Search Results - "Tachibana, Ayumi"
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Behavioral and psychological symptoms and brain volumes in community-dwelling older persons from the Nakayama Study
Published in Scientific reports (30-10-2024)“…The frequency of behavioral and psychological symptoms of dementia (BPSD) is high, and it is a challenge to elucidate its neural substrates underlying their…”
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Metabolomic alterations in the blood plasma of older adults with mild cognitive impairment and Alzheimer’s disease (from the Nakayama Study)
Published in Scientific reports (08-09-2022)“…Alzheimer's disease (AD) is a progressive disease, and the number of AD patients is increasing every year as the population ages. One of the pathophysiological…”
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Effects of AGXT2 variants on blood pressure and blood sugar among 750 older Japanese subjects recruited by the complete enumeration survey method
Published in BMC genomics (20-04-2021)“…Alanine:glyoxylate aminotransferase 2 (AGXT2; EC 2.6.1.44) is the only enzyme that degrades the R-form of 3-aminoisobutyrate, an intermediate metabolite of…”
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Serum high-sensitivity C-reactive protein and dementia in a community-dwelling Japanese older population (JPSC-AD)
Published in Scientific reports (28-03-2024)“…In recent years, the association between neuroinflammatory markers and dementia, especially Alzheimer’s disease (AD), has attracted much attention. However,…”
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Secular trends in the prevalence of dementia based on a community‐based complete enumeration in Japan: the Nakayama Study
Published in Psychogeriatrics (01-09-2022)“…Background The number of dementia patients is increasing worldwide, especially in Japan, which has the world's highest ageing population. The increase in the…”
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Late-Life High Blood Pressure and Enlarged Perivascular Spaces in the Putaminal Regions of Community-Dwelling Japanese Older Persons
Published in Journal of geriatric psychiatry and neurology (01-01-2024)“…Background Enlarged perivascular spaces (EPVS) of the brain may be involved in dementia, such as Alzheimer’s disease and cerebral small vessel disease (CSVD)…”
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Association Between Frequency of Social Contact and Brain Atrophy in Community-Dwelling Older People Without Dementia: The JPSC-AD Study
Published in Neurology (12-09-2023)“…Epidemiological evidence has shown that social isolation, a low frequency of social contact with others, is associated with the risk of dementia and late-life…”
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Study design and baseline characteristics of a population-based prospective cohort study of dementia in Japan: the Japan Prospective Studies Collaboration for Aging and Dementia (JPSC-AD)
Published in Environmental health and preventive medicine (31-10-2020)“…Background The burden of dementia is growing rapidly and has become a medical and social problem in Japan. Prospective cohort studies have been considered an…”
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Altruistic Social Activity, Depressive Symptoms, and Brain Regional Gray Matter Volume: Voxel-Based Morphometry Analysis From 8,695 Old Adults
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (01-09-2022)“…Abstract Altruistic social activity, such as giving support to others, has shown protective benefits on dementia risk and cognitive decline. However, the…”
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Analysis of factors related to cognitive impairment in a community‐based, complete enumeration survey in Japan: the Nakayama study
Published in Psychogeriatrics (01-09-2023)“…Background The number of patients with cognitive disorders is rapidly increasing in the world, becoming not only a medical problem, but also a social problem…”
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Glucose metabolism and smaller hippocampal volume in elderly people with normal cognitive function
Published in npj aging (09-09-2024)“…We investigated associations of glycemic measures, and insulin resistance and secretion measures with hippocampal and subfield volumes. In this cross-sectional…”
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CKD, Brain Atrophy, and White Matter Lesion Volume: The Japan Prospective Studies Collaboration for Aging and Dementia
Published in Kidney medicine (01-03-2023)“…Chronic kidney disease, defined by albuminuria and/or reduced estimated glomerular filtration rate (eGFR), has been reported to be associated with brain…”
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CKD, Brain Atrophy, and White Matter Lesion Volume: The Japan Prospective Studies Collaboration for Aging and DementiaPlain-Language summary
Published in Kidney medicine (01-03-2023)“…Rationale & Objective: Chronic kidney disease, defined by albuminuria and/or reduced estimated glomerular filtration rate (eGFR), has been reported to be…”
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