylation results in altered gene expression in non-alcoholic steatohepatitis-related hepatocellular carcinomas
Published in Journal of cancer research and clinical oncology (01-10-2020)“…Purpose The aim of this study was to investigate DNA methylation alterations in non-alcoholic steatohepatitis (NASH)-related hepatocellular carcinomas (HCCs)…”
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Clinicopathological impacts of DNA methylation alterations on pancreatic ductal adenocarcinoma: prediction of early recurrence based on genome-wide DNA methylation profiling
Published in Journal of cancer research and clinical oncology (01-05-2021)“…Purpose The present study was conducted to clarify the clinicopathological impacts of DNA methylation alterations on pancreatic ductal adenocarcinoma (PDAC)…”
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Synthesis of prodelphinidin B2 3,3′′-digallate using AgOTf-mediated self-condensation
Published in Results in Chemistry (01-12-2024)“…[Display omitted] The Lewis acid mediated self-condensation of an epigallocatechin gallate derivative was examined. We found that AgOTf as a Lewis acid and…”
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Establishment of permutation for cancer risk estimation in the urothelium based on genome-wide DNA methylation analysis
Published in Carcinogenesis (New York) (25-11-2019)“…Abstract The aim of this study was to establish permutation for cancer risk estimation in the urothelium. Twenty-six samples of normal control urothelium…”
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DNA hypermethylation of the ZNF132 gene participates in the clinicopathological aggressiveness of ‘pan-negative’-type lung adenocarcinomas
Published in Carcinogenesis (New York) (25-02-2021)“…Abstract Although some previous studies have examined epigenomic alterations in lung adenocarcinomas, correlations between epigenomic events and genomic driver…”
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Cooperative participation of epigenomic and genomic alterations in the clinicopathological diversity of gastric adenocarcinomas: significance of cell adhesion and epithelial–mesenchymal transition-related signaling pathways
Published in Carcinogenesis (New York) (13-11-2020)“…Abstract The present study was conducted to clarify the cooperative significance of epigenomic and genomic abnormalities during gastric carcinogenesis. Using…”
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Evaluation of photoreceptor-directed fibroblasts derived from retinitis pigmentosa patients with defects in the EYS gene: a possible cost-effective cellular model for mechanism-oriented drug
Published in Stem cell research & therapy (11-04-2022)“…The most common gene responsible for autosomal recessive retinitis pigmentosa (RP) is EYS. The manner of decay of genetically defective EYS gene transcripts…”
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Feasibility of methylome analysis using small amounts of genomic DNA from formalin‐fixed paraffin‐embedded tissue
Published in Pathology international (01-11-2018)Get full text
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Establishment of diagnostic criteria for upper urinary tract urothelial carcinoma based on genome-wide DNA methylation analysis
Published in Epigenetics (01-12-2020)“…The aim of this study was to develop a less invasive and accurate diagnostic system for upper urinary tract urothelial carcinoma (UTUC) based on genome-wide…”
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Alterations of the spindle checkpoint pathway in clinicopathologically aggressive CpG island methylator phenotype clear cell renal cell carcinomas
Published in International journal of cancer (01-12-2015)“…CpG‐island methylator phenotype (CIMP)‐positive clear cell renal cell carcinomas (RCCs) are characterized by accumulation of DNA hypermethylation of CpG…”
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Genes involved in development and differentiation are commonly methylated in cancers derived from multiple organs: a single-institutional methylome analysis using 1007 tissue specimens
Published in Carcinogenesis (New York) (01-03-2017)“…The aim of this study was to clarify the significance of DNA methylation alterations shared by cancers derived from multiple organs. We analyzed…”
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Optical simulation for subsurface nanoglistening
Published in Journal of cataract and refractive surgery (2015)“…Purpose To determine whether subsurface nanoglistening in hydrophobic acrylic intraocular lenses (IOL) diminishes visual performance. Setting Department of…”
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Defining hypo-methylated regions of stem cell-specific promoters in human iPS cells derived from extra-embryonic amnions and lung fibroblasts
Published in PloS one (27-09-2010)“…Human induced pluripotent stem (iPS) cells are currently used as powerful resources in regenerative medicine. During very early developmental stages, DNA…”
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A Strategy for Identification of Oligosaccharide Structures Using Observational Multistage Mass Spectral Library
Published in Analytical chemistry (Washington) (01-08-2005)“…Glycosylation is the most widespread posttranslational modification in eukaryotes; however, the role of oligosaccharides attached to proteins has been little…”
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Human sclera maintains common characteristics with cartilage throughout evolution
Published in PloS one (12-11-2008)“…The sclera maintains and protects the eye ball, which receives visual inputs. Although the sclera does not contribute significantly to visual perception,…”
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Cells of extraembryonic mesodermal origin confer human dystrophin in the Mdx model of duchenne muscular dystrophy
Published in Journal of cellular physiology (01-06-2010)“…Duchenne muscular dystrophy is an X‐linked recessive genetic disease characterized by severe skeletal muscular degeneration. The placenta is considered to be a…”
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Use of a library of mutated Maackia amurensis hemagglutinin for profiling the cell lineage and differentiation
Published in Proteomics (Weinheim) (01-08-2008)“…Thirty-five variant lectins were prepared by mutations of two amino acids within the carbohydrate-recognition domain of Maackia amurensis hemagglutinin (MAH)…”
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Epigenome mapping of human normal purified hepatocytes: personal epigenome variation and genome-epigenome correlation
Published in Epigenomics (01-07-2018)“…The aim of this study was to reveal the epigenome landscape of human normal hepatocytes. Cells purified from partial hepatectomy specimens of Japanese patients…”
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Gremlin enhances the determined path to cardiomyogenesis
Published in PloS one (11-06-2008)“…The critical event in heart formation is commitment of mesodermal cells to a cardiomyogenic fate, and cardiac fate determination is regulated by a series of…”
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