Search Results - "Takahashi, Katsu"
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Mitochondrial function provides instructive signals for activation-induced B-cell fates
Published in Nature communications (10-04-2015)“…During immune reactions, functionally distinct B-cell subsets are generated by stochastic processes, including class-switch recombination (CSR) and plasma cell…”
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Unique pattern of dietary adaptation in the dentition of Carnivora: its advantage and developmental origin
Published in Proceedings of the Royal Society. B, Biological sciences (15-06-2016)“…Carnivora is a successful taxon in terms of dietary diversity. We investigated the dietary adaptations of carnivoran dentition and the developmental background…”
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Local application of Usag-1 siRNA can promote tooth regeneration in Runx2-deficient mice
Published in Scientific reports (01-07-2021)“…Runt-related transcription factor 2 (Runx2 )-deficient mice can be used to model congenital tooth agenesis in humans. Conversely, uterine…”
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Novel MSX1 frameshift mutation in a Japanese family with nonsyndromic oligodontia
Published in Human genome variation (20-07-2021)“…Congenital tooth agenesis is a common anomaly in humans. We investigated the etiology of human tooth agenesis by exome analysis in Japanese patients, and found…”
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A novel LRP6 variant in a Japanese family with oligodontia
Published in Human genome variation (20-07-2021)“…Congenital tooth agenesis is a common anomaly in human development. We performed exome sequence analysis of genomic DNA collected from Japanese patients with…”
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Development of tooth regenerative medicine strategies by controlling the number of teeth using targeted molecular therapy
Published in Inflammation and Regeneration (01-09-2020)“…Analysis of various genetically modified mice, with supernumerary teeth, has revealed the following two intrinsic molecular mechanisms that increase the number…”
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Mastication and risk for diabetes in a Japanese population: a cross-sectional study
Published in PloS one (05-06-2013)“…Associations between mastication and insufficient nutrient intake, obesity, and glucose metabolism have been shown in previous studies. However, the…”
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Antagonistic Functions of USAG-1 and RUNX2 during Tooth Development
Published in PloS one (12-08-2016)“…Supernumerary teeth and tooth agenesis are common morphological anomalies in humans. We previously obtained evidence that supernumerary maxillary incisors form…”
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Interactions between BMP-7 and USAG-1 (uterine sensitization-associated gene-1) regulate supernumerary organ formations
Published in PloS one (09-05-2014)“…Bone morphogenetic proteins (BMPs) are highly conserved signaling molecules that are part of the transforming growth factor (TGF)-beta superfamily, and…”
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ITGA3 and ITGB4 expression biomarkers estimate the risks of locoregional and hematogenous dissemination of oral squamous cell carcinoma
Published in BMC cancer (05-09-2013)“…Molecular biomarkers are essential for monitoring treatment effects, predicting prognosis, and improving survival rate in oral squamous cell carcinoma. This…”
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An anti-peptide monoclonal antibody recognizing the tobacco etch virus protease-cleavage sequence and its application to a tandem tagging system
Published in Protein expression and purification (01-07-2018)“…Peptide-based affinity tags are commonly used in recombinant production/purification of proteins, and are often preceded or followed by a protease recognition…”
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Gender differences in morphological and functional outcomes after mandibular setback surgery
Published in Journal of cranio-maxillo-facial surgery (01-06-2018)“…The aim of this study was to examine and compare morphological and functional outcomes after either isolated mandibular setback or bimaxillary surgery in males…”
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Risk of osteomyelitis of the jaw induced by oral bisphosphonates in patients taking medications for osteoporosis: A hospital-based cohort study in Japan
Published in Bone (New York, N.Y.) (01-11-2012)“…Abstract Oral bisphosphonates (BPs) represent the first line of prevention and treatment for osteoporosis. However, several studies have reported osteonecrosis…”
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Methotrexate-related osteonecrosis of the jaw: Report of two cases
Published in Journal of oral and maxillofacial surgery, medicine, and pathology (01-11-2017)“…Although methotrexate (MTX) is widely used to treat malignancies and autoimmune diseases, it is associated with a range of adverse effects. We report the cases…”
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WNT10A variants isolated from Japanese patients with congenital tooth agenesis
Published in Human genome variation (09-11-2017)“…It has been reported that dozens of WNT10A variants are associated with human isolated tooth agenesis, however, little is known about the precise phenotypes…”
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Recent Clinical Evidence in Bisphosphonate-related Osteomyelitis of the Jaw: Focus on Risk, Prevention and Treatment
Published in Reviews on recent clinical trials (31-05-2014)“…Bisphosphonates (BPs) are widely used for the treatment of a range of conditions involving bone, such as osteoporosis and bone metastases of cancer, and their…”
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Enhanced BMP signaling results in supernumerary tooth formation in USAG-1 deficient mouse
Published in Biochemical and biophysical research communications (16-05-2008)“…Uterine sensitization associated gene-1 (USAG-1) is a BMP antagonist, and also modulates Wnt signaling. We previously reported that USAG-1 deficient mice have…”
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Increased risk of temporomandibular joint closed lock: a case-control study of ANKH polymorphisms
Published in PloS one (07-10-2011)“…This study aimed to carry out a histological examination of the temporomandibular joint (TMJ) in ank mutant mice and to identify polymorphisms of the human…”
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Risk factors and indices of osteomyelitis of the jaw in osteoporosis patients: results from a hospital-based cohort study in Japan
Published in PloS one (01-11-2013)“…Several studies have reported osteomyelitis of the jaw (OMJ) as a side effect of bisphosphonates (BPs), and the risk of oral BPs has been recently clarified…”
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