Search Results - "Tänzler, Dirk"

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    Mass Spectrometric Identification of SARS-CoV‑2 Proteins from Gargle Solution Samples of COVID-19 Patients by Ihling, Christian, Tänzler, Dirk, Hagemann, Sven, Kehlen, Astrid, Hüttelmaier, Stefan, Arlt, Christian, Sinz, Andrea

    Published in Journal of proteome research (06-11-2020)
    “…Mass spectrometry (MS) can deliver valuable diagnostic data that complement genomic information and allow us to increase our current knowledge of the COVID-19…”
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    Journal Article
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    A rapid and reliable liquid chromatography/mass spectrometry method for SARS-CoV-2 analysis from gargle solutions and saliva by Kipping, Marc, Tänzler, Dirk, Sinz, Andrea

    Published in Analytical and bioanalytical chemistry (01-11-2021)
    “…We describe a rapid liquid chromatography/tandem mass spectrometry (LC-MS/MS) method for the direct detection and quantitation of SARS-CoV-2 nucleoprotein in…”
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    Journal Article
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    Native mass spectrometry identifies the HybG chaperone as carrier of the Fe(CN)2CO group during maturation of E. coli [NiFe]-hydrogenase 2 by Arlt, Christian, Nutschan, Kerstin, Haase, Alexander, Ihling, Christian, Tänzler, Dirk, Sinz, Andrea, Sawers, R. Gary

    Published in Scientific reports (21-12-2021)
    “…[NiFe]-hydrogenases activate dihydrogen. Like all [NiFe]-hydrogenases, hydrogenase 2 of Escherichia coli has a bimetallic NiFe(CN) 2 CO cofactor in its…”
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    Journal Article
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    First 3D-Structural Data of Full-Length Guanylyl Cyclase 1 in Rod-Outer-Segment Preparations of Bovine Retina by Cross-Linking/Mass Spectrometry by Rehkamp, Anne, Tänzler, Dirk, Tüting, Christian, Kastritis, Panagiotis L., Iacobucci, Claudio, Ihling, Christian H., Kipping, Marc, Koch, Karl-Wilhelm, Sinz, Andrea

    Published in Journal of molecular biology (14-05-2021)
    “…[Display omitted] •3D-structural analysis of retinal guanylyl cyclase 1 was performed by XL-MS and modeling studies.•Absolute quantification and activity…”
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    Journal Article
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    Effects of theophylline on ADCY5 activation-From cellular studies to improved therapeutic options for ADCY5-related dyskinesia patients by Tänzler, Dirk, Kipping, Marc, Lederer, Marcell, Günther, Wiebke F, Arlt, Christian, Hüttelmaier, Stefan, Merkenschlager, Andreas, Sinz, Andrea

    Published in PloS one (03-03-2023)
    “…We show the effects of the three purine derivatives, caffeine, theophylline, and istradefylline, on cAMP production by adenylyl cyclase 5…”
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    Monitoring Solution Structures of Peroxisome Proliferator-Activated Receptor β/δ upon Ligand Binding by Schwarz, Rico, Tänzler, Dirk, Ihling, Christian H, Sinz, Andrea

    Published in PloS one (18-03-2016)
    “…Peroxisome proliferator-activated receptors (PPARs) have been intensively studied as drug targets to treat type 2 diabetes, lipid disorders, and metabolic…”
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    Analysis of nidogen-1/laminin γ1 interaction by cross-linking, mass spectrometry, and computational modeling reveals multiple binding modes by Lössl, Philip, Kölbel, Knut, Tänzler, Dirk, Nannemann, David, Ihling, Christian H, Keller, Manuel V, Schneider, Marian, Zaucke, Frank, Meiler, Jens, Sinz, Andrea

    Published in PloS one (11-11-2014)
    “…We describe the detailed structural investigation of nidogen-1/laminin γ1 complexes using full-length nidogen-1 and a number of laminin γ1 variants. The…”
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    Monitoring Conformational Changes in Peroxisome Proliferator-Activated Receptor α by a Genetically Encoded Photoamino Acid, Cross-Linking, and Mass Spectrometry by Schwarz, Rico, Tänzler, Dirk, Ihling, Christian H, Müller, Mathias Q, Kölbel, Knut, Sinz, Andrea

    Published in Journal of medicinal chemistry (13-06-2013)
    “…Chemical cross-linking combined with an enzymatic digestion and mass spectrometric analysis of the reaction products has evolved into an alternative strategy…”
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  10. 10

    Molecular Details of Retinal Guanylyl Cyclase 1/GCAP-2 Interaction by Rehkamp, Anne, Tänzler, Dirk, Iacobucci, Claudio, Golbik, Ralph P, Ihling, Christian H, Sinz, Andrea

    Published in Frontiers in molecular neuroscience (19-09-2018)
    “…The rod outer segment guanylyl cyclase 1 (ROS-GC1) is an essential component of photo-transduction in the retina. In the light-induced signal cascade,…”
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    Journal Article
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    Monitoring Solution Structures of Peroxisome Proliferator-Activated Receptor [beta]/[delta] upon Ligand Binding by Schwarz, Rico, Tänzler, Dirk, Ihling, Christian H, Sinz, Andrea

    Published in PloS one (18-03-2016)
    “…Peroxisome proliferator-activated receptors (PPARs) have been intensively studied as drug targets to treat type 2 diabetes, lipid disorders, and metabolic…”
    Get full text
    Journal Article
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    Native mass spectrometry identifies the HybG chaperone as carrier of the Fe(CN) 2 CO group during maturation of E. coli [NiFe]-hydrogenase 2 by Arlt, Christian, Nutschan, Kerstin, Haase, Alexander, Ihling, Christian, Tänzler, Dirk, Sinz, Andrea, Sawers, R Gary

    Published in Scientific reports (21-12-2021)
    “…[NiFe]-hydrogenases activate dihydrogen. Like all [NiFe]-hydrogenases, hydrogenase 2 of Escherichia coli has a bimetallic NiFe(CN) CO cofactor in its catalytic…”
    Get full text
    Journal Article
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    Analysis of Nidogen-1/Laminin [gamma]1 Interaction by Cross-Linking, Mass Spectrometry, and Computational Modeling Reveals Multiple Binding Modes by Lössl, Philip, Kölbel, Knut, Tänzler, Dirk, Nannemann, David, Ihling, Christian H, Keller, Manuel V, Schneider, Marian, Zaucke, Frank, Meiler, Jens, Sinz, Andrea

    Published in PloS one (11-11-2014)
    “…We describe the detailed structural investigation of nidogen-1/laminin [gamma]1 complexes using full-length nidogen-1 and a number of laminin [gamma]1…”
    Get full text
    Journal Article
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