Search Results - "Taher, Jennifer"

GLP-1 Elicits an Intrinsic Gut-Liver Metabolic Signal to Ameliorate Diet-Induced VLDL Overproduction and Insulin Resistance by Khound, Rituraj, Taher, Jennifer, Baker, Christopher, Adeli, Khosrow, Su, Qiaozhu

“…Perturbations in hepatic lipid and very-low-density lipoprotein (VLDL) metabolism are involved in the pathogenesis of obesity and hepatic insulin resistance…”
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GLP-2 Dysregulates Hepatic Lipoprotein Metabolism, Inducing Fatty Liver and VLDL Overproduction in Male Hamsters and Mice by Taher, Jennifer, Baker, Christopher, Alvares, Danielle, Ijaz, Laraib, Hussain, Mahmood, Adeli, Khosrow

“…Fundamental complications of insulin resistance and type 2 diabetes include the development of nonalcoholic fatty liver disease and an atherogenic fasting…”
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Central Nervous System Regulation of Intestinal Lipoprotein Metabolism by Glucagon-Like Peptide-1 via a Brain–Gut Axis by Farr, Sarah, Baker, Christopher, Naples, Mark, Taher, Jennifer, Iqbal, Jahangir, Hussain, Mahmood, Adeli, Khosrow

“…OBJECTIVE—Intestinal overproduction of atherogenic chylomicron particles postprandially is an important component of diabetic dyslipidemia in insulin-resistant…”
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HLA Variation and SARS-CoV-2 Specific Antibody Response by Wolday, Dawit, Fung, Chun Yiu Jordan, Morgan, Gregory, Casalino, Selina, Frangione, Erika, Taher, Jennifer, Lerner-Ellis, Jordan P

“…Differences in SARS-CoV-2-specific immune responses have been observed between individuals following natural infection or vaccination. In addition to already…”
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Glucagon-Like Peptide 2 (GLP-2) Stimulates Postprandial Chylomicron Production and Postabsorptive Release of Intestinal Triglyceride Storage Pools via Induction of Nitric Oxide Signaling in Male Hamsters and Mice by Hsieh, Joanne, Trajcevski, Karin E, Farr, Sarah L, Baker, Christopher L, Lake, Elizabeth J, Taher, Jennifer, Iqbal, Jahangir, Hussain, Mahmood M, Adeli, Khosrow

“…The intestinal overproduction of apolipoprotein B48 (apoB48)-containing chylomicron particles is a common feature of diabetic dyslipidemia and contributes to…”
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Complex role of autophagy in regulation of hepatic lipid and lipoprotein metabolism by Zamani, Mostafa, Taher, Jennifer, Adeli, Khosrow

“…Discovering new therapeutic interventions to treat lipid and lipoprotein disorders is of great interest and the discovery of autophagy as a regulator of lipid…”
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GLP-1 receptor agonism ameliorates hepatic VLDL overproduction and de novo lipogenesis in insulin resistance by Taher, Jennifer, Baker, Christopher L, Cuizon, Carmelle, Masoudpour, Hassan, Zhang, Rianna, Farr, Sarah, Naples, Mark, Bourdon, Celine, Pausova, Zdenka, Adeli, Khosrow

“…Abstract Background/objectives Fasting dyslipidemia is commonly observed in insulin resistant states and mechanistically linked to hepatic overproduction of…”
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Implementation of serological and molecular tools to inform COVID-19 patient management: protocol for the GENCOV prospective cohort study by Taher, Jennifer, Mighton, Chloe, Chowdhary, Sunakshi, Casalino, Selina, Frangione, Erika, Arnoldo, Saranya, Bearss, Erin, Binnie, Alexandra, Bombard, Yvonne, Borgundvaag, Bjug, Chertkow, Howard, Clausen, Marc, Devine, Luke, Faghfoury, Hanna, Friedman, Steven Marc, Gingras, Anne-Claude, Khan, Zeeshan, Mazzulli, Tony, McGeer, Allison, McLeod, Shelley L, Pugh, Trevor J, Richardson, David, Simpson, Jared, Stern, Seth, Strug, Lisa, Taher, Ahmed, Lerner-Ellis, Jordan

“…IntroductionThere is considerable variability in symptoms and severity of COVID-19 among patients infected by the SARS-CoV-2 virus. Linking host and virus…”
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P733: Comparative analysis of DNA variant classifications between the GENCOV COVID-19 genome study and the ClinVar database by Mahajan, Radhika, Frangione, Erika, Aujla, Navneet, Casalino, Selina, Jayachandran, Lochana, Morgan, Gregory, Young, Juliet, Dickson, Brendan, Arnoldo, Saranya, Bearss, Erin, Binnie, Alexandra, Borgundvaag, Bjug, Clausen, Marc, Dagher, Marc, Devine, Luke, Friedman, Steven, Gingras, Anne-Claude, Khan, Zeeshan, Mazzulli, Tony, McLeod, Shelley, Mighton, Chloe, Pugh, Trevor, Simpson, Jared, Stern, Seth, Strug, Lisa, Taher, Ahmed, Greenfeld, Elena, Bombard, Yvonne, Noor, Abdul, Faghfoury, Hanna, Taher, Jennifer, Lerner-Ellis, Jordan

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P574: Summary of findings from comprehensive genome sequencing performed in a healthy population cohort by Casalino, Selina, Mahajan, Radhika, Aujla, Navneet, Frangione, Erika, Jayachandran, Lochana, Arnoldo, Saranya, Bearss, Erin, Binnie, Alexandra, Borgundvaag, Bjug, Chertkow, Howard, Chowdhary, Sunakshi, Clausen, Marc, Dagher, Marc, Devine, Luke, Dickson, Brendan, Di Iorio, David, Jordan Fung, Chun Yiu, Friedman, Steven, Gingras, Anne-Claude, Goneau, Lee, Haller, Simona, Hao, Limin, Kaushik, Deepanjali, Khan, Zeeshan, Lane, William, Lapadula, Elisa, Lebo, Matthew, Lu, Tiffany, MacDonald, Georgia, Mazzulli, Tony, McGeer, Allison, McLeod, Shelley, Mighton, Chloe, Morgan, Gregory, Nomigolzar, Romina, Pugh, Trevor, Richardson, David, Scott, Mackenzie, Simpson, Jared, Stern, Seth, Strug, Lisa, Taher, Ahmed, Thakur, Shilpa, Wolday, Dawit, Wong, Iris, Young, Juliet, Zarei, Natasha, Greenfeld, Elena, Bombard, Yvonne, Noor, Abdul, Faghfoury, Hanna, Taher, Jennifer, Lerner-Ellis, Jordan

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Central nervous system regulation of hepatic lipid and lipoprotein metabolism by Taher, Jennifer, Farr, Sarah, Adeli, Khosrow

“…Hepatic lipid and lipoprotein metabolism is an important determinant of fasting dyslipidemia and the development of fatty liver disease. Although endocrine…”
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Preparing for another Ebola Outbreak: The impact of viral inactivation methods on commonly measured biochemistry analytes in plasma and urine by Zhou, Janet, Sevilleno, Franceska, Rokhforooz, Fari, Taher, Jennifer

“…•Triton X-100 did not interfere with electrolytes, enzymes, and proteins in plasma.•Heat exposure negatively impacted assessment of enzymes in plasma.•Triton…”
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Central nervous system regulation of intestinal lipid and lipoprotein metabolism by Farr, Sarah, Taher, Jennifer, Adeli, Khosrow

“…In response to nutrient availability, the small intestine and brain closely communicate to modulate energy homeostasis and metabolism. The gut-brain axis…”
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MicroRNAs and Noncoding RNAs in Hepatic Lipid and Lipoprotein Metabolism: Potential Therapeutic Targets of Metabolic Disorders by Sud, Neetu, Taher, Jennifer, Su, Qiaozhu

“…ABSTRACT Preclinical Research Noncoding RNAs and microRNAs (miRNAs) represent an important class of regulatory molecules that modulate gene expression. The…”
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Benefits and harms of wellness initiatives by Fiala, Clare, Taher, Jennifer, Diamandis, Eleftherios P

“…Wellness projects are large scale studies of healthy individuals through extensive laboratory and other testing. The "Hundred Person Wellness Study", was one…”
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Pediatric evaluation of clinical specificity and sensitivity of SARS-CoV-2 IgG and IgM serology assays by Bohn, Mary Kathryn, Hall, Alexandra, Wilson, Siobhan, Taher, Jennifer, Sepiashvili, Lusia, Adeli, Khosrow

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Applications of SARS-CoV-2 serological testing: impact of test performance, sample matrices, and patient characteristics by Fung, Chun Yiu Jordan, Scott, Mackenzie, Lerner-Ellis, Jordan, Taher, Jennifer

“…Laboratory testing has been a key tool in managing the SARS-CoV-2 global pandemic. While rapid antigen and PCR testing has proven useful for diagnosing acute…”
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Reference Interval Harmonization: Harnessing the Power of Big Data Analytics to Derive Common Reference Intervals across Populations and Testing Platforms by Bohn, Mary Kathryn, Bailey, Dana, Balion, Cynthia, Cembrowski, George, Collier, Christine, De Guire, Vincent, Higgins, Victoria, Jung, Benjamin, Ali, Zahraa Mohammed, Seccombe, David, Taher, Jennifer, Tsui, Albert K Y, Venner, Allison, Adeli, Khosrow

“…Abstract Background Harmonization in laboratory medicine is essential for consistent and accurate clinical decision-making. There is significant and…”
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Bias in IGF-1 concentrations and interpretation across three different clinical laboratory assays by Mohammed-Ali, Zahraa, Delaney, Sarah, Singh, Ravinder, Leung, Felix, Taher, Jennifer, Goguen, Jeannette, Gilmour, Julie, Sepiashvili, Lusia, Beriault, Daniel R.

“…•Falsely elevated IGF-1 values result in unnecessary and extensive follow-up testing to rule out acromegaly and gigantism.•The Roche IGF-1 assay shows better…”
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Validating thyroid-stimulating hormone (TSH) reflexive testing cutpoints in a tertiary care institution by Taher, Jennifer, Brinc, Davor, Gilmour, Julie A, Beriault, Daniel R

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