Search Results - "TUSCANO, Daniela"

A2A adenosine receptor ligands and proinflammatory cytokines induce PC 12 cell death through apoptosis by TRINCAVELLI, Maria L, FALLENI, Alessandra, CHELLI, Beatrice, TUSCANO, Daniela, COSTA, Barbara, GREMIGNI, Vittorio, LUCACCHINI, Antonio, MARTINI, Claudia

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Regulation of A2B adenosine receptor functioning by tumour necrosis factor a in human astroglial cells by Trincavelli, Maria L., Marroni, Matteo, Tuscano, Daniela, Ceruti, Stefania, Mazzola, Alessia, Mitro, Nico, Abbracchio, Maria P., Martini, Claudia

“…Low‐affinity A2B adenosine receptors (A2B ARs), which are expressed in astrocytes, are mainly activated during brain hypoxia and ischaemia, when large amounts…”
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2-(Benzimidazol-2-yl)quinoxalines:  A Novel Class of Selective Antagonists at Human A1 and A3 Adenosine Receptors Designed by 3D Database Searching by Novellino, Ettore, Cosimelli, Barbara, Ehlardo, Marina, Greco, Giovanni, Iadanza, Manuela, Lavecchia, Antonio, Rimoli, Maria Grazia, Sala, Annalisa, Da Settimo, Antonio, Primofiore, Giampaolo, Da Settimo, Federico, Taliani, Sabrina, La Motta, Concettina, Klotz, Karl-Norbert, Tuscano, Daniela, Trincavelli, Maria Letizia, Martini, Claudia

“…The Cambridge Structural Database (CSD) was searched through two 3D queries based on substructures shared by well-known antagonists at the A1 and A3 adenosine…”
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Novel, Highly Potent Adenosine Deaminase Inhibitors Containing the Pyrazolo[3,4-d]pyrimidine Ring System. Synthesis, Structure−Activity Relationships, and Molecular Modeling Studies by Da Settimo, Federico, Primofiore, Giampaolo, La Motta, Concettina, Taliani, Sabrina, Simorini, Francesca, Marini, Anna Maria, Mugnaini, Laura, Lavecchia, Antonio, Novellino, Ettore, Tuscano, Daniela, Martini, Claudia

“…This study reports the synthesis of a number of 1- and 2-alkyl derivatives of the 4-aminopyrazolo[3,4-d]pyrimidine (APP) nucleus and their evaluation as…”
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2-(Benzimidazol-2-yl)quinoxalines: a novel class of selective antagonists at human A(1) and A(3) adenosine receptors designed by 3D database searching by Novellino, Ettore, Cosimelli, Barbara, Ehlardo, Marina, Greco, Giovanni, Iadanza, Manuela, Lavecchia, Antonio, Rimoli, Maria Grazia, Sala, Annalisa, Da Settimo, Antonio, Primofiore, Giampaolo, Da Settimo, Federico, Taliani, Sabrina, La Motta, Concettina, Klotz, Karl-Norbert, Tuscano, Daniela, Trincavelli, Maria Letizia, Martini, Claudia

“…The Cambridge Structural Database (CSD) was searched through two 3D queries based on substructures shared by well-known antagonists at the A(1) and A(3)…”
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Up-regulation of A2A adenosine receptors by proinflammatory cytokines in rat PC12 cells by TRINCAVELLI, Maria L, COSTA, Barbara, TUSCANO, Daniela, LUCACCHINI, Antonio, MARTINI, Claudia

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Involvement of mitogen protein kinase cascade in agonist-mediated human A3 adenosine receptor regulation by Trincavelli, M.Letizia, Tuscano, Daniela, Marroni, Matteo, Klotz, Karl-Norbert, Lucacchini, Antonio, Martini, Claudia

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Up-regulation of A(2A) adenosine receptors by proinflammatory cytokines in rat PC12 cells by Trincavelli, Maria L, Costa, Barbara, Tuscano, Daniela, Lucacchini, Antonio, Martini, Claudia

“…The purpose of this study was to examine the regulation of A(2A) adenosine receptor (A(2A) AR) gene expression induced by proinflammatory cytokines in PC12…”
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Upregulation of A2A adenosine receptors in platelets from patients affected by bipolar disorders under treatment with typical antipsychotics by MARTINI, Claudia, TUSCANO, Daniela, BATTISTA CASSANO, Giovanni, DELL'OSSO, Liliana, LETIZIA TRINCAVELLI, Maria, CERRAI, Elisa, BIANCHI, Maria, CIAPPARELLI, Antonio, ALESSIO, Lucioni, NOVELLI, Letizia, CATENA, Mario, LUCACCHINI, Antonio

“…Antipsychotic drugs, potent dopamine receptor antagonists, are commonly used in the treatment of psychotic and affective illness. The discovery of antagonistic…”
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Differences in the neurotoxicity profile induced by ATP and ATPγS in cultured cerebellar granule neurons by Amadio, Susanna, D’Ambrosi, Nadia, Trincavelli, Maria Letizia, Tuscano, Daniela, Sancesario, Giuseppe, Bernardi, Giorgio, Martini, Claudia, Volonté, Cinzia

“…Extracellular ATP and P2 receptors may play a crucial role in the neurodegeneration of the CNS. Here, we investigated in neuronal cerebellar granule cultures…”
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Involvement of mitogen protein kinase cascade in agonist-mediated human A(3) adenosine receptor regulation by Trincavelli, M Letizia, Tuscano, Daniela, Marroni, Matteo, Klotz, Karl-Norbert, Lucacchini, Antonio, Martini, Claudia

“…It has been suggested that A(3) adenosine receptors (ARs) play a role in the pathophysiology of cerebral ischemia with dual and opposite neuroprotective and…”
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Design, Synthesis and Biological Evaluation of Novel N-Alkyl- and N-Acyl-(7-substituted-2-phenylimidazo[1,2-a][1,3,5]triazin-4-yl)amines (ITAs) as Novel A1 Adenosine Receptor Antagonists by Novellino, Ettore, Abignente, Enrico, Cosimelli, Barbara, Greco, Giovanni, Iadanza, Manuela, Laneri, Sonia, Lavecchia, Antonio, Rimoli, Maria Grazia, Settimo, Federico Da, Primofiore, Giampaolo, Tuscano, Daniela, Trincavelli, Letizia, Martini, Claudia

“…Prompted by pharmacophore and docking based models, we have synthesized and tested a number of N-alkyl and…”
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Differences in the neurotoxicity profile induced by ATP and ATPgammaS in cultured cerebellar granule neurons by Amadio, Susanna, D'Ambrosi, Nadia, Trincavelli, Maria Letizia, Tuscano, Daniela, Sancesario, Giuseppe, Bernadi, Giorgio, Martini, Claudia, Volonté, Cinzia

“…Extracellular ATP and P2 receptors may play a crucial role in the neurodegeneration of the CNS. Here, we investigated in neuronal cerebellar granule cultures…”
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Design, synthesis and biological evaluation of novel N-alkyl- and N-acyl-(7-substituted-2-phenylimidazo[1,2-a][1,3,5]triazin-4-yl)amines (ITAs) as novel A(1) adenosine receptor antagonists by Novellino, Ettore, Abignente, Enrico, Cosimelli, Barbara, Greco, Giovanni, Iadanza, Manuela, Laneri, Sonia, Lavecchia, Antonio, Rimoli, Maria Grazia, Settimo, Federico Da, Primofiore, Giampaolo, Tuscano, Daniela, Trincavelli, Letizia, Martini, Claudia

“…Prompted by pharmacophore and docking based models, we have synthesized and tested a number of N-alkyl and…”
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A(2A) adenosine receptor ligands and proinflammatory cytokines induce PC 12 cell death through apoptosis by Trincavelli, Maria L, Falleni, Alessandra, Chelli, Beatrice, Tuscano, Daniela, Costa, Barbara, Gremigni, Vittorio, Lucacchini, Antonio, Martini, Claudia

“…A(2A) adenosine receptor-mediated signaling affects a variety of important processes in the central nervous system both in physiological and pathological…”
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Upregulation of A 2A adenosine receptors in platelets from patients affected by bipolar disorders under treatment with typical antipsychotics by Martini, Claudia, Tuscano, Daniela, Trincavelli, Maria Letizia, Cerrai, Elisa, Bianchi, Maria, Ciapparelli, Antonio, Alessio, Lucioni, Novelli, Letizia, Catena, Mario, Lucacchini, Antonio, Cassano, Giovanni Battista, Dell’Osso, Liliana

“…Antipsychotic drugs, potent dopamine receptor antagonists, are commonly used in the treatment of psychotic and affective illness. The discovery of antagonistic…”
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Serotonin-mediated phosphorylation of extracellular regulated kinases in platelets of patients with panic disorder versus controls by Martini, Claudia, Trincavelli, Maria Letizia, Tuscano, Daniela, Carmassi, Claudia, Ciapparelli, Antonio, Lucacchini, Antonio, Cassano, Giovanni Battista, Dell’Osso, Liliana

“…Phosphorylation of extracellular signal-regulated kinases (ERK 1/2) represents a converging intracellular signalling pathway which is involved in the…”
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2-(Benzimidazol-2-yl)quinoxalines:  A Novel Class of Selective Antagonists at Human A 1 and A 3 Adenosine Receptors Designed by 3D Database Searching by Novellino, Ettore, Cosimelli, Barbara, Ehlardo, Marina, Greco, Giovanni, Iadanza, Manuela, Lavecchia, Antonio, Rimoli, Maria Grazia, Sala, Annalisa, Da Settimo, Antonio, Primofiore, Giampaolo, Da Settimo, Federico, Taliani, Sabrina, La Motta, Concettina, Klotz, Karl-Norbert, Tuscano, Daniela, Trincavelli, Maria Letizia, Martini, Claudia

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A1 adenosine receptor antagonists, 3-aryl[1,2,4]triazino[4,3-a]benzimidazol-4-(10H)-ones (ATBIs) and N-alkyl and N-acyl-(7-substituted-2-phenylimidazo[1,2-a][1,3,5]triazin-4-yl)amines (ITAs): Different recognition of bovine and human binding sites by Da Settimo, Federico, Primofiore, Giampaolo, Taliani, Sabrina, La Motta, Concettina, Novellino, Ettore, Greco, Giovanni, Lavecchia, Antonio, Cosimelli, Barbara, Iadanza, Manuela, Klotz, Karl-Norbert, Tuscano, Daniela, Trincavelli, Maria Letizia, Martini, Claudia

“…3‐Aryl[1,2,4]triazino[4,3‐a]benzimidazol‐4‐(10H)‐ones (ATBIs) 1 and N‐alkyl and N‐acyl‐(7‐substituted‐2‐phenylimidazo[1,2‐a][1,3,5]triazin‐4‐yl)amines (ITAs)…”
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A 2A adenosine receptor ligands and proinflammatory cytokines induce PC 12 cell death through apoptosis by Trincavelli, Maria L., Falleni, Alessandra, Chelli, Beatrice, Tuscano, Daniela, Costa, Barbara, Gremigni, Vittorio, Lucacchini, Antonio, Martini, Claudia

“…A 2A adenosine receptor-mediated signaling affects a variety of important processes in the central nervous system both in physiological and pathological…”
Get full text