Search Results - "Tajima, Takeshi"
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Reverse Genetics System for a Human Group A Rotavirus
Published in Journal of virology (06-01-2020)“…Group A rotavirus (RV) is a major cause of acute gastroenteritis in infants and young children worldwide. Recently, we established an entirely plasmid-based…”
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Etiology of Acute Otitis Media and Characterization of Pneumococcal Isolates after Introduction of 13-Valent Pneumococcal Conjugate Vaccine in Japanese Children
Published in The Pediatric infectious disease journal (01-06-2018)“…BACKGROUND:Acute otitis media (AOM) is a leading cause of childhood morbidity and antibiotic prescriptions. We examined etiologic changes in AOM after…”
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3
Rapid Effectiveness of Minocycline or Doxycycline Against Macrolide-Resistant Mycoplasma pneumoniae Infection in a 2011 Outbreak Among Japanese Children
Published in Clinical infectious diseases (15-12-2012)“…Background. Mycoplasma pneumoniae is a major pathogen causing community-acquired pneumonia in children and young adults. Outbreaks typically occur at intervals…”
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Capmatinib in Japanese patients with MET exon 14 skipping–mutated or MET‐amplified advanced NSCLC: GEOMETRY mono‐1 study
Published in Cancer science (01-04-2021)“…MET mutations leading to exon 14 skipping (METΔex14) are strong molecular drivers for non–small‐cell lung cancer (NSCLC). Capmatinib is a highly potent,…”
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Phase I study of single‐agent ribociclib in Japanese patients with advanced solid tumors
Published in Cancer science (01-01-2018)“…The cyclin D‐CDK4/6‐INK4‐Rb pathway is frequently dysregulated in cancers. Ribociclib, an orally available, selective CDK4/6 inhibitor, showed preliminary…”
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6
Sequence Type Changes Associated with Decreasing Macrolide-Resistant Mycoplasma pneumoniae, Japan
Published in Emerging infectious diseases (01-09-2020)“…We compared sequence types (STs) of Mycoplasma pneumoniae isolates from Japan during 2002-2019. ST3 and ST14 dominated during 2002-2016, and ST7 and ST33…”
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Killing kinetics of minocycline, doxycycline and tosufloxacin against macrolide-resistant Mycoplasma pneumoniae
Published in International journal of antimicrobial agents (01-08-2017)“…Highlights • Macrolide-resistant Mycoplasma pneumoniae (MRMP) infections are increasing worldwide. • Treatment of MRMP poses particular problems in paediatrics…”
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Hematologic recovery induced by eltrombopag in Japanese patients with aplastic anemia refractory or intolerant to immunosuppressive therapy
Published in International journal of hematology (01-08-2019)“…Eltrombopag, an oral thrombopoietin-receptor agonist, stimulates hematopoiesis in patients with acquired aplastic anemia (AA) and has higher exposure in…”
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Eltrombopag in Combination with Rabbit Anti-thymocyte Globulin/Cyclosporine A in Immunosuppressive Therapy-naïve Patients with Aplastic Anemia in Japan
Published in Internal Medicine (15-04-2021)“…Objective In Japan, immunosuppressive therapy (IST) with anti-thymocyte globulin (ATG), and cyclosporine A (CsA) is the standard of care in patients with…”
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Phase I study of the antiprogrammed cell death‐1 Ab spartalizumab (PDR001) in Japanese patients with advanced malignancies
Published in Cancer science (01-02-2021)“…Spartalizumab is a humanized IgG4/κ mAb directed against human programmed cell death‐1 (PD‐1). In this phase I study, we investigated safety, pharmacokinetics,…”
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A Possible Protective Effect of the 'Cam Deformity' on Femoral Neck Fracture: The Relationship between Hip Morphology and the Types of Hip Fracture
Published in Acta medica Okayama (01-06-2020)“…We retrospectively evaluated the cases of 169 hip fracture patients, their previous fractures, and the contralateral hip joint's morphology. A history of…”
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Nationwide surveillance of bacterial pathogens isolated from children conducted by the surveillance committee of Japanese Society of Chemotherapy, the Japanese Association for Infectious Diseases, and the Japanese Society for Clinical Microbiology in 2017: General overview of pathogenic antimicrobial susceptibility
Published in Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy (01-02-2021)“…A nationwide surveillance of the antimicrobial susceptibility of pediatric patients to bacterial pathogens was conducted by Japanese Society of Chemotherapy,…”
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Pediatric community-acquired pneumonia treated with a three-day course of tebipenem pivoxil
Published in Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy (01-05-2017)“…Abstract We evaluated the efficacy and safety of a 3-day treatment regimen of tebipenem pivoxil for pediatric community-acquired pneumonia. Tebipenem pivoxil…”
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Nationwide survey of the development of drug-resistant pathogens in the pediatric field in 2007 and 2010: drug sensitivity of Streptococcus pneumoniae in Japan (second report)
Published in Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy (2013)“…Abstract We previously conducted nationwide surveillance of Streptococcus pneumoniae in 2000–2001 (period 1) and 2004 (period 2) and reported the findings…”
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Real-time diagnostic analysis of MinION™-based metagenomic sequencing in clinical microbiology evaluation: a case report
Published in JA clinical reports (19-03-2019)Get full text
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Phase I, multicenter, open‐label, dose‐escalation study of sonidegib in Asian patients with advanced solid tumors
Published in Cancer science (01-10-2016)“…Sonidegib is a selective inhibitor of Smoothened receptor, which is a key regulator of the Hedgehog signaling pathway. The purpose of this study was to…”
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Phase I study of panobinostat and 5-azacitidine in Japanese patients with myelodysplastic syndrome or chronic myelomonocytic leukemia
Published in International journal of hematology (2018)“…The current therapy for high-risk myelodysplastic syndrome (MDS) involves repeated cycles of the DNA demethylating agent 5-azacitidine (5-Aza), but combination…”
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Emergence of Macrolide-Resistant Mycoplasma pneumoniae with a 23S rRNA Gene Mutation
Published in Antimicrobial Agents and Chemotherapy (01-06-2005)“…ERRATUM ( vol. 49 , p. 3100 ) Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg…”
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Everolimus for advanced pancreatic neuroendocrine tumours: a subgroup analysis evaluating Japanese patients in the RADIANT-3 trial
Published in Japanese journal of clinical oncology (01-10-2012)“…Everolimus, an inhibitor of the mammalian target of rapamycin, has recently demonstrated efficacy and safety in a Phase III, double-blind, randomized trial…”
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Simultaneous Detection of Pathogens in Clinical Samples from Patients with Community-Acquired Pneumonia by Real-Time PCR with Pathogen-Specific Molecular Beacon Probes
Published in Journal of Clinical Microbiology (01-04-2006)“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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