Search Results - "Tai, Wai Lydia"
-
1
miRNA-23a/CXCR4 regulates neuropathic pain via directly targeting TXNIP/NLRP3 inflammasome axis
Published in Journal of neuroinflammation (31-01-2018)“…Chemokine CXC receptor 4 (CXCR4) in spinal glial cells has been implicated in neuropathic pain. However, the regulatory cascades of CXCR4 in neuropathic pain…”
Get full text
Journal Article -
2
MG53 anchored by dysferlin to cell membrane reduces hepatocyte apoptosis which induced by ischaemia/reperfusion injury in vivo and in vitro
Published in Journal of cellular and molecular medicine (01-10-2017)“…Hepatic ischaemia/reperfusion (HIR) induces severe damage on hepatocyte cell membrane, which leads to hepatocyte death and the subsequent HIR injury. In this…”
Get full text
Journal Article -
3
Electrical stimulation alters DNA methylation and promotes neurite outgrowth
Published in Journal of cellular biochemistry (01-10-2023)“…Abstract Electrical stimulation (ES) influences neural regeneration and functionality. We here investigate whether ES regulates DNA demethylation, a critical…”
Get full text
Journal Article -
4
Flurbiprofen axetil attenuates cerebral ischemia/reperfusion injury by reducing inflammation in a rat model of transient global cerebral ischemia/reperfusion
Published in Bioscience reports (31-08-2018)“…Ischemic stroke has been ranked as the second cause of death in patients worldwide. Inflammation which is activated during cerebral ischemia/reperfusion (I/R)…”
Get full text
Journal Article -
5
Epigenetic Regulation of Optic Nerve Development, Protection, and Repair
Published in International journal of molecular sciences (10-08-2022)“…Epigenetic factors are known to influence tissue development, functionality, and their response to pathophysiology. This review will focus on different types…”
Get full text
Journal Article -
6
Suppression of Pax2 Attenuates Allodynia and Hyperalgesia through ET-1–ETAR–NFAT5 Signaling in a Rat Model of Neuropathic Pain
Published in Neuroscience (01-08-2018)“…•A novel functional regulatory mechanism of Endothelin-1 axis in neuropathic pain processing is proposed.•Suppression of paired box gene 2 inhibits…”
Get full text
Journal Article -
7
Central administration of C-X-C chemokine receptor type 4 antagonist alleviates the development and maintenance of peripheral neuropathic pain in mice
Published in PloS one (13-08-2014)“…To explore the roles of C-X-C chemokine receptor type 4 (CXCR4) in spinal processing of neuropathic pain at the central nervous system (CNS). Peripheral…”
Get full text
Journal Article -
8
Preservation of vision by transpalpebral electrical stimulation in mice with inherited retinal degeneration
Published in Frontiers in cell and developmental biology (14-08-2024)“…The potential neuroprotective and regenerative properties of electrical stimulation (ES) were studied in rhodopsin knockout mice ( ), a murine model of…”
Get full text
Journal Article -
9
Pro-resolving mediator maresin 1 ameliorates pain hypersensitivity in a rat spinal nerve ligation model of neuropathic pain
Published in Journal of pain research (01-01-2018)“…Pro-resolving mediators (PRMs) are considered as emerging analgesics for chronic pain. Maresin 1 (MaR1) is a newly identified member of PRMs, and recent…”
Get full text
Journal Article -
10
Sex differences in complex regional pain syndrome type I (CRPS-I) in mice
Published in Journal of pain research (01-01-2017)“…Sex differences have been increasingly highlighted in complex regional pain syndrome (CRPS) in clinical practice. In CRPS type I (CRPS-I), although…”
Get full text
Journal Article -
11
Abstract 13603: Inhibition of Exercise-Regulated Long Noncoding RNA SALTe1 Reverses Vascular Aging and Age-Related Cardiac Dysfunction
Published in Circulation (New York, N.Y.) (07-11-2023)“…Abstract only Rationale: Age is a major risk factor for cardiovascular disease. Recent work suggests vascular aging is an important determinant of longevity…”
Get full text
Journal Article -
12
Enriched Environment and Effects on Neuropathic Pain: Experimental Findings and Mechanisms
Published in Pain practice (01-11-2018)“…Neuropathic pain inflicts tremendous biopsychosocial suffering for patients worldwide. However, safe and effective treatment of neuropathic pain is a prominent…”
Get full text
Journal Article -
13
Histone deacetylase 5 (HDAC5) regulates neuropathic pain through SRY-related HMG-box 10 (SOX10)-dependent mechanism in mice
Published in Pain (Amsterdam) (01-03-2018)“…A strong link between histone deacetylases (HDACs) and nociceptive hypersensitivity has been indicated in different pain models. However, the underlying…”
Get full text
Journal Article -
14
Oxidative Stress and Inflammation Interaction in Ischemia Reperfusion Injury: Role of Programmed Cell Death
Published in Oxidative medicine and cellular longevity (01-01-2019)“…Zheng et al. demonstrated that the induction of pyroptotic cell death mediated via nod-like receptor protein-3 (NLRP3) inflammasome is critical in high-fat…”
Get full text
Journal Article -
15
Sex differences in complex regional pain syndrome type I
Published in Journal of pain research (01-01-2017)“…Background: Sex differences have been increasingly highlighted in complex regional pain syndrome (CRPS) in clinical practice. In CRPS type I (CRPS-I), although…”
Get full text
Journal Article -
16
Central Administration of C-X-C Chemokine Receptor Type 4 Antagonist Alleviates the Development and Maintenance of Peripheral Neuropathic Pain in Mice: e104860
Published in PloS one (01-08-2014)“…Aim To explore the roles of C-X-C chemokine receptor type 4 (CXCR4) in spinal processing of neuropathic pain at the central nervous system (CNS). Methods…”
Get full text
Journal Article