Search Results - "Tabernero, María Dolores"

Clinical, Histopathologic and Genetic Features of Rhabdoid Meningiomas by Garrido Ruiz, Patricia Alejandra, González-Tablas, María, Pasco Peña, Alejandro, Zelaya Huerta, María Victoria, Ortiz, Javier, Otero, Álvaro, Corchete, Luis Antonio, Ludeña, María Dolores, Caballero Martínez, María Cristina, Córdoba Iturriagagoitia, Alicia, Fernández, Inmaculada Catalina, González-Carreró Fojón, Joaquín, Hernández Laín, Aurelio, Orfao, Alberto, Tabernero, María Dolores

“…Rhabdoid meningiomas (RM) shows heterogeneous histological findings, and a wide variety of chromosomal copy number alterations (CNA) are associated with an…”
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Multivariate analysis reveals differentially expressed genes among distinct subtypes of diffuse astrocytic gliomas: diagnostic implications by González-García, Nerea, Nieto-Librero, Ana Belén, Vital, Ana Luisa, Tao, Herminio José, González-Tablas, María, Otero, Álvaro, Galindo-Villardón, Purificación, Orfao, Alberto, Tabernero, María Dolores

“…Diagnosis and classification of gliomas mostly relies on histopathology and a few genetic markers. Here we interrogated microarray gene expression profiles…”
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Whole-Exome Sequencing Reveals Recurrent but Heterogeneous Mutational Profiles in Sporadic WHO Grade 1 Meningiomas by González-Tablas, María, Prieto, Carlos, Arandia, Daniel, Jara-Acevedo, María, Otero, Álvaro, Pascual, Daniel, Ruíz, Laura, Álvarez-Twose, Iván, García-Montero, Andrés Celestino, Orfao, Alberto, Tabernero, María Dolores

“…Human WHO grade 1 meningiomas are generally considered benign tumors; despite this, they account for ≈50% of all recurrent meningiomas. Currently, limited data…”
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Paired Primary and Recurrent Rhabdoid Meningiomas: Cytogenetic Alterations, BAP1 Gene Expression Profile and Patient Outcome by Garrido Ruiz, Patricia Alejandra, Rodriguez, Álvaro Otero, Corchete, Luis Antonio, Zelaya Huerta, Victoria, Pasco Peña, Alejandro, Caballero Martínez, Cristina, González-Carreró Fojón, Joaquín, Catalina Fernández, Inmaculada, López Duque, Juan Carlos, Zaldumbide Dueñas, Laura, Mosteiro González, Lorena, Astudillo, María Aurora, Hernández-Laín, Aurelio, Camacho Urkaray, Emma Natalia, Viguri Diaz, María Amparo, Orfao, Alberto, Tabernero, María Dolores

“…Rhabdoid meningiomas (RM) are a rare meningioma subtype with a heterogeneous clinical course which is more frequently associated with recurrence, even among…”
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Amplified and homozygously deleted genes in glioblastoma: impact on gene expression levels by Crespo, Inês, Tão, Hermínio, Nieto, Ana Belen, Rebelo, Olinda, Domingues, Patrícia, Vital, Ana Luísa, Patino, Maria del Carmen, Barbosa, Marcos, Lopes, Maria Celeste, Oliveira, Catarina Resende, Orfao, Alberto, Tabernero, María Dolores

“…Glioblastoma multiforme (GBM) displays multiple amplicons and homozygous deletions that involve relevant pathogenic genes and other genes whose role remains…”
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Early recurrences in histologically benign/grade I meningiomas are associated with large tumors and coexistence of monosomy 14 and del(1p36) in the ancestral tumor cell clone by Maillo, Angel, Orfao, Alberto, Espinosa, Ana B, Sayagués, José María, Merino, Marta, Sousa, Pablo, Lara, Monica, Tabernero, María Dolores

“…Tumor recurrence is the major clinical complication in meningiomas, and its prediction in histologically benign/grade I tumors remains a challenge. In this…”
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Tumor infiltrating immune cells in gliomas and meningiomas by Domingues, Patrícia, González-Tablas, María, Otero, Álvaro, Pascual, Daniel, Miranda, David, Ruiz, Laura, Sousa, Pablo, Ciudad, Juana, Gonçalves, Jesús María, Lopes, María Celeste, Orfao, Alberto, Tabernero, María Dolores

“…Highlights • The presence of tumor infiltrates by immune cells has been reported in both gliomas and meningiomas. • Tumor-infiltrating immune cells play a very…”
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The Cytogenetic Relationship between Primary and Recurrent Meningiomas Points to the Need for New Treatment Strategies in Cases at High Risk of Relapse by ESPINOSA, Ana Belén, TABERNERO, Maria Dolores, ORFAO, Alberto, MAILLO, Angel, SAYAGUES, José Maria, CIUDAD, Juana, MERINO, Marta, ALGUERO, Maria Carmen, LUBOMBO, Anne Marie, SOUSA, Pablo, SANTOS-BRIZ, Angel

“…Purpose: Recurrence is the major factor influencing the clinical outcome of meningioma patients although the exact relationship between primary and recurrent…”
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Molecular and Genomic Alterations in Glioblastoma Multiforme by Crespo, Ines, Vital, Ana Louisa, Gonzalez-Tablas, María, Patino, María del Carmen, Otero, Alvaro, Lopes, María Celeste, de Oliveira, Catarina, Domingues, Patricia, Orfao, Alberto, Tabernero, Maria Dolores

“…In recent years, important advances have been achieved in the understanding of the molecular biology of glioblastoma multiforme (GBM); thus, complex genetic…”
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Patient Gender Is Associated with Distinct Patterns of Chromosomal Abnormalities and Sex Chromosome–Linked Gene‐Expression Profiles in Meningiomas by Tabernero, María Dolores, Espinosa, Ana Belén, Maillo, Angel, Rebelo, Olinda, Vera, Jaime Fernandez, Sayagues, José María, Merino, Marta, Diaz, Pedro, Sousa, Pablo, Orfao, Alberto

“…The female predominance of meningiomas has been established, but how this is affected by hormones is still under discussion. We analyzed the characteristics of…”
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Tumor cell and immune cell profiles in primary human glioblastoma: Impact on patient outcome by González‐Tablas Pimenta, María, Otero, Álvaro, Arandia Guzman, Daniel Angel, Pascual‐Argente, Daniel, Ruíz Martín, Laura, Sousa‐Casasnovas, Pablo, García‐Martin, Andoni, Roa Montes de Oca, Juan Carlos, Villaseñor‐Ledezma, Javier, Torres Carretero, Luis, Almeida, Maria, Ortiz, Javie, Nieto, Adelaida, Orfao, Alberto, Tabernero, María Dolores

“…The distribution and role of tumor‐infiltrating leucocytes in glioblastoma (GBM) remain largely unknown. Here, we investigated the cellular composition of 55…”
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New Classification Scheme for the Prognostic Stratification of Meningioma on the Basis of Chromosome 14 Abnormalities, Patient Age, and Tumor Histopathology by Maillo, Angel, Orfao, Alberto, Sayagues, José María, Diaz, Pedro, Gómez-Moreta, Juan Antonio, Caballero, Marcelino, Santamarta, David, Santos-Briz, Angel, Morales, Francisco, Tabernero, María Dolores

“…Meningiomas are usually considered benign tumors. However, relapses occur in 10% to 20% of all patients, including both histopathologically aggressive and…”
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Array-based comparative genomic hybridization of mapped BAC DNA clones to screen for chromosome 14 copy number abnormalities in meningiomas by ESPINOSA, Ana Belén, MACKINTOSH, Carlos, MAILLO, Angel, GUTIERREZ, Laura, SOUSA, Pablo, MERINO, Marta, ORTIZ, Javier, DE ALAVA, Enrique, ORFAO, Alberto, TABERNERO, Maria Dolores

“…Chromosome 14 loss in meningiomas are associated with more aggressive tumour behaviour. To date, no studies have been reported in which the entire chromosome…”
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Proposal for a new risk stratification classification for meningioma based on patient age, WHO tumor grade, size, localization, and karyotype by Domingues, Patrícia Henriques, Sousa, Pablo, Otero, Álvaro, Gonçalves, Jesus Maria, Ruiz, Laura, de Oliveira, Catarina, Lopes, Maria Celeste, Orfao, Alberto, Tabernero, Maria Dolores

“…Tumor recurrence remains the major clinical complication of meningiomas, the majority of recurrences occurring among WHO grade I/benign tumors. In the present…”
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Genetic/molecular alterations of meningiomas and the signaling pathways targeted by Domingues, Patrícia, González-Tablas, María, Otero, Álvaro, Pascual, Daniel, Ruiz, Laura, Miranda, David, Sousa, Pablo, Gonçalves, Jesús María, Lopes, María Celeste, Orfao, Alberto, Tabernero, María Dolores

“…Meningiomas are usually considered to be benign central nervous system tumors; however, they show heterogenous clinical, histolopathological and cytogenetic…”
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The importance of considering competing risks in recurrence analysis of intracranial meningioma by Mirian, Christian, Jensen, Lasse Rehné, Juratli, Tareq A., Maier, Andrea Daniela, Torp, Sverre H., Shih, Helen A., Morshed, Ramin A., Young, Jacob S., Magill, Stephen T., Bertero, Luca, Stummer, Walter, Spille, Dorothee Cäcilia, Brokinkel, Benjamin, Oya, Soichi, Miyawaki, Satoru, Saito, Nobuhito, Proescholdt, Martin, Kuroi, Yasuhiro, Gousias, Konstantinos, Simon, Matthias, Moliterno, Jennifer, Prat-Acin, Ricardo, Goutagny, Stéphane, Prabhu, Vikram C., Tsiang, John T., Wach, Johannes, Güresir, Erdem, Yamamoto, Junkoh, Kim, Young Zoon, Lee, Joo Ho, Koshy, Matthew, Perumal, Karthikeyan, Baskaya, Mustafa K., Cannon, Donald M., Shrieve, Dennis C., Suh, Chang-Ok, Chang, Jong Hee, Kamenova, Maria, Straumann, Sven, Soleman, Jehuda, Eyüpoglu, Ilker Y., Catalan, Tony, Lui, Austin, Theodosopoulos, Philip V., McDermott, Michael W., Wang, Fang, Guo, Fuyou, Góes, Pedro, de Paiva Neto, Manoel Antonio, Jamshidi, Aria, Komotar, Ricardo, Ivan, Michael, Luther, Evan, Souhami, Luis, Guiot, Marie-Christine, Csonka, Tamás, Endo, Toshiki, Barrett, Olivia Claire, Jensen, Randy, Gupta, Tejpal, Patel, Akash J., Klisch, Tiemo J., Kim, Jun Won, Maiuri, Francesco, Barresi, Valeria, Tabernero, María Dolores, Skyrman, Simon, Broechner, Anders, Bach, Mathias Jacobsen, Law, Ian, Scheie, David, Kristensen, Bjarne Winther, Munch, Tina Nørgaard, Meling, Torstein, Fugleholm, Kåre, Blanche, Paul, Mathiesen, Tiit

“…Background The risk of recurrence is overestimated by the Kaplan–Meier method when competing events, such as death without recurrence, are present. Such…”
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Fluorescence in situ hybridization analysis of aneuploidization patterns in monoclonal gammopathy of undetermined significance versus multiple myeloma and plasma cell leukemia by Ana, Rasillo, Dolores, Tabernero María, Luz, Sánchez María, de Andrés Martín, Pérez, Marta, Martín Ayuso, José, Hernández, Jesús, Moro María, Javier, Fernández‐Calvo, María, Sayagués José, Aglae, Bortoluci, Fernando, San Miguel Jesús, Alberto, Orfao

“…BACKGROUND Monoclonal gammopathy of undetermined significance (MGUS) is a clonal plasma cell (PC) disorder usually characterized by a benign clinical course…”
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Heterogeneous EGFR , CDK4 , MDM4 , and PDGFRA Gene Expression Profiles in Primary GBM: No Association with Patient Survival by González-Tablas, María, Arandia, Daniel, Jara-Acevedo, María, Otero, Álvaro, Vital, Ana-Luisa, Prieto, Carlos, González-Garcia, Nerea, Nieto-Librero, Ana Belén, Tao, Herminio, Pascual, Daniel, Ruiz, Laura, Sousa, Pablo, Galindo-Villardón, Purificación, Orfao, Alberto, Tabernero, María Dolores

“…The prognostic impact of the expression profile of genes recurrently amplified in glioblastoma multiforme (GBM) remains controversial. We investigated the RNA…”
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Association between inflammatory infiltrates and isolated monosomy 22/del(22q) in meningiomas by Domingues, Patrícia Henriques, Teodósio, Cristina, Otero, Álvaro, Sousa, Pablo, Ortiz, Javier, Macias, María del Carmen García, Gonçalves, Jesús María, Nieto, Ana Belén, Lopes, María Celeste, de Oliveira, Catarina, Orfao, Alberto, Tabernero, Maria Dolores

“…Meningiomas contain highly variable levels of infiltrating tissue macrophages (TiMa) and other immune cells. In this study we investigated the potential…”
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Phenotypic profile of expanded NK cells in chronic lymphoproliferative disorders: a surrogate marker for NK-cell clonality by Bárcena, Paloma, Jara-Acevedo, María, Tabernero, María Dolores, López, Antonio, Sánchez, María Luz, García-Montero, Andrés C, Muñoz-García, Noemí, Vidriales, María Belén, Paiva, Artur, Lecrevisse, Quentin, Lima, Margarida, Langerak, Anton W, Böttcher, Sebastian, van Dongen, Jacques J M, Orfao, Alberto, Almeida, Julia

“…Currently, the lack of a universal and specific marker of clonality hampers the diagnosis and classification of chronic expansions of natural killer (NK)…”
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