Search Results - "Takagi, Hiroshi"

Proline as a stress protectant in yeast: physiological functions, metabolic regulations, and biotechnological applications by Takagi, Hiroshi

“…Proline is an important amino acid in terms of its biological functions and biotechnological applications. In response to osmotic stress, proline is…”
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Enhancement of lysine biosynthesis confers high-temperature stress tolerance to Escherichia coli cells by Isogai, Shota, Takagi, Hiroshi

“…Lysine, a nutritionally important amino acid, is involved in adaptation and tolerance to environmental stresses in various organisms. Previous studies reported…”
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purine metabolite allantoin enhances abiotic stress tolerance through synergistic activation of abscisic acid metabolism by WATANABE, SHUNSUKE, MATSUMOTO, MAYUMI, HAKOMORI, YUKI, TAKAGI, HIROSHI, SHIMADA, HIROSHI, SAKAMOTO, ATSUSHI

“…Purine catabolism is regarded as a housekeeping function that remobilizes nitrogen for plant growth and development. However, emerging evidence suggests that…”
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Proline accumulation protects Saccharomyces cerevisiae cells in stationary phase from ethanol stress by reducing reactive oxygen species levels by Takagi, Hiroshi, Taguchi, Junpei, Kaino, Tomohiro

“…During fermentation processes, Saccharomyces cerevisiae cells are exposed to multiple stresses, including a high concentration of ethanol that represents…”
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Molecular mechanism of ethanol fermentation inhibition via protein tyrosine nitration of pyruvate decarboxylase by reactive nitrogen species in yeast by Eknikom, Supapid, Nasuno, Ryo, Takagi, Hiroshi

“…Protein tyrosine nitration (PTN), in which tyrosine (Tyr) residues on proteins are converted into 3-nitrotyrosine (NT), is one of the post-translational…”
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Detection system of the intracellular nitric oxide in yeast by HPLC with a fluorescence detector by Nasuno, Ryo, Shino, Seiya, Yoshikawa, Yuki, Yoshioka, Natsuko, Sato, Yuichi, Kamiya, Kohei, Takagi, Hiroshi

“…Nitric oxide (NO) is an important signaling molecule involved in various biological phenomena in many organisms. The physiological functions and metabolism of…”
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Spontaneous Attenuation of Alcoholic Fermentation via the Dysfunction of Cyc8p in Saccharomyces cerevisiae by Watanabe, Daisuke, Kumano, Maika, Sugimoto, Yukiko, Takagi, Hiroshi

“…A cell population characterized by the release of glucose repression and known as [ ] emerges spontaneously in the yeast . This study revealed that the [ ]…”
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Diagnosis and treatment of autoimmune and IgG4-related hypophysitis: clinical guidelines of the Japan Endocrine Society by Takagi, Hiroshi, Iwama, Shintaro, Sugimura, Yoshihisa, Takahashi, Yutaka, Oki, Yutaka, Akamizu, Takashi, Arima, Hiroshi

“…Hypophysitis, which is often accompanied by pituitary dysfunction, is classified into several subtypes based on the cause, histology, and the location of…”
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Design of a Full‐Consensus Glutamate Decarboxylase and Its Application to GABA Biosynthesis by Takagi, Hiroshi, Kozuka, Kohei, Mimura, Kenta, Nakano, Shogo, Ito, Sohei

“…Glutamate decarboxylase (GAD) catalyses the decarboxylation of L‐glutamate to gamma‐aminobutyric acid (GABA). Improvement of the enzymatic properties of GAD is…”
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Improvement of Fusel Alcohol Production by Engineering of the Yeast Branched-Chain Amino Acid Aminotransaminase by Koonthongkaew, Jirasin, Ploysongsri, Nontawat, Toyokawa, Yoichi, Ruangpornvisuti, Vithaya, Takagi, Hiroshi

“…Branched-chain higher alcohols (BCHAs), or fusel alcohols, including isobutanol, isoamyl alcohol, and active amyl alcohol, are useful compounds in several…”
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Yeast prion-based metabolic reprogramming induced by bacteria in fermented foods by Watanabe, Daisuke, Takagi, Hiroshi

“…ABSTRACT Microbial communities of yeast and bacterial cells are often observed in the manufacturing processes of fermented foods and drinks, such as sourdough…”
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Intracellular production of reactive oxygen species and a DAF-FM-related compound in Aspergillus fumigatus in response to antifungal agent exposure by Oiki, Sayoko, Nasuno, Ryo, Urayama, Syun-ichi, Takagi, Hiroshi, Hagiwara, Daisuke

“…Fungi are ubiquitously present in our living environment and are responsible for crop and infectious diseases. Developing new antifungal agents is constantly…”
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Downregulation of the broad-specificity amino acid permease Agp1 mediated by the ubiquitin ligase Rsp5 and the arrestin-like protein Bul1 in yeast by Tanahashi, Ryoya, Matsushita, Tomonori, Nishimura, Akira, Takagi, Hiroshi

“…Most of plasma membrane transporters are downregulated by ubiquitination-dependent endocytosis to avoid the excess uptake of their substrates. In Saccharomyces…”
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Autologous CD34+ Cell Therapy for Ischemic Tissue Repair by Sietsema, William K., Kawamoto, Atsuhiko, Takagi, Hiroshi, Losordo, Douglas W.

“…In 1997, the seminal manuscript by Asahara, Murohara, Isner et al outlined the evidence for the existence of circulating, bone marrow-derived cells capable of…”
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Arginine inhibits Saccharomyces cerevisiae biofilm formation by inducing endocytosis of the arginine transporter Can1 by Nishimura, Akira, Nakagami, Kazuki, Kan, Kyoyuki, Morita, Fumika, Takagi, Hiroshi

“…ABSTRACT Biofilms are formed by the aggregation of microorganisms into multicellular structures that adhere to surfaces. Biofilm formation by yeast is a…”
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Metabolic Engineering of Saccharomyces cerevisiae for Astaxanthin Production and Oxidative Stress Tolerance by Ukibe, Ken, Hashida, Keisuke, Yoshida, Nobuyuki, Takagi, Hiroshi

“…The red carotenoid astaxanthin possesses higher antioxidant activity than other carotenoids and has great commercial potential for use in the aquaculture,…”
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The analytical method to identify the nitrogen source for nitric oxide synthesis by Nasuno, Ryo, Yoshikawa, Yuki, Takagi, Hiroshi

“…Nitric oxide (NO) is a ubiquitous signaling molecule synthesized from various nitrogen sources. An analytical method to identify a nitrogen source for NO…”
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The arginine transporter Can1 negatively regulates biofilm formation in yeasts by Nishimura, Akira, Tanahashi, Ryoya, Nakagami, Kazuki, Morioka, Yuto, Takagi, Hiroshi

“…The arginine transporter Can1 is a multifunctional protein of the conventional yeast . Apart from facilitating arginine uptake, Can1 plays a pivotal role in…”
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Allantoin, a stress-related purine metabolite, can activate jasmonate signaling in a MYC2-regulated and abscisic acid-dependent manner by Takagi, Hiroshi, Ishiga, Yasuhiro, Watanabe, Shunsuke, Konishi, Tomokazu, Egusa, Mayumi, Akiyoshi, Nobuhiro, Matsuura, Takakazu, Mori, Izumi C., Hirayama, Takashi, Kaminaka, Hironori, Shimada, Hiroshi, Sakamoto, Atsushi

“…Allantoin is a metabolic intermediate of purine catabolism that often accumulates in stressed plants. Recently, we used Arabidopsis knockout mutants (aln) of…”
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Evaluation of postoperative orientation of the knee and ankle joint after open wedge high tibial osteotomy by Kawashima, Fumiyoshi, Takagi, Hiroshi

“…BackgroundCases with varus knee osteoarthritis (OA) often present concomitant ankle joint deformity and poor tibial plafond inclination (TPI) in the coronal…”
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