Search Results - "Tai, W"
-
1
Adeno-associated virus vector as a platform for gene therapy delivery
Published in Nature reviews. Drug discovery (01-05-2019)“…Adeno-associated virus (AAV) vectors are the leading platform for gene delivery for the treatment of a variety of human diseases. Recent advances in developing…”
Get full text
Journal Article -
2
Constructing Playful Talk through Translanguaging in English Medium Instruction Mathematics Classrooms
Published in Applied linguistics (01-08-2021)“…Abstract Recent studies on English-Medium-Instruction (EMI) classroom interaction have begun to look at the role of translanguaging as a pedagogical practice…”
Get full text
Journal Article -
3
Viral vector platforms within the gene therapy landscape
Published in Signal transduction and targeted therapy (08-02-2021)“…Throughout its 40-year history, the field of gene therapy has been marked by many transitions. It has seen great strides in combating human disease, has given…”
Get full text
Journal Article -
4
Rab18 binds to hepatitis C virus NS5A and promotes interaction between sites of viral replication and lipid droplets
Published in PLoS pathogens (01-08-2013)“…Hepatitis C virus (HCV) is a single-stranded RNA virus that replicates on endoplasmic reticulum-derived membranes. HCV particle assembly is dependent on the…”
Get full text
Journal Article -
5
Improving model–data mismatch for photon‐counting detector model using global and local model parameters
Published in Medical physics (Lancaster) (01-02-2024)“…Background An energy‐discriminating capability of a photon counting detector (PCD) can provide many clinical advantages, but several factors, such as charge…”
Get full text
Journal Article -
6
The role of the phosphatidylinositol 4-kinase PI4KA in hepatitis C virus-induced host membrane rearrangement
Published in PloS one (12-10-2011)“…Hepatitis C virus (HCV), like other positive-sense RNA viruses, replicates on an altered host membrane compartment that has been called the "membranous web."…”
Get full text
Journal Article -
7
Co-Learning in Hong Kong English medium instruction mathematics secondary classrooms: a translanguaging perspective
Published in Language and education (04-05-2021)“…Recent studies on classroom discourse have challenged the traditional classroom role set and emphasised equal contributions from the participants and the…”
Get full text
Journal Article -
8
Oxysterol-Binding Protein Is a Phosphatidylinositol 4-Kinase Effector Required for HCV Replication Membrane Integrity and Cholesterol Trafficking
Published in Gastroenterology (New York, N.Y. 1943) (01-05-2014)“…Background & Aims Positive-sense RNA viruses remodel intracellular membranes to generate specialized membrane compartments for viral replication. Several RNA…”
Get full text
Journal Article -
9
Ex Vivo Liver Resection and Autotransplantation for End-Stage Alveolar Echinococcosis: A Case Series
Published in American journal of transplantation (01-02-2016)“…The role of autotransplantation in end-stage hepatic alveolar echinococcosis (AE) is unclear. We aimed to present our 15-case experience and propose selection…”
Get full text
Journal Article -
10
Wukan: Failed Promises of the Era of Reform and Opening
Published in Critical Asian studies (02-01-2023)Get full text
Journal Article Book Review -
11
Self-inactivating, all-in-one AAV vectors for precision Cas9 genome editing via homology-directed repair in vivo
Published in Nature communications (01-11-2021)“…Adeno-associated virus (AAV) vectors are important delivery platforms for therapeutic genome editing but are severely constrained by cargo limits. Simultaneous…”
Get full text
Journal Article -
12
Identification of cell type specific ACE2 modifiers by CRISPR screening
Published in PLoS pathogens (01-03-2022)“…SARS-CoV-2 infection is initiated by binding of the viral spike protein to its receptor, ACE2, on the surface of host cells. ACE2 expression is heterogeneous…”
Get full text
Journal Article -
13
The use of intercoder reliability in qualitative interview data analysis in science education
Published in Research in science & technological education (03-07-2023)“…Intercoder reliability is a statistic commonly reported by researchers to demonstrate the rigour of coding procedures during data analysis. Its importance is…”
Get full text
Journal Article -
14
Bone-targeting AAV-mediated silencing of Schnurri-3 prevents bone loss in osteoporosis
Published in Nature communications (04-07-2019)“…RNAi-based bone anabolic gene therapy has demonstrated initial success, but many practical challenges are still unmet. Here, we demonstrate that a recombinant…”
Get full text
Journal Article -
15
Degradable RGD-Functionalized 3D-Printed Scaffold Promotes Osteogenesis
Published in Journal of dental research (01-09-2021)“…To establish an ideal microenvironment for regenerating maxillofacial defects, recent research interests have concentrated on developing scaffolds with…”
Get full text
Journal Article -
16
Effect of a High-Fructose Weight-Maintaining Diet on Lipogenesis and Liver Fat
Published in The journal of clinical endocrinology and metabolism (01-06-2015)“…Context: Consumption of high-fructose diets promotes hepatic fatty acid synthesis (de novo lipogenesis [DNL]) and an atherogenic lipid profile. It is unclear…”
Get full text
Journal Article -
17
Identification of candidate molecular markers predicting sensitivity in solid tumors to dasatinib : Rationale for patient selection
Published in Cancer research (Chicago, Ill.) (01-03-2007)“…Dasatinib is a multitargeted kinase inhibitor that was recently approved for the treatment of chronic myelogenous leukemia and Philadelphia chromosome-positive…”
Get full text
Journal Article -
18
The AAV2.7m8 capsid packages a higher degree of heterogeneous vector genomes than AAV2
Published in Gene therapy (01-09-2024)“…Recombinant adeno-associated virus (rAAV) vectors are currently the only proven vehicles for treating ophthalmological diseases through gene therapy. A wide…”
Get full text
Journal Article -
19
Reticulons promote formation of ER-derived double-membrane vesicles that facilitate SARS-CoV-2 replication
Published in The Journal of cell biology (03-07-2023)“…Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the etiologic agent for the global COVID-19 pandemic, triggers the formation of endoplasmic…”
Get full text
Journal Article -
20
The Long-Term Effects of Organophosphates Poisoning as a Risk Factor of CVDs: A Nationwide Population-Based Cohort Study
Published in PloS one (04-09-2015)“…Organophosphorus pesticides are widely used throughout the world. Because of their ease of availability, organophosphorus compounds are commonly used for…”
Get full text
Journal Article