Search Results - "Tahir ul Qamar, Muhammad"
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Vaccinomics to Design a Multi-Epitopes Vaccine for Acinetobacter baumannii
Published in International journal of environmental research and public health (04-05-2022)“…Antibiotic resistance (AR) is the result of microbes' natural evolution to withstand the action of antibiotics used against them. AR is rising to a high level…”
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Structural basis of SARS-CoV-2 3CLpro and anti-COVID-19 drug discovery from medicinal plants
Published in Journal of pharmaceutical analysis (01-08-2020)“…The recent pandemic of coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 has raised global health concerns. The viral 3-chymotrypsin-like cysteine…”
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Identification and Analysis of Micro-Exon Genes in the Rice Genome
Published in International journal of molecular sciences (31-05-2019)“…Micro-exons are a kind of exons with lengths no more than 51 nucleotides. They are generally ignored in genome annotation due to the short length, whereas…”
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Whole Proteome-Based Therapeutic Targets Annotation and Designing of Multi-Epitope-Based Vaccines against the Gram-Negative XDR- Alcaligenes faecalis Bacterium
Published in Vaccines (Basel) (17-03-2022)“…This study involved therapeutic targets mining for the extremely drug-resistant bacterial species called , which is known to infect humans. The infections…”
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Machine learning for synergistic network pharmacology: a comprehensive overview
Published in Briefings in bioinformatics (19-05-2023)“…Abstract Network pharmacology is an emerging area of systematic drug research that attempts to understand drug actions and interactions with multiple targets…”
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Epitope-based peptide vaccine design and target site depiction against Middle East Respiratory Syndrome Coronavirus: an immune-informatics study
Published in Journal of translational medicine (08-11-2019)“…Middle East Respiratory Syndrome Coronavirus (MERS-COV) is the main cause of lung and kidney infections in developing countries such as Saudi Arabia and South…”
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Network Pharmacology Approach for Medicinal Plants: Review and Assessment
Published in Pharmaceuticals (Basel, Switzerland) (04-05-2022)“…Natural products have played a critical role in medicine due to their ability to bind and modulate cellular targets involved in disease. Medicinal plants hold…”
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Computational screening of medicinal plant phytochemicals to discover potent pan-serotype inhibitors against dengue virus
Published in Scientific reports (05-02-2019)“…Emergence of Dengue as one of the deadliest viral diseases prompts the need for development of effective therapeutic agents. Dengue virus (DV) exists in four…”
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In silico design and immunoinformatics analysis of a universal multi-epitope vaccine against monkeypox virus
Published in PloS one (23-05-2023)“…Monkeypox virus (MPXV) outbreaks have been reported in various countries worldwide; however, there is no specific vaccine against MPXV. In this study,…”
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Molecular Docking and Simulation Studies of Antidiabetic Agents Devised from Hypoglycemic Polypeptide-P of Momordica charantia
Published in BioMed research international (2021)“…Diabetes mellitus termed as metabolic disorder is a collection of interlinked diseases and mainly body’s inability to manage glucose level which leads to…”
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Towards A Novel Multi-Epitopes Chimeric Vaccine for Simulating Strong Immune Responses and Protection against Morganella morganii
Published in International journal of environmental research and public health (19-10-2021)“…is one of the main etiological agents of hospital-acquired infections and no licensed vaccine is available against the pathogen. Herein, we designed a…”
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Discovery of Potential Antiviral Compounds against Hendra Virus by Targeting Its Receptor-Binding Protein (G) Using Computational Approaches
Published in Molecules (Basel, Switzerland) (16-01-2022)“…Hendra virus (HeV) belongs to the paramyxoviridae family of viruses which is associated with the respiratory distress, neurological illness, and potential…”
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Current Progress, Applications and Challenges of Multi-Omics Approaches in Sesame Genetic Improvement
Published in International journal of molecular sciences (04-02-2023)“…Sesame is one of the important traditional oil crops in the world, and has high economic and nutritional value. Recently, due to the novel high throughput…”
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Designing of a multi-epitopes-based peptide vaccine against rift valley fever virus and its validation through integrated computational approaches
Published in Computers in biology and medicine (01-02-2022)“…Since its discovery, the Rift Valley Fever virus (RVFV) has been the source of numerous outbreaks in the Arab Peninsulas and Africa, wreaking havoc on humans…”
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Computer-Aided Multi-Epitope Vaccine Design against Enterobacter xiangfangensis
Published in International journal of environmental research and public health (23-06-2022)“…Antibiotic resistance is a global public health threat and is associated with high mortality due to antibiotics’ inability to treat bacterial infections…”
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Designing of a Recombinant Multi-Epitopes Based Vaccine against Enterococcus mundtii Using Bioinformatics and Immunoinformatics Approaches
Published in International journal of environmental research and public health (21-03-2022)“…Enterococcus species are an emerging group of bacterial pathogens that have a significant role in hospital-associated infections and are associated with higher…”
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Advanced network pharmacology study reveals multi-pathway and multi-gene regulatory molecular mechanism of Bacopa monnieri in liver cancer based on data mining, molecular modeling, and microarray data analysis
Published in Computers in biology and medicine (01-07-2023)“…Liver cancer is a malignant tumor that grows on the surface or inside the liver. The leading cause is a viral infection with hepatitis B or C virus. Natural…”
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High-quality reference genome sequences of two coconut cultivars provide insights into evolution of monocot chromosomes and differentiation of fiber content and plant height
Published in Genome Biology (04-11-2021)“…Coconut is an important tropical oil and fruit crop whose evolutionary position renders it a fantastic species for the investigation of the evolution of…”
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Development of a Novel Multi-Epitope Vaccine Against Crimean-Congo Hemorrhagic Fever Virus: An Integrated Reverse Vaccinology, Vaccine Informatics and Biophysics Approach
Published in Frontiers in immunology (16-06-2021)“…Crimean-Congo hemorrhagic fever (CCHF) is a highly severe and virulent viral disease of zoonotic origin, caused by a tick-born CCHF virus (CCHFV). The virus is…”
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Peptide vaccine against chikungunya virus: immuno-informatics combined with molecular docking approach
Published in Journal of translational medicine (27-10-2018)“…Chikungunya virus (CHIKV), causes massive outbreaks of chikungunya infection in several regions of Asia, Africa and Central/South America. Being positive sense…”
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