Search Results - "Tağ, Özgür"
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Biotransformation of Neoruscogenin by the Endophytic Fungus Alternaria eureka
Published in Journal of natural products (Washington, D.C.) (22-06-2018)“…Biotransformation of neoruscogenin (NR, 1, spirosta-5,25(27)-diene-1β,3β-diol), the major bioactive sapogenin of Ruscus preparations, was carried out with the…”
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Identification of a Noncanonical Necrotic Cell Death Triggered via Enhanced Proteolysis by a Novel Sapogenol Derivative
Published in Chemical research in toxicology (16-11-2020)“…Small molecules which activate distinct cell death pathways have promising high potential for anticancer drug research. Especially, regulated necrosis draws…”
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Biotransformation of ruscogenins by Cunninghamella blakesleeana NRRL 1369 and neoruscogenin by endophytic fungus Neosartorya hiratsukae
Published in Phytochemistry (Oxford) (01-08-2018)“…Biotransformation of steroidal ruscogenins (neoruscogenin and ruscogenin) was carried out with Cunninghamella blakesleeana NRRL 1369 and endophytic fungus…”
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Cycloartane-type sapogenol derivatives inhibit NFκB activation as chemopreventive strategy for inflammation-induced prostate carcinogenesis
Published in Steroids (01-07-2018)“…•9,19-cyclolanostane derivatives starting from cycloastragenol were synthesized.•Five analogs were selected to be screened for their anti-inflammatory…”
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Cleavage of ring A and formation of an unusual nor-triterpene skeleton via the Baeyer–Villiger reaction
Published in Tetrahedron letters (31-10-2012)“…With the aim to generate a compound library for our biological screening studies, cycloastragenol was subjected to chemical transformation studies. The…”
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Microbial transformation of Astragalus sapogenins using Cunninghamella blakesleeana NRRL 1369 and Glomerella fusarioides ATCC 9552
Published in Journal of molecular catalysis. B, Enzymatic (01-05-2015)“…•Microbial transformations of Astragalus saponins were investigated.•Two fungi were used as whole cell systems.•Each organism led to characteristic…”
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A comparative study on extraction processes of Stevia rebaudiana leaves with emphasis on antioxidant, cytotoxic and nitric oxide inhibition activities
Published in Industrial crops and products (23-12-2015)“…[Display omitted] •Stevia leaves were extracted with microwave (MAE) and ultrasonically assisted extraction (UAE).•About 21.21 and 19.90mg glycosides/g dried…”
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Subcritical water extraction of steviol glycosides from Stevia rebaudiana leaves and characterization of the raffinate phase
Published in The Journal of supercritical fluids (01-11-2014)“…•Stevia rebaudiana leaves were subjected to subcritical water.•Yielding 38.67mg stevioside and 35.68mg rebaudioside A per g dry leaves.•Raffinate phase was…”
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Effect of a New Sapogenol Derivative (AG-07) on Cell Death via Necrosis
Published in Proceedings (01-11-2017)“…Saponins, plant secondary metabolites with high molecular weight, carry sugar groups on the triterpenic or steroidal skeleton. They exhibit biological…”
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Characterization of Cycloartane-Type Sapogenol Derivatives for Prostate Cancer Chemoprevention
Published in Proceedings (01-11-2017)“…Inhibition of inflammation-induced carcinogenesis is an efficient therapeutic strategy for cancer chemoprevention as use of anti-inflammatories was reported to…”
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