Search Results - "Taha, Ameer Y"
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Early detection of lipid oxidation in infant milk formula by measuring free oxylipins—Comparison with hydroperoxide value and thiobarbituric acid reactive substance methods
Published in Journal of food science (01-12-2022)“…Infant milk formula was used as a model food to compare the sensitivity of thiobarbituric acid reactive substances (TBARS) and hydroperoxide methods to…”
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Oxidized linoleic acid metabolites induce liver mitochondrial dysfunction, apoptosis, and NLRP3 activation in mice
Published in Journal of lipid research (01-09-2018)“…Circulating oxidized linoleic acid (LA) metabolites (OXLAMs) are increased in patients with nonalcoholic steatohepatitis (NASH) and their levels correlate with…”
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Brain oxylipin concentrations following hypercapnia/ischemia: effects of brain dissection and dissection time[S]
Published in Journal of lipid research (01-03-2019)“…PUFAs are precursors to bioactive oxylipin metabolites that increase in the brain following CO2-induced hypercapnia/ischemia. It is not known whether the…”
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Serum metabolomic biomarkers of perceptual speed in cognitively normal and mildly impaired subjects with fasting state stratification
Published in Scientific reports (23-09-2021)“…Cognitive decline is associated with both normal aging and early pathologies leading to dementia. Here we used quantitative profiling of metabolites involved…”
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Altered fatty acid concentrations in prefrontal cortex of schizophrenic patients
Published in Journal of psychiatric research (01-05-2013)“…Abstract Background Disturbances in prefrontal cortex phospholipid and fatty acid composition have been reported in patients with schizophrenia (SCZ), often as…”
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Cytochrome P450-soluble epoxide hydrolase derived linoleic acid oxylipins and cognitive performance in type 2 diabetes
Published in Journal of lipid research (01-07-2023)“…Type 2 diabetes mellitus (T2DM) increases the risk of cognitive decline and dementia. Disruptions in the cytochrome P450-soluble epoxide hydrolase (CYP450-sEH)…”
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Dietary Linoleic Acid Lowering Reduces Lipopolysaccharide-Induced Increase in Brain Arachidonic Acid Metabolism
Published in Molecular neurobiology (01-08-2017)“…Linoleic acid (LA, 18:2n-6) is a precursor to arachidonic acid (AA, 20:4n-6), which can be converted by brain lipoxygenase and cyclooxygenase (COX) enzymes…”
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Linoleic acid participates in the response to ischemic brain injury through oxidized metabolites that regulate neurotransmission
Published in Scientific reports (28-06-2017)“…Linoleic acid (LA; 18:2 n-6), the most abundant polyunsaturated fatty acid in the US diet, is a precursor to oxidized metabolites that have unknown roles in…”
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Effects of diets enriched in linoleic acid and its peroxidation products on brain fatty acids, oxylipins, and aldehydes in mice
Published in Biochimica et biophysica acta. Molecular and cell biology of lipids (01-10-2018)“…Linoleic acid (LA) is abundant in modern industrialized diets. Oxidized LA metabolites (OXLAMs) and reactive aldehydes, such as 4-hydroxy-2-nonenal (4-HNE),…”
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Validation of a One‐Step Method for Extracting Fatty Acids from Salmon, Chicken and Beef Samples
Published in Journal of food science (01-10-2017)“…Fatty acid extraction methods are time‐consuming and expensive because they involve multiple steps and copious amounts of extraction solvents. In an effort to…”
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Multi-omic brain and behavioral correlates of cell-free fetal DNA methylation in macaque maternal obesity models
Published in Nature communications (21-09-2022)“…Maternal obesity during pregnancy is associated with neurodevelopmental disorder (NDD) risk. We utilized integrative multi-omics to examine maternal obesity…”
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Dietary resistant starch supplementation increases gut luminal deoxycholic acid abundance in mice
Published in Gut microbes (2024)“…Bile acids (BA) are among the most abundant metabolites produced by the gut microbiome. Primary BAs produced in the liver are converted by gut bacterial…”
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Soluble Epoxide Hydrolase Derived Linoleic Acid Oxylipins, Small Vessel Disease Markers, and Neurodegeneration in Stroke
Published in Journal of the American Heart Association (03-01-2023)“…Background Cerebral small vessel disease is associated with higher ratios of soluble-epoxide hydrolase derived linoleic acid diols (12,13-dihydroxyoctadecenoic…”
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14
Triacylglycerols are preferentially oxidized over free fatty acids in heated soybean oil
Published in NPJ science of food (01-04-2021)“…In oil, free fatty acids (FFAs) are thought to be the preferred substrate for lipid oxidation although triacylglycerols (TAGs) are the predominant lipid class…”
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Disturbed brain phospholipid and docosahexaenoic acid metabolism in calcium-independent phospholipase A2-VIA (iPLA2β)-knockout mice
Published in Biochimica et biophysica acta. Molecular and cell biology of lipids (01-09-2012)“…Calcium-independent phospholipase A2 group VIA (iPLA2β) releases docosahexaenoic acid (DHA) from phospholipids in vitro. Mutations in the iPLA2β gene, PLA2G6,…”
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Bioconversion of cheese whey permeate into fungal oil by Mucor circinelloides
Published in Journal of biological engineering (14-11-2018)“…Oleaginous fungi are efficient tools to convert agricultural waste streams into valuable components. The filamentous fungus was cultivated in whey permeate, a…”
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Assessing Repeated Urinary Proline Betaine Measures as a Biomarker of Usual Citrus Intake during Pregnancy: Sources of Within-Person Variation and Correlation with Reported Intake
Published in Metabolites (01-08-2023)“…Proline betaine (Pro-B) has been identified as a biomarker of dietary citrus intake, yet gaps remain in its validation as a quantitative predictor of intake…”
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Glycoproteomic and Lipidomic Characterization of Industrially Produced Whey Protein Phospholipid Concentrate with Emphasis on Antimicrobial Xanthine Oxidase, Oxylipins and Small Milk Fat Globules
Published in Dairy (Basel) (01-06-2022)“…This work investigates the composition of whey protein phospholipid concentrate (WPPC), an underutilized dairy stream, and reveals that it is a source of many…”
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Design and fabrication of a highly sensitive and naked-eye distinguishable colorimetric biosensor for chloramphenicol detection by using ELISA on nanofibrous membranes
Published in Talanta (Oxford) (01-09-2020)“…Enzyme-linked immunoassay (ELISA) is highly specific and selective towards target molecules and is convenient for on-site detection. However, in many cases,…”
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Impact of Maternal Obesity on the Gestational Metabolome and Infant Metabolome, Brain, and Behavioral Development in Rhesus Macaques
Published in Metabolites (01-08-2022)“…Maternal gestational obesity is associated with elevated risks for neurodevelopmental disorder, including autism spectrum disorder. However, the mechanisms by…”
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