Search Results - "Takahashi, Tomihisa"

p53 deficiency promotes bone regeneration by functional regulation of mesenchymal stromal cells and osteoblasts by Nagashima, Toshimichi, Ninomiya, Tadashi, Nakamura, Yoshiki, Nishimura, Shirabe, Ohashi, Akiko, Aoki, Junya, Mizoguchi, Toshihide, Tonogi, Morio, Takahashi, Tomihisa

“…Introduction The detailed mechanism of the process during bone healing of drill-hole injury has been elucidated, but a crucial factor in regulating drill-hole…”
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Tetrahydrobiopterin Supplementation: Elevation of Tissue Biopterin Levels Accompanied by a Relative Increase in Dihydrobiopterin in the Blood and the Role of Probenecid-Sensitive Uptake in Scavenging Dihydrobiopterin in the Liver and Kidney of Rats by Ohashi, Akiko, Saeki, Yusuke, Harada, Tomonori, Naito, Masako, Takahashi, Tomihisa, Aizawa, Shin, Hasegawa, Hiroyuki

“…Tetrahydrobiopterin (BH4) is an essential cofactor of nitric oxide synthase (NOS) and aromatic amino acid hydroxylases. BH4 and 7,8-dihydrobiopterin (BH2) are…”
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Tension force causes cell cycle arrest at G2/M phase in osteocyte-like cell line MLO-Y4 by Shimizu, Natsuo, Fujiwara, Kyoko, Mayahara, Kotoe, Motoyoshi, Mitsuru, Takahashi, Tomihisa

“…Bone remodelling is the process of bone resorption and formation, necessary to maintain bone structure or for adaptation to new conditions. Mechanical…”
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Action and Contribution of the Iliopsoas and Rectus Femoris as Hip Flexor Agonists Examined with Anatomical Analysis by KUMAZAKI, TOSHIMASA, TAKAHASHI, TOMIHISA, NAKANO, TAKASHI, SAKAI, TATSUO

“…Objectives To evaluate the difference in action between the iliopsoas and rectus femoris muscles in hip flexion by estimating the relative contribution to the…”
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Organic anion transporters, OAT1 and OAT3, are crucial biopterin transporters involved in bodily distribution of tetrahydrobiopterin and exclusion of its excess by Ohashi, Akiko, Mamada, Kaori, Harada, Tomonori, Naito, Masako, Takahashi, Tomihisa, Aizawa, Shin, Hasegawa, Hiroyuki

“…Tetrahydrobiopterin (BH 4 ) is a common coenzyme of phenylalanine-, tyrosine-, and tryptophan hydroxylases, alkylglycerol monooxygenase, and NO synthases…”
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Promyelocytic leukemia zinc finger mediates glucocorticoid-induced cell cycle arrest in the chondroprogenitor cell line ATDC5 by Naito, Masako, Vongsa, Souksavanh, Tsukune, Naoya, Ohashi, Akiko, Takahashi, Tomihisa

“…Glucocorticoids (GCs) affect the proliferation of growth plate chondrocytes. In this study, we investigated the role of the GC-inducible promyelocytic leukemia…”
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Up-regulation of Axin2 by dexamethasone promotes adipocyte differentiation in ROB-C26 mesenchymal progenitor cells by Naito, Masako, Mikami, Yoshikazu, Takagi, Minoru, Takahashi, Tomihisa

“…Dexamethasone (Dex) regulates osteoblastic and adipocytic differentiation in mesenchymal progenitor cells through regulation of Wnt/β-catenin signaling. To…”
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Suppression of lamin A/C by short hairpin RNAs promotes adipocyte lineage commitment in mesenchymal progenitor cell line, ROB-C26 by Naito, Masako, Omoteyama, Kazuki, Mikami, Yoshikazu, Takagi, Minoru, Takahashi, Tomihisa

“…Lamin A/C gene encodes a nuclear membrane protein, and mutations in this gene are associated with diverse degenerative diseases that are linked to premature…”
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Bacitracin Upregulates mbrAB Transcription via mbrCD to Confer Bacitracin Resistance in Streptococcus mutans by Mikami, Yoshikazu, Suzuki, Naoto, Takahashi, Tomihisa, Otsuka, Kichibee, Tsuda, Hiromasa

“…Streptococcus mutans is a bacterial cause of dental caries that is resistant to bacitracin. The aim of this study was to elucidate the mbrABCD-related…”
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The P75 neurotrophin receptor regulates proliferation of the human MG63 osteoblast cell line by Akiyama, Yuko, Mikami, Yoshikazu, Watanabe, Eri, Watanabe, Nobukazu, Toriumi, Taku, Takahashi, Tomihisa, Komiyama, Kazuo, Isokawa, Keitaro, Shimizu, Noriyoshi, Honda, Masaki J.

“…The 75kDa transmembrane protein, p75NTR, is a marker of mesenchymal stem cells (MSCs). Isolated MSCs are capable of differentiating into osteoblasts, but the…”
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The p75 neurotrophin receptor regulates MC3T3-E1 osteoblastic differentiation by Mikami, Yoshikazu, Suzuki, Shinnosuke, Ishii, Yumiko, Watanabe, Nobukazu, Takahashi, Tomihisa, Isokawa, Keitaro, Honda, Masaki J.

“…While the role of p75NTR signaling in the regulation of nerve-related cell growth and survival has been well documented, its actions in osteoblasts are poorly…”
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Dexamethasone promotes DMP1 mRNA expression by inhibiting negative regulation of Runx2 in multipotential mesenchymal progenitor, ROB-C26 by Mikami, Yoshikazu, Takahashi, Tomihisa, Kato, Shigeyuki, Takagi, Minoru

“…Dentin matrix protein 1 (DMP1) is an acidic phosphorylated extracellular protein and essential for mineralization of dentin and bone; however, the precise…”
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Overexpression of Runx2 and MKP-1 Stimulates Transdifferentiation of 3T3-L1 Preadipocytes into Bone-Forming Osteoblasts In Vitro by Takahashi, Tomihisa

“…Runx2, a transcription factor, is essential for osteoblastic differentiation, bone formation, and maintenance. We examined the effect of Runx2 on…”
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Inductive effects of dexamethasone on the gene expression of Cbfa1, Osterix and bone matrix proteins during differentiation of cultured primary rat osteoblasts by Igarashi, Masato, Kamiya, Naoko, Hasegawa, Mitsuharu, Kasuya, Tomohiro, Takahashi, Tomihisa, Takagi, Minoru

“…Runx2/core binding factor alpha 1 (Cbfa1) and Osterix (Osx) are osteoblast-specific transcription factors essential for the development of a mature osteoblast…”
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Autoregulatory mechanism of Runx2 through the expression of transcription factors and bone matrix proteins in multipotential mesenchymal cell line, ROB-C26 by Takahashi, Tomihisa, Kato, Shigeyuki, Suzuki, Naoto, Kawabata, Niki, Takagi, Minoru

“…Runx2 is essential for osteoblast differentiation and gene expression of bone matrix proteins, however, little is known about the mechanism regulating its…”
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Dexamethasone inhibits chondrocyte differentiation by suppression of Wnt/β-catenin signaling in the chondrogenic cell line ATDC5 by Naito, Masako, Ohashi, Akiko, Takahashi, Tomihisa

“…Glucocorticoids (GCs) regulate proliferation and differentiation in cultured mesenchymal cells through the modulation of various molecules. However, the…”
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Self-introduction and myambitions to the research by Takahashi, Tomihisa

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Lamin A overexpression promotes osteoblast differentiation and calcification in the MC3T3-E1 preosteoblastic cell line by Tsukune, Naoya, Naito, Masako, Kubota, Tatsuya, Ozawa, Yasumasa, Nagao, Mayu, Ohashi, Akiko, Sato, Shuichi, Takahashi, Tomihisa

“…Lamin A/C is a component of the nuclear lamina, which is involved in cellular proliferation and differentiation. However, the mechanism by which lamin A…”
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Forced expression of mouse progerin attenuates the osteoblast differentiation interrupting [beta]-catenin signal pathway in vitro by Tsukune, Naoya, Naito, Masako, Ohashi, Akiko, Ninomiya, Tadashi, Sato, Shuichi, Takahashi, Tomihisa

“…Nuclear protein, lamin A, which is a component of inner membrane on nucleoplasm, plays a role in nuclear formation and cell differentiation. The expression of…”
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Forced expression of mouse progerin attenuates the osteoblast differentiation interrupting β-catenin signal pathway in vitro by Tsukune, Naoya, Naito, Masako, Ohashi, Akiko, Ninomiya, Tadashi, Sato, Shuichi, Takahashi, Tomihisa

“…Nuclear protein, lamin A, which is a component of inner membrane on nucleoplasm, plays a role in nuclear formation and cell differentiation. The expression of…”
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