Search Results - "Tajnik, Mojca"

Direct Competition between hnRNP C and U2AF65 Protects the Transcriptome from the Exonization of Alu Elements by Zarnack, Kathi, König, Julian, Tajnik, Mojca, Martincorena, Iñigo, Eustermann, Sebastian, Stévant, Isabelle, Reyes, Alejandro, Anders, Simon, Luscombe, Nicholas M., Ule, Jernej

“…There are ∼650,000 Alu elements in transcribed regions of the human genome. These elements contain cryptic splice sites, so they are in constant danger of…”
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Therapeutic activity of modified U1 core spliceosomal particles by Rogalska, Malgorzata Ewa, Tajnik, Mojca, Licastro, Danilo, Bussani, Erica, Camparini, Luca, Mattioli, Chiara, Pagani, Franco

“…Modified U1 snRNAs bound to intronic sequences downstream of the 5′ splice site correct exon skipping caused by different types of mutations. Here we evaluate…”
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Molecular Basis and Therapeutic Strategies to Rescue Factor IX Variants That Affect Splicing and Protein Function by Tajnik, Mojca, Rogalska, Malgorzata Ewa, Bussani, Erica, Barbon, Elena, Balestra, Dario, Pinotti, Mirko, Pagani, Franco

“…Mutations that result in amino acid changes can affect both pre-mRNA splicing and protein function. Understanding the combined effect is essential for correct…”
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Optimization of rAAV capture step purification using SO3 monolith chromatography by Bažec, Kaja, Krašna, Mirjam, Mihevc, Andrej, Leskovec, Maja, Štrancar, Aleš, Tajnik Sbaizero, Mojca

“…Adeno‐associated virus (AAV) vectors are crucial tools for gene therapy applications. As AAVs are administered in vivo, stringent purity requirements must be…”
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Identifying Novel Glioma-Associated Noncoding RNAs by Their Expression Profiles by Matos, Boštjan, Popović, Mara, Boštjančič, Emanuela, Tajnik, Mojca, Matjašič, Alenka, Glavač, Damjan

“…Long noncoding RNAs (lncRNAs) and microRNAs (miRNAs) play a significant role in cancer development as regulators of protein-coding genes. Their dysregulation…”
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iCLIP: Protein–RNA interactions at nucleotide resolution by Huppertz, Ina, Attig, Jan, D’Ambrogio, Andrea, Easton, Laura E., Sibley, Christopher R., Sugimoto, Yoichiro, Tajnik, Mojca, König, Julian, Ule, Jernej

“…RNA-binding proteins (RBPs) are key players in the post-transcriptional regulation of gene expression. Precise knowledge about their binding sites is therefore…”
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Intergenic Alu exonisation facilitates the evolution of tissue-specific transcript ends by Tajnik, Mojca, Vigilante, Alessandra, Braun, Simon, Hänel, Heike, Luscombe, Nicholas M, Ule, Jernej, Zarnack, Kathi, König, Julian

“…The 3' untranslated regions (3' UTRs) of transcripts serve as important hubs for posttranscriptional gene expression regulation. Here, we find that the…”
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Clinical and electrophysiology findings in Slovene patients with Leber hereditary optic neuropathy by Jarc-Vidmar, Martina, Tajnik, Mojca, Brecelj, Jelka, Fakin, Ana, Sustar, Maja, Naji, Mateja, Stirn-Kranjc, Branka, Glavač, Damjan, Hawlina, Marko

“…Background To report clinical and electrophysiology findings in Slovene patients with Leber hereditary optic neuropathy (LHON). Methods Eight patients with…”
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BBC3 is down-regulated with increased tumor size independently of p53 expression in head and neck cancer by Tajnik, Mojca, Stražišar, Mojca, Volavšek, Metka, Boštjančič, Emanuela, Glavač, Damjan

“…The study focuses on BBC3 gene expression in primary head and neck squamous cell carcinomas (HNSCC) in relation to pTNM classification. We used quantitative…”
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