Search Results - "Tai, David"

Nanoarchitectonics for Hybrid and Related Materials for Bio‐Oriented Applications by Ariga, Katsuhiko, Leong, David Tai, Mori, Taizo

“…Atom/molecular‐level controls in nanotechnology are important for the precise placement of components in device applications. Despite many advances,…”
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Nanoarchitectonics beyond Self‐Assembly: Challenges to Create Bio‐Like Hierarchic Organization by Ariga, Katsuhiko, Jia, Xiaofang, Song, Jingwen, Hill, Jonathan P., Leong, David Tai, Jia, Yi, Li, Junbai

“…Incorporation of non‐equilibrium actions in the sequence of self‐assembly processes would be an effective means to establish bio‐like high functionality…”
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Safety, Efficacy, and Pharmacodynamics of Tremelimumab Plus Durvalumab for Patients With Unresectable Hepatocellular Carcinoma: Randomized Expansion of a Phase I/II Study by Kelley, Robin Kate, Sangro, Bruno, Harris, William, Ikeda, Masafumi, Okusaka, Takuji, Kang, Yoon-Koo, Qin, Shukui, Tai, David W-M, Lim, Ho Yeong, Yau, Thomas, Yong, Wei-Peng, Cheng, Ann-Lii, Gasbarrini, Antonio, Damian, Silvia, Bruix, Jordi, Borad, Mitesh, Bendell, Johanna, Kim, Tae-You, Standifer, Nathan, He, Philip, Makowsky, Mallory, Negro, Alejandra, Kudo, Masatoshi, Abou-Alfa, Ghassan K

“…This phase I/II study evaluated tremelimumab (anticytotoxic T-lymphocyte-associated antigen-4 monoclonal antibody) and durvalumab (antiprogrammed death…”
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Engineering Functional Metal Materials at the Atomic Level by Yao, Qiaofeng, Yuan, Xun, Chen, Tiankai, Leong, David Tai, Xie, Jianping

“…With continuous research efforts devoted into synthesis and characterization chemistry of functional nanomaterials in the past decades, the development of…”
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Balancing the Rate of Cluster Growth and Etching for Gram-Scale Synthesis of Thiolate-Protected Au25 Nanoclusters with Atomic Precision by Yuan, Xun, Zhang, Bin, Luo, Zhentao, Yao, Qiaofeng, Leong, David Tai, Yan, Ning, Xie, Jianping

“…We report a NaOH‐mediated NaBH4 reduction method for the synthesis of mono‐, bi‐, and tri‐thiolate‐protected Au25 nanoclusters (NCs) with precise control of…”
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Nanoparticle Density: A Critical Biophysical Regulator of Endothelial Permeability by Tay, Chor Yong, Setyawati, Magdiel Inggrid, Leong, David Tai

“…The integrity of the vasculature system is intrinsically sensitive to a short list of biophysical cues spanning from nano to micro scales. We have earlier…”
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Retooling Cancer Nanotherapeutics’ Entry into Tumors to Alleviate Tumoral Hypoxia by Sun, Xiao, Ni, Nengyi, Ma, Yanling, Wang, Yan, Leong, David Tai

“…Anti‐hypoxia cancer nanomedicine (AHCN) holds exciting potential in improving oxygen‐dependent therapeutic efficiencies of malignant tumors. However, most…”
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Highly Luminescent Thiolated Gold Nanoclusters Impregnated in Nanogel by Goswami, Nirmal, Lin, Fangxiong, Liu, Yanbiao, Leong, David Tai, Xie, Jianping

“…Highly luminescent thiolated gold nanoclusters have been synthesized by “spatially confining” the Au­(I)-thiolate complexes in a biocompatible and…”
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Nanoparticles promote in vivo breast cancer cell intravasation and extravasation by inducing endothelial leakiness by Peng, Fei, Setyawati, Magdiel Inggrid, Tee, Jie Kai, Ding, Xianguang, Wang, Jinping, Nga, Min En, Ho, Han Kiat, Leong, David Tai

“…While most cancer nanomedicine is designed to eliminate cancer, the nanomaterial per se can lead to the formation of micrometre-sized gaps in the blood vessel…”
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Understanding seed-mediated growth of gold nanoclusters at molecular level by Yao, Qiaofeng, Yuan, Xun, Fung, Victor, Yu, Yong, Leong, David Tai, Jiang, De-en, Xie, Jianping

“…The continuous development of total synthesis chemistry has allowed many organic and biomolecules to be produced with known synthetic history–that is, a…”
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From Aggregation-Induced Emission of Au(I)–Thiolate Complexes to Ultrabright Au(0)@Au(I)–Thiolate Core–Shell Nanoclusters by Luo, Zhentao, Yuan, Xun, Yu, Yue, Zhang, Qingbo, Leong, David Tai, Lee, Jim Yang, Xie, Jianping

“…A fundamental understanding of the luminescence of Au–thiolate nanoclusters (NCs), such as the origin of emission and the size effect in luminescence, is…”
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Defect engineered bioactive transition metals dichalcogenides quantum dots by Ding, Xianguang, Peng, Fei, Zhou, Jun, Gong, Wenbin, Slaven, Garaj, Loh, Kian Ping, Lim, Chwee Teck, Leong, David Tai

“…Transition metal dichalcogenide (TMD) quantum dots (QDs) are fundamentally interesting because of the stronger quantum size effect with decreased lateral…”
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Glutathione-Protected Silver Nanoclusters as Cysteine-Selective Fluorometric and Colorimetric Probe by Yuan, Xun, Tay, Yuanqi, Dou, Xinyue, Luo, Zhentao, Leong, David Tai, Xie, Jianping

“…The integration of the unique thiol-Ag chemistry and the specific steric hindrance from the organic layer of fluorescent Ag nanoclusters (AgNCs) was first…”
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Combinational Immunotherapy for Hepatocellular Carcinoma: Radiotherapy, Immune Checkpoint Blockade and Beyond by Lee, Yun Hua, Tai, David, Yip, Connie, Choo, Su Pin, Chew, Valerie

“…The systemic treatment landscape for advanced hepatocellular carcinoma (HCC) has experienced tremendous paradigm shift towards targeting tumor microenvironment…”
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Nanotheranostics - application and further development of nanomedicine strategies for advanced theranostics by Muthu, Madaswamy S, Leong, David Tai, Mei, Lin, Feng, Si-Shen

“…Nanotheranostics is to apply and further develop nanomedicine strategies for advanced theranostics. This review summarizes the various nanocarriers developed…”
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Assembling Defined DNA Nanostructure with Nitrogen‐Enriched Carbon Dots for Theranostic Cancer Applications by Wu, Di, Li, Bang Lin, Zhao, Qianwen, Liu, Qian, Wang, Dong, He, Binfeng, Wei, Zhenghua, Leong, David Tai, Wang, Guansong, Qian, Hang

“…DNA nanostructures as scaffolds for drug delivery, biosensing, and bioimaging are hindered by its vulnerability in physiological settings, less favorable of…”
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Bio-interactive nanoarchitectonics with two-dimensional materials and environments by Shen, Xuechen, Song, Jingwen, Sevencan, Cansu, Leong, David Tai, Ariga, Katsuhiko

“…Like the proposal of nanotechnology by Richard Feynman, the nanoarchitectonics concept was initially proposed by Masakazu Aono. The nanoarchitectonics strategy…”
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Clinical Applications of Carbon Nanomaterials in Diagnostics and Therapy by Loh, Kian Ping, Ho, Dean, Chiu, Gigi Ngar Chee, Leong, David Tai, Pastorin, Giorgia, Chow, Edward Kai‐Hua

“…Nanomaterials have the potential to improve how patients are clinically treated and diagnosed. While there are a number of nanomaterials that can be used…”
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Defect‐Rich Molybdenum Sulfide Quantum Dots for Amplified Photoluminescence and Photonics‐Driven Reactive Oxygen Species Generation by Zhu, Houjuan, Zan, Wenyan, Chen, Wanli, Jiang, Wenbin, Ding, Xianguang, Li, Bang Lin, Mu, Yuewen, Wang, Lei, Garaj, Slaven, Leong, David Tai

“…Transition metal dichalcogenide (TMD) quantum dots (QDs) with defects have attracted interesting chemistry due to the contribution of vacancies to their unique…”
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Materialistic Interfaces with Nucleic Acids: Principles and Their Impact by Li, Bang Lin, Zhang, Hang, Li, Nian Bing, Qian, Hang, Leong, David Tai

“…Mendelian genetics spark the century‐old revolution in genetic engineering. DNA structural engineering may well spark a similar revolution in chemistry. The…”
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