Search Results - "Tahara, Katsutoshi"

Pharmacokinetic Analysis of Transcellular Transport of Levofloxacin across LLC-PK1 and Caco-2 Cell Monolayers by Takaai, Mari, Suzuki, Hisaki, Ishida, Kazuya, Tahara, Katsutoshi, Hashimoto, Yukiya

“…To characterize the membrane transport responsible for the renal excretion and intestinal absorption of levo-floxacin, we performed pharmacokinetic analysis of…”
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Directional Transcellular Transport of Bisoprolol in P-glycoprotein-expressed LLC-GA5-COL150 Cells but not in Renal Epithelial LLC-PK1 Cells by Tahara, Katsutoshi, Kagawa, Yuka, Takaai, Mari, Taguchi, Masato, Hashimoto, Yukiya

“…To evaluate the mechanism responsible for the tubular secretion of bisoprolol, we compared transcellular transport of bisoprolol with that of…”
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Nonlinear Mixed Effects Model Analysis of the Pharmacokinetics of Metoprolol in Routinely Treated Japanese Patients by Taguchi, Masato, Nozawa, Takashi, Mizumaki, Kouichi, Inoue, Hiroshi, Tahara, Katsutoshi, Takesono, Chihiro, Hashimoto, Yukiya

“…This study was performed to estimate the mean pharmacokinetic parameters of routinely administered metoprolol in middle-aged and elderly Japanese patients…”
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The Apical Uptake Transporter of Levofloxacin is Distinct from the Peptide Transporter in Human Intestinal Epithelial Caco-2 Cells by Fukumori, Shiro, Murata, Toshiya, Takaai, Mari, Tahara, Katsutoshi, Taguchi, Masato, Hashimoto, Yukiya

“…The aim of this study was to investigate the involvement of the peptide transporter for absorption of levofloxacin in Caco-2 cells. To evaluate the activity of…”
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Pharmacokinetic Variability of Routinely Administered Bisoprolol in Middle-Aged and Elderly Japanese Patients by Taguchi, Masato, Nozawa, Takashi, Igawa, Akihiko, Inoue, Hiroshi, Takesono, Chihiro, Tahara, Katsutoshi, Hashimoto, Yukiya

“…The nonlinear mixed effects model (NONMEM) was used to analyze the pharmacokinetics of routinely administered bisoprolol in middle-aged and elderly Japanese…”
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Nonlinear Mixed Effects Model Analysis of the Pharmacokinetics of Routinely Administered Bepridil in Japanese Patients with Arrhythmias by Taguchi, Masato, Fujiki, Akira, Iwamoto, Jotaro, Inoue, Hiroshi, Tahara, Katsutoshi, Saigusa, Katsuya, Horiuchi, Isao, Oshima, Yukari, Hashimoto, Yukiya

“…This study was performed to evaluate variability in the pharmacokinetics of bepridil in 38 Japanese patients with arrhythmias, and to investigate the effects…”
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Pharmacokinetics and Pharmacodynamics of Bisoprolol in Rats with Bilateral Ureter Ligation-induced Renal Failure by Tahara, Katsutoshi, Saigusa, Katsuya, Kagawa, Yuka, Taguchi, Masato, Hashimoto, Yukiya

“…The effect of renal failure on the pharmacokinetics and pharmacodynamics of bisoprolol was investigated in bilateral ureter-ligated (BUL) rats. The blood…”
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CD40 is expressed in the subsets of endothelial cells undergoing partial endothelial–mesenchymal transition in tumor microenvironment by Takahashi, Kazuki, Kobayashi, Miho, Katsumata, Hisae, Tokizaki, Shiori, Anzai, Tatsuhiko, Ikeda, Yukinori, Alcaide, Daniel M., Maeda, Kentaro, Ishihara, Makoto, Tahara, Katsutoshi, Kubota, Yoshiaki, Itoh, Fumiko, Park, Jihwan, Takahashi, Kunihiko, Matsunaga, Yukiko T., Yoshimatsu, Yasuhiro, Podyma‐Inoue, Katarzyna A., Watabe, Tetsuro

“…Tumor progression and metastasis are regulated by endothelial cells undergoing endothelial–mesenchymal transition (EndoMT), a cellular differentiation process…”
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Directional Transcellular Transport of Bisoprolol in P-glycoprotein-expressed LLC-GA5-COL150 Cells, but not in Renal Epithelial LLC-PK1 Cells by Katsutoshi TAHARA, Yuka KAGAWA, Mari TAKAAI, Masato TAGUCHI, Yukiya HASHIMOTO

“…[Summary] To evaluate the mechanism responsible for the tubular secretion of bisoprolol, we compared transcellular transport of bisoprolol with that of…”
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Pharmacokinetics and Pharmacodynamics of Bisoprolol in Rats with Bilateral Ureter Ligation-induced Renal Failure by Katsutoshi TAHARA, Katsuya SAIGUSA, Yuka KAGAWA, Masato TAGUCHI, Yukiya HASHIMOTO

“…The effect of renal failure on the pharmacokinetics and pharmacodynamics of bisoprolol was investigated in bilateral ureter-ligated (BUL) rats. The blood…”
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Influence of CYP2D6 Genotype on Metoprolol Plasma Concentration and β-Adrenergic Inhibition During Long-Term Treatment: A Comparison With Bisoprolol by Nozawa, Takashi, Taguchi, Masato, Tahara, Katsutoshi, Hashimoto, Yukiya, Igarashi, Norio, Nonomura, Makoto, Kato, Bun-ichi, Igawa, Akihiko, Inoue, Hiroshi

“…In patients routinely treated with metoprolol, influences of CYP2D6 genotype on the response of heart rate to isoproterenol (IP) were studied at its peak and…”
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