Search Results - "Tabb, David L"
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Skyline: an open source document editor for creating and analyzing targeted proteomics experiments
Published in Bioinformatics (01-04-2010)“…Skyline is a Windows client application for targeted proteomics method creation and quantitative data analysis. It is open source and freely available for…”
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Employing ProteoWizard to Convert Raw Mass Spectrometry Data
Published in Current protocols in bioinformatics (17-06-2014)“…After raw data have been captured by mass spectrometers in biological LC-MS/MS experiments, they must be converted from vendor-specific binary files to…”
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The Evolutionary Imprint of Domestication on Genome Variation and Function of the Filamentous Fungus Aspergillus oryzae
Published in Current biology (07-08-2012)“…The domestication of animals, plants, and microbes fundamentally transformed the lifestyle and demography of the human species [1]. Although the genetic and…”
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Recognizing millions of consistently unidentified spectra across hundreds of shotgun proteomics datasets
Published in Nature methods (01-08-2016)“…A newly developed algorithm enabled clustering of all 256 million (66 million identified and 190 million unidentified) peptide MS/MS spectra available in the…”
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MyriMatch: Highly Accurate Tandem Mass Spectral Peptide Identification by Multivariate Hypergeometric Analysis
Published in Journal of proteome research (01-02-2007)“…Shotgun proteomics experiments are dependent upon database search engines to identify peptides from tandem mass spectra. Many of these algorithms score…”
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MetaNovo: An open-source pipeline for probabilistic peptide discovery in complex metaproteomic datasets
Published in PLoS computational biology (01-06-2023)“…Microbiome research is providing important new insights into the metabolic interactions of complex microbial ecosystems involved in fields as diverse as the…”
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A Face in the Crowd: Recognizing Peptides Through Database Search
Published in Molecular & cellular proteomics (01-11-2011)“…Peptide identification via tandem mass spectrometry sequence database searching is a key method in the array of tools available to the proteomics researcher…”
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Proteomic Parsimony through Bipartite Graph Analysis Improves Accuracy and Transparency
Published in Journal of proteome research (01-09-2007)“…Assembling peptides identified from LC−MS/MS spectra into a list of proteins is a critical step in analyzing shotgun proteomics data. As one peptide sequence…”
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Proteomics Standards Initiative: Fifteen Years of Progress and Future Work
Published in Journal of proteome research (01-12-2017)“…The Proteomics Standards Initiative (PSI) of the Human Proteome Organization (HUPO) has now been developing and promoting open community standards and software…”
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Proteomics Standards Initiative at Twenty Years: Current Activities and Future Work
Published in Journal of proteome research (03-02-2023)“…The Human Proteome Organization (HUPO) Proteomics Standards Initiative (PSI) has been successfully developing guidelines, data formats, and controlled…”
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Comparative Proteomics Analysis between Maize and Sorghum Uncovers Important Proteins and Metabolic Pathways Mediating Drought Tolerance
Published in Life (Basel, Switzerland) (01-01-2023)“…Drought severely affects crop yield and yield stability. Maize and sorghum are major crops in Africa and globally, and both are negatively impacted by drought…”
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Protein Identification Using Customized Protein Sequence Databases Derived from RNA-Seq Data
Published in Journal of proteome research (03-02-2012)“…The standard shotgun proteomics data analysis strategy relies on searching MS/MS spectra against a context-independent protein sequence database derived from…”
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SWATH-MS based proteomic profiling of pancreatic ductal adenocarcinoma tumours reveals the interplay between the extracellular matrix and related intracellular pathways
Published in PloS one (13-10-2020)“…Pancreatic cancer accounts for 2.8% of new cancer cases worldwide and is projected to become the second leading cause of cancer-related deaths by 2030…”
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The Human Proteome Organization–Proteomics Standards Initiative Quality Control Working Group: Making Quality Control More Accessible for Biological Mass Spectrometry
Published in Analytical chemistry (Washington) (18-04-2017)“…To have confidence in results acquired during biological mass spectrometry experiments, a systematic approach to quality control is of vital importance…”
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enterocyte microvillus is a vesicle-generating organelle
Published in The Journal of cell biology (29-06-2009)“…For decades, enterocyte brush border microvilli have been viewed as passive cytoskeletal scaffolds that serve to increase apical membrane surface area…”
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Proteomic Analysis of Chinese Hamster Ovary Cells
Published in Journal of proteome research (02-11-2012)“…To complement the recent genomic sequencing of Chinese hamster ovary (CHO) cells, proteomic analysis was performed on CHO cells including the cellular…”
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Greazy: Open-Source Software for Automated Phospholipid Tandem Mass Spectrometry Identification
Published in Analytical chemistry (Washington) (07-06-2016)“…Lipid identification from data produced with high-throughput technologies is essential to the elucidation of the roles played by lipids in cellular function…”
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DTASelect and Contrast: tools for assembling and comparing protein identifications from shotgun proteomics
Published in Journal of proteome research (01-01-2002)“…The components of complex peptide mixtures can be separated by liquid chromatography, fragmented by tandem mass spectrometry, and identified by the SEQUEST…”
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Advanced Proteogenomic Analysis Reveals Multiple Peptide Mutations and Complex Immunoglobulin Peptides in Colon Cancer
Published in Journal of proteome research (04-09-2015)“…Aiming toward an improved understanding of the regulation of proteins in cancer, recent studies from the Clinical Proteomic Tumor Analysis Consortium (CPTAC)…”
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proBAMsuite, a Bioinformatics Framework for Genome-Based Representation and Analysis of Proteomics Data
Published in Molecular & cellular proteomics (01-03-2016)“…To facilitate genome-based representation and analysis of proteomics data, we developed a new bioinformatics framework, proBAMsuite, in which a central…”
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