Search Results - "Tadayon, Roya"
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Structural basis of the specificity of USP18 toward ISG15
Published in Nature structural & molecular biology (01-03-2017)“…The specificity of USP18's deconjugating activity toward ISG15, a ubiquitin-like protein induced by interferon, is revealed by structural and biochemistry…”
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A mechanistic review of Parkin activation
Published in Biochimica et biophysica acta. General subjects (01-06-2021)“…Parkin and phosphatase and tensin homolog (PTEN)-induced kinase 1 (PINK1) constitute a feed-forward signalling pathway that mediates autophagic removal of…”
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Calcium binds and rigidifies the dysferlin C2A domain in a tightly coupled manner
Published in Biochemical journal (15-01-2021)“…The membrane protein dysferlin (DYSF) is important for calcium-activated plasma membrane repair, especially in muscle fibre cells. Nearly 600 mutations in the…”
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Capturing the catalytic intermediates of parkin ubiquitination
Published in Proceedings of the National Academy of Sciences - PNAS (06-08-2024)“…Parkin is an E3 ubiquitin ligase implicated in early-onset forms of Parkinson's disease. It catalyzes a transthiolation reaction by accepting ubiquitin (Ub)…”
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Distinct phosphorylation signals drive acceptor versus free ubiquitin chain targeting by parkin
Published in Biochemical journal (31-03-2022)“…The RBR E3 ligase parkin is recruited to the outer mitochondrial membrane (OMM) during oxidative stress where it becomes activated and ubiquitinates numerous…”
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Characterization of RAGE-ligand interactions
Published in Acta crystallographica. Section A, Foundations and advances (28-08-2016)“…Abstract only…”
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Fluoxetine competes with cortisol for binding to human serum albumin
Published in Iranian journal of pharmaceutical research : IJPR (01-01-2012)“…Human serum albumin (HSA) is an important protein that carries variety of substances like some hormones and drugs in blood. Pharmacological studies of the…”
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Glucose and fluoxetine induce fine structural change in human serum albumin
Published in Iranian journal of pharmaceutical research : IJPR (2013)“…Human serum albumin has been used as a model protein for protein folding and ligand binding studies over many decades. Due to its long life period and high…”
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