Search Results - "Tabak, Joel"

Population bursts in a modular neural network as a mechanism for synchronized activity in KNDy neurons by Blanco, Wilfredo, Tabak, Joel, Bertram, Richard

“…The pulsatile activity of gonadotropin-releasing hormone neurons (GnRH neurons) is a key factor in the regulation of reproductive hormones. This pulsatility is…”
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Ion channel noise shapes the electrical activity of endocrine cells by Richards, David M, Walker, Jamie J, Tabak, Joel

“…Endocrine cells in the pituitary gland typically display either spiking or bursting electrical activity, which is related to the level of hormone secretion…”
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Interpreting frequency responses to dose-conserved pulsatile input signals in simple cell signaling motifs by Fletcher, Patrick A, Clément, Frédérique, Vidal, Alexandre, Tabak, Joel, Bertram, Richard

“…Many hormones are released in pulsatile patterns. This pattern can be modified, for instance by changing pulse frequency, to encode relevant physiological…”
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Dynamic Clamp on a Windows PC by Milescu, Lorin S, Tabak, Joël

“…Dynamic clamp is a powerful tool for interfacing computational models and real cells. We describe here how to set up and carry out dynamic clamp experiments…”
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Mathematical Modelling of Endocrine Systems by Zavala, Eder, Wedgwood, Kyle C.A., Voliotis, Margaritis, Tabak, Joël, Spiga, Francesca, Lightman, Stafford L., Tsaneva-Atanasova, Krasimira

“…Hormone rhythms are ubiquitous and essential to sustain normal physiological functions. Combined mathematical modelling and experimental approaches have shown…”
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Ion Channels and Signaling in the Pituitary Gland by Stojilkovic, Stanko S, Tabak, Joël, Bertram, Richard

“…Endocrine pituitary cells are neuronlike; they express numerous voltage-gated sodium, calcium, potassium, and chloride channels and fire action potentials…”
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Canard-induced complex oscillations in an excitatory network by Köksal Ersöz, Elif, Desroches, Mathieu, Guillamon, Antoni, Rinzel, John, Tabak, Joël

“…In Neuroscience, mathematical modelling involving multiple spatial and temporal scales can unveil complex oscillatory activity such as excitable responses to…”
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The relationship between two fast/slow analysis techniques for bursting oscillations by Teka, Wondimu, Tabak, Joël, Bertram, Richard

“…Bursting oscillations in excitable systems reflect multi-timescale dynamics. These oscillations have often been studied in mathematical models by splitting the…”
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Is bursting more effective than spiking in evoking pituitary hormone secretion? A spatiotemporal simulation study of calcium and granule dynamics by Tagliavini, Alessia, Tabak, Joël, Bertram, Richard, Pedersen, Morten Gram

“…Endocrine cells of the pituitary gland secrete a number of hormones, and the amount of hormone released by a cell is controlled in large part by the cell's…”
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Mathematical modeling demonstrates how multiple slow processes can provide adjustable control of islet bursting by Watts, Margaret, Tabak, Joel, Bertram, Richard

“…Pancreatic islets exhibit bursting oscillations that give rise to oscillatory Ca 2+ entry and insulin secretion from β-cells. These oscillations are driven by…”
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Glucocorticoids Inhibit CRH/AVP-Evoked Bursting Activity of Male Murine Anterior Pituitary Corticotrophs by Duncan, Peter J, Tabak, Joël, Ruth, Peter, Bertram, Richard, Shipston, Michael J

“…Corticotroph cells from the anterior pituitary are an integral component of the hypothalamic-pituitary-adrenal (HPA) axis, which governs the neuroendocrine…”
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Dynamic Hormone Control of Stress and Fertility by Zavala, Eder, Voliotis, Margaritis, Zerenner, Tanja, Tabak, Joël, Walker, Jamie J, Li, Xiao Feng, Terry, John R, Lightman, Stafford L, O'Byrne, Kevin, Tsaneva-Atanasova, Krasimira

“…Neuroendocrine axes display a remarkable diversity of dynamic signaling processes relaying information between the brain, endocrine glands, and peripheral…”
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From phase advance to phase delay: Flexible coordination between neuronal rhythms by the duration of synaptic input by Borisyuk, Roman, Khibnik, Alexander, Balachandar, Arun Neru, Tabak, Joël

“…Coupled neuronal oscillators generate a wide range of dynamic activity patterns that drive various behaviors in animals. A single neural circuit can generate…”
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Large conductance Ca2+‐activated K+ (BK) channels promote secretagogue‐induced transition from spiking to bursting in murine anterior pituitary corticotrophs by Duncan, Peter J., Şengül, Sevgi, Tabak, Joël, Ruth, Peter, Bertram, Richard, Shipston, Michael J.

“…Key points Corticotroph cells of the anterior pituitary are electrically excitable and are an integral component of the hypothalamic‐pituitary‐adrenal axis…”
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Fast-activating voltage- and calcium-dependent potassium (BK) conductance promotes bursting in pituitary cells: a dynamic clamp study by Tabak, Joël, Tomaiuolo, Maurizio, Gonzalez-Iglesias, Arturo E, Milescu, Lorin S, Bertram, Richard

“…The electrical activity pattern of endocrine pituitary cells regulates their basal secretion level. Rat somatotrophs and lactotrophs exhibit spontaneous…”
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A Compartmental Model to Investigate Local and Global Ca2+ Dynamics in Astrocytes by Cresswell-Clay, Evan, Crock, Nathan, Tabak, Joël, Erlebacher, Gordon

“…Intracellular \ca dynamics in astrocytes can be triggered by neuronal activity and in turn regulate a variety of downstream processes that modulate neuronal…”
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Models of Electrical Activity: Calibration and Prediction Testing on the Same Cell by Tomaiuolo, Maurizio, Bertram, Richard, Leng, Gareth, Tabak, Joël

“…Mathematical models are increasingly important in biology, and testability is becoming a critical issue. One limitation is that one model simulation tests a…”
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A geometric understanding of how fast activating potassium channels promote bursting in pituitary cells by Vo, Theodore, Tabak, Joël, Bertram, Richard, Wechselberger, Martin

“…The electrical activity of endocrine pituitary cells is mediated by a plethora of ionic currents and establishing the role of a single channel type is…”
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The Effects of GABAergic Polarity Changes on Episodic Neural Network Activity in Developing Neural Systems by Blanco, Wilfredo, Bertram, Richard, Tabak, Joël

“…Early in development, neural systems have primarily excitatory coupling, where even GABAergic synapses are excitatory. Many of these systems exhibit…”
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Variations in the Response of Pituitary Lactotrophs to Oxytocin during the Rat Estrous Cycle by Tabak, Joël, Gonzalez-Iglesias, Arturo E, Toporikova, Natalia, Bertram, Richard, Freeman, Marc E

“…Although removal of dopamine inhibition is established as a major factor in prolactin (PRL) release, a large body of evidence suggests that hypothalamic…”
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