Search Results - "Takagi, Akinori"
-
1
Fluorouracil uptake in triple‐negative breast cancer cells: Negligible contribution of equilibrative nucleoside transporters 1 and 2
Published in Biopharmaceutics & drug disposition (01-03-2021)“…Equilibrative nucleoside transporters (ENTs) 1 and 2 reportedly accept fluorouracil as a substrate. Here, we evaluated ENT1/2 expression at the messenger RNA…”
Get full text
Journal Article -
2
Contribution of equilibrative nucleoside transporter (ENT) 2 to fluorouracil transport in rat placental trophoblast cells
Published in Drug metabolism and pharmacokinetics (01-04-2017)“…Fluorouracil is used for treatment of breast cancer even in pregnant women, except during fetal organogenesis. The purpose of this study was to clarify the…”
Get full text
Journal Article -
3
深層学習を用いた薬局実務実習の支援必要度の早期予測
Published in YAKUGAKU ZASSHI (01-08-2023)“…「緒言」薬学教育制度は, 2006年度から医療技術の高度化, 医薬分業の進展等に伴い, 高い資質を持つ薬剤師養成のために, 学部の修業年限が4年から6年に延長された(学校教育法 2004年5月21日公布). 6年に延長されたことで実務実習の拡充,…”
Get full text
Journal Article -
4
Hepatocyte growth factor suppresses the anticancer effect of irinotecan by decreasing the level of active metabolite in HepG2 cells
Published in Biochemical pharmacology (01-12-2011)“…In the liver, carboxylesterase (CES) converts irinotecan (CPT-11) to its active metabolite SN-38, which exerts anticancer effects. SN-38 is metabolized to an…”
Get full text
Journal Article -
5
Proton-coupled erythromycin antiport at rat blood-placenta barrier
Published in Drug metabolism and disposition (01-09-2010)“…The aim of the present study was to characterize the mechanism of erythromycin transport at the blood-placenta barrier, using TR-TBT 18d-1 cells as a model of…”
Get full text
Journal Article -
6
Development of a New Scholastic Program for Medication Counseling Practice in Preclinical Training, Constructed for Junior Students by Senior Students Based on Their Experiences of On-site Practice
Published in YAKUGAKU ZASSHI (2017)“…Long-term practical on-site training, based on the Model Core Curriculum for Pharmaceutical Education, is a core program of the 6-year course of pharmaceutical…”
Get full text
Journal Article -
7
Early Prediction of Support Necessity for Pharmacy Clinical Internship Using Deep Learning
Published in YAKUGAKU ZASSHI (01-01-2023)“…The duration of undergraduate study was extended in 2006 to six years for pharmaceutical education aimed at training highly qualified pharmacists. Clinical…”
Get full text
Journal Article -
8
学生のニーズに基づき学生主体で構築した新たなアドバンスト服薬指導事前実習の実施とその評価
Published in YAKUGAKU ZASSHI (01-11-2017)“…「緒言」薬学教育モデル・コアカリキュラムではコミュニケーションに関する到達目標(specific behavioral objectives;SBO)が定められており, 「A 全学年を通して:ヒューマニズムについて学ぶ」の【コミュニケーション】として「1…”
Get full text
Journal Article -
9
Prexasertib increases the sensitivity of pancreatic cancer cells to gemcitabine and S‑1
Published in Oncology reports (01-02-2020)“…Our previous study demonstrated that gemcitabine (GEM), S‑1, and a combination of GEM and S‑1 (GS) induced S‑phase arrest and increased the phosphorylation of…”
Get full text
Journal Article -
10
-
11
Circadian susceptibility rhythm to neuroleptics: tetrabenazine
Published in Psychopharmacology (01-01-1977)“…In order to clarify the influences of situational factors on the effects of psychotropic drugs, the sedative effects of tetrabenazine after injection at…”
Get full text
Journal Article -
12
Tourism Local Community System Using LOD
Published in 2016 10th International Conference on Complex, Intelligent, and Software Intensive Systems (CISIS) (01-07-2016)“…This paper presents a new tourism local community system based on the LOD (Linked Open Data). In this study, the tourism-related data are converted into the…”
Get full text
Conference Proceeding -
13
Studies on circadian susceptibility rhythm to haloperidol (author's transl)
Published in Nihon yakurigaku zasshi (01-01-1978)“…Rats were given haloperidol in a variety of doses and time combinations and the sedation period were then measured. A clear-cut daily fluctuation in the…”
Get more information
Journal Article -
14
Chronopharmacological study of neuroleptics. II. Circadian susceptibility rhythm to chlorpromazine
Published in Psychopharmacology (15-06-1978)“…In order to study differences in the effect of the neuroleptics due to time of administration, rats were administered chlorpromazine (CPZ) in a variety of…”
Get full text
Journal Article -
15
Circadian susceptibility rhythm to haloperidol
Published in Japanese journal of pharmacology (1978)Get full text
Journal Article -
16
Studies on diurnal fluctuation of sedative effect of tetrabenazine
Published in Japanese journal of pharmacology (1974)Get full text
Journal Article -
17
Chronopharmacological studies of neuroleptics
Published in Current developments in psychopharmacology (1981)“…Studies were carried out to clarify the mechanism of appearance and the laws controlling the appearance of such phenomena as circadian fluctuation in the…”
Get more information
Journal Article