Search Results - "Tabas, L"

Selectivity of the multidrug resistance modulator, LY335979, for P-glycoprotein and effect on cytochrome P-450 activities by Dantzig, A H, Shepard, R L, Law, K L, Tabas, L, Pratt, S, Gillespie, J S, Binkley, S N, Kuhfeld, M T, Starling, J J, Wrighton, S A

“…Overexpression of ATP-dependent drug efflux pumps, P-glycoprotein (Pgp) or multidrug resistance-associated protein (MRP), confers multidrug resistance to tumor…”
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Association of Intestinal Peptide Transport with a Protein Related to the Cadherin Superfamily by Dantzig, Anne H., Hoskins, JoAnn, Tabas, Linda B., Bright, Stuart, Shepard, Robert L., Jenkins, Ivan L., Duckworth, Dale C., Sportsman, J. Richard, Mackensen, Daniel, Rosteck, Paul R., Skatrud, Paul L.

“…The first step in oral absorption of many medically important peptide-based drugs is mediated by an intestinal proton-dependent peptide transporter. This…”
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Structure-activity relationship of carbacephalosporins and cephalosporins: antibacterial activity and interaction with the intestinal proton-dependent dipeptide transport carrier of Caco-2 cells by SNYDER, N. J, TABAS, L. B, BERRY, D. M, DUCKWORTH, D. C, SPRY, D. O, DANTZIG, A. H

“…Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon…”
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Transport mechanisms responsible for the absorption of loracarbef, cefixime, and cefuroxime axetil into human intestinal Caco-2 cells by Dantzig, A H, Duckworth, D C, Tabas, L B

“…Loracarbef, cefixime and cefuroxime axetil are beta-lactam antibiotics that are administered orally. Oral absorption of loracarbef is nearly complete, while…”
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Reversal of resistance in multidrug resistance protein (MRP1)-overexpressing cells by LY329146 by Norman, Bryan H., Dantzig, Anne H., Kroin, Julian S., Law, Kevin L., Tabas, Linda B., Shepard, Robert L., Palkowitz, Alan D., Hauser, Kenneth L., Winter, Mark A., Sluka, James P., Starling, James J.

“…The benzothiophene LY329146 reverses the drug resistance phenotype in multidrug resistance protein (MRP1)-overexpressing cells when dosed in combination with…”
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Cefaclor uptake by the proton-dependent dipeptide transport carrier of human intestinal Caco-2 cells and comparison to cephalexin uptake by Dantzig, A H, Tabas, L B, Bergin, L

“…The human Caco-2 cell line spontaneously differentiates in culture to epithelial cells possessing intestinal enterocytic-like properties. These cells possess a…”
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Bridging the "Front Stage" and "Back Stage" in Service System Design by Glushko, R.J., Tabas, L.

“…Service management and design has thus far primarily focused on the interactions between employees and customers. This perspective holds that the quality of…”
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Regional transportation operations collaboration and coordination demonstration initiative by Guttridge, K., Koehler, L., Tabas, L., Villadelgado, M., Vogt, L., Evans, M., Scherer, W., Smith, M.

“…In an effort to stimulate greater emphasis on Transportation Systems Management & Operations (TSM&O), the Federal Highway Administration (FHWA) is sponsoring…”
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Cloning and Functional Characterization of the Multidrug Resistance-associated Protein (MRP1/ABCC1) from the Cynomolgus Monkey by Godinot, Nathalie, Iversen, Philip W, Tabas, Linda, Xia, Xiaoling, Williams, Daniel C, Dantzig, Anne H, Perry, 3rd, William L

“…The multidrug resistance-associated protein 1 ( ABCC1 ) gene from human (hMRP1), dog (canMRP1), and mouse (muMRP1) all encode proteins that efficiently…”
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Dipeptides as Effective Prodrugs of the Unnatural Amino Acid (+)-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylic Acid (LY354740), a Selective Group II Metabotropic Glutamate Receptor Agonist by Bueno, Ana Belén, Collado, Iván, de Dios, Alfonso, Domínguez, Carmen, Martín, José Alfredo, Martín, Luisa M, Martínez-Grau, María Angeles, Montero, Carlos, Pedregal, Concepción, Catlow, John, Coffey, D. Scott, Clay, Michael P, Dantzig, Anne H, Lindstrom, Terry, Monn, James A, Jiang, Haiyan, Schoepp, Darryle D, Stratford, Robert E, Tabas, Linda B, Tizzano, Joseph P, Wright, Rebecca A, Herin, Marc F

“…(+)-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid (1), also known as LY354740, is a highly potent and selective agonist for group II metabotropic glutamate…”
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Cyclohexyl-linked tricyclic isoxazoles are potent and selective modulators of the multidrug resistance protein (MRP1) by Norman, Bryan H., Lander, Peter A., Gruber, Joseph M., Kroin, Julian S., Cohen, Jeffrey D., Jungheim, Louis N., Starling, James J., Law, Kevin L., Self, Tracy D., Tabas, Linda B., Williams, Daniel C., Paul, Donald C., Dantzig, Anne H.

“…Novel cyclohexyl drug resistance modulators were synthesized and evaluated for in vitro inhibition of the drug resistance transporter, MRP1. This series…”
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A high-throughput assay for measurement of multidrug resistance protein-mediated transport of leukotriene C 4 into membrane vesicles by Tabas, Linda B, Dantzig, Anne H

“…This study investigated a high-throughput assay to measure multidrug resistance-associated protein (MRP1)-mediated uptake into membrane vesicles. Typically, a…”
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GSH-dependent photolabeling of multidrug resistance protein MRP1 (ABCC1) by [125I]LY475776. Evidence of a major binding site in the COOH-proximal membrane spanning domain by Mao, Qingcheng, Qiu, Wei, Weigl, Kevin E, Lander, Peter A, Tabas, Linda B, Shepard, Robert L, Dantzig, Anne H, Deeley, Roger G, Cole, Susan P C

“…Substrates transported by the 190-kDa multidrug resistance protein 1 (MRP1) (ABCC1) include endogenous organic anions such as the cysteinyl leukotriene C(4)…”
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Tricyclic isoxazoles are novel inhibitors of the multidrug resistance protein (MRP1) by NORMAN, Bryan H, GRUBER, Joseph M, WAGNER, Margaret M, DANTZIG, Anne H, HOLLINSHEAD, Sean P, WILSON, Joseph W, STARLING, James J, LAW, Kevin L, SELF, Tracy D, TABAS, Linda B, WILLIAMS, Daniel C, PAUL, Donald C

“…Tricyclic isoxazoles were identified from a screen as a novel class of selective multidrug resistance protein (MRP1) inhibitors. From a screen lead, SAR…”
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Evaluation of the binding of the tricyclic isoxazole photoaffinity label LY475776 to multidrug resistance associated protein 1 (MRP1) orthologs and several ATP-binding cassette (ABC) drug transporters by Dantzig, Anne H., Shepard, Robert L., Pratt, Susan E., Tabas, Linda B., Lander, Peter A., Ma, Liandong, Paul, Donald C., Williams, Daniel C., Peng, Sheng-Bin, Slapak, Christopher A., Godinot, Nathalie, Perry, William L.

“…Several of the ATP-binding cassette (ABC) transporters confer resistance to anticancer agents and/or antiviral agents when overexpressed in drug-sensitive…”
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Income Realization Rules for Simple Trust Beneficiaries Who Change Residence or Citizenship by Tabas, Joel L.

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