Search Results - "TURTON, Jane"

Multiresistant Gram-negative bacteria: the role of high-risk clones in the dissemination of antibiotic resistance by Woodford, Neil, Turton, Jane F., Livermore, David M.

“…Abstract Multilocus sequence typing reveals that many bacterial species have a clonal structure and that some clones are widespread. This underlying phylogeny…”
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Do plasmids containing heavy metal resistance genes play a role in neonatal sepsis and invasive disease caused by Klebsiella pneumoniae and Klebsiella variicola? by Turton, Jane F., Perry, Claire, Claxton, Alleyna

“…Introduction. Klebsiella species are some of those most implicated in neonatal sepsis. However, many isolates from infections appear unremarkable; they are…”
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Virulence genes in isolates of Klebsiella pneumoniae from the UK during 2016, including among carbapenemase gene-positive hypervirulent K1-ST23 and 'non-hypervirulent' types ST147, ST15 and ST383 by Turton, Jane F, Payne, Zoë, Coward, Amy, Hopkins, Katie L, Turton, Jack A, Doumith, Michel, Woodford, Neil

“…Klebsiella pneumoniae is a concern because of its multidrug resistance and the ability of hypervirulent types, especially capsular type K1-clonal complex 23…”
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PCR characterization and typing of Klebsiella pneumoniae using capsular type-specific, variable number tandem repeat and virulence gene targets by TURTON, Jane F, PERRY, Claire, ELGOHARI, Suzanne, HAMPTON, Catherine V

“…A multiplex PCR is described which detects capsular types K1, K2, K5, K54 and K57, which are those most associated with invasive disease or pathogenicity, a…”
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Incidence of Acinetobacter Species Other than A. baumannii among Clinical Isolates of Acinetobacter: Evidence for Emerging Species by Turton, Jane F, Shah, Jayesh, Ozongwu, Chika, Pike, Rachel

“…Six hundred ninety nonduplicate isolates of Acinetobacter species were identified using a combination of detection of blaOXA₋₅₁₋like and rpoB sequence cluster…”
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Klebsiella pneumoniae sequence type 147: a high-risk clone increasingly associated with plasmids carrying both resistance and virulence elements by Turton, Jane F, Perry, Claire, McGowan, Kim, Turton, Jack A, Hope, Russell

“…The first hybrid resistance/virulence plasmid, combining elements from virulence plasmids described in hypervirulent types of with those from conjugative…”
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Clonal expansion of Escherichia coli ST38 carrying a chromosomally integrated OXA-48 carbapenemase gene by Turton, Jane F, Doumith, Michel, Hopkins, Katie L, Perry, Claire, Meunier, Daniele, Woodford, Neil

“…Many isolates of Escherichia coli carrying blaOXA-48 referred to Public Health England's national reference laboratory during 2014 and 2015 shared similar…”
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Dominance of international 'high-risk clones' among metallo-β-lactamase-producing Pseudomonas aeruginosa in the UK by Wright, Laura L, Turton, Jane F, Livermore, David M, Hopkins, Katie L, Woodford, Neil

“…Carbapenem-resistant isolates of Pseudomonas aeruginosa producing metallo-β-lactamases (MBLs) are increasingly reported worldwide and often belong to…”
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Waterborne Elizabethkingia meningoseptica in Adult Critical Care by Moore, Luke S P, Owens, Daniel S, Jepson, Annette, Turton, Jane F, Ashworth, Simon, Donaldson, Hugo, Holmes, Alison H

“…Elizabethkingia meningoseptica is an infrequent colonizer of the respiratory tract; its pathogenicity is uncertain. In the context of a 22-month outbreak of E…”
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A Multispecies Cluster of GES-5 Carbapenemase–Producing Enterobacterales Linked by a Geographically Disseminated Plasmid by Ellington, Matthew J, Davies, Frances, Jauneikaite, Elita, Hopkins, Katie L, Turton, Jane F, Adams, George, Pavlu, Jiri, Innes, Andrew J, Eades, Christopher, Brannigan, Eimear T, Findlay, Jacqueline, White, Leila, Bolt, Frances, Kadhani, Tokozani, Chow, Yimmy, Patel, Bharat, Mookerjee, Siddharth, Otter, Jonathan A, Sriskandan, Shiranee, Woodford, Neil, Holmes, Alison

“…Abstract Background Early and accurate treatment of infections due to carbapenem-resistant organisms is facilitated by rapid diagnostics, but rare resistance…”
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Covert dissemination of carbapenemase-producing Klebsiella pneumoniae (KPC) in a successfully controlled outbreak: long- and short-read whole-genome sequencing demonstrate multiple genetic modes of transmission by Martin, Jessica, Phan, Hang T T, Findlay, Jacqueline, Stoesser, Nicole, Pankhurst, Louise, Navickaite, Indre, De Maio, Nicola, Eyre, David W, Toogood, Giles, Orsi, Nicolas M, Kirby, Andrew, Young, Nicola, Turton, Jane F, Hill, Robert L R, Hopkins, Katie L, Woodford, Neil, Peto, Tim E A, Walker, A Sarah, Crook, Derrick W, Wilcox, Mark H

“…Carbapenemase-producing Enterobacteriaceae (CPE), including KPC-producing Klebsiella pneumoniae (KPC-Kpn), are an increasing threat to patient safety. To use…”
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Emergence of a new antibiotic resistance mechanism in India, Pakistan, and the UK: a molecular, biological, and epidemiological study by Kumarasamy, Karthikeyan K, MPhil, Toleman, Mark A, PhD, Walsh, Timothy R, Prof, Bagaria, Jay, MD, Butt, Fafhana, MD, Balakrishnan, Ravikumar, MD, Chaudhary, Uma, MD, Doumith, Michel, PhD, Giske, Christian G, MD, Irfan, Seema, MD, Krishnan, Padma, PhD, Kumar, Anil V, MD, Maharjan, Sunil, MD, Mushtaq, Shazad, MD, Noorie, Tabassum, MD, Paterson, David L, MD, Pearson, Andrew, PhD, Perry, Claire, PhD, Pike, Rachel, PhD, Rao, Bhargavi, MD, Ray, Ujjwayini, MD, Sarma, Jayanta B, MD, Sharma, Madhu, MD, Sheridan, Elizabeth, PhD, Thirunarayan, Mandayam A, MD, Turton, Jane, PhD, Upadhyay, Supriya, PhD, Warner, Marina, PhD, Welfare, William, PhD, Livermore, David M, PhD, Woodford, Neil, PhD

“…Summary Background Gram-negative Enterobacteriaceae with resistance to carbapenem conferred by New Delhi metallo-β-lactamase 1 (NDM-1) are potentially a major…”
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Prevalence of Burkholderia species, including members of Burkholderia cepacia complex, among UK cystic and non-cystic fibrosis patients by Kenna, Dervla T D, Lilley, Daniel, Coward, Amy, Martin, Kate, Perry, Claire, Pike, Rachel, Hill, Robert, Turton, Jane F

“…We aimed to establish the prevalence of different Burkholderia species among UK cystic fibrosis (CF) and non-CF patients over a 2 year period. Matrix-assisted…”
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The role of ISAba1 in expression of OXA carbapenemase genes in Acinetobacter baumannii by Turton, Jane F., Ward, M. Elaina, Woodford, Neil, Kaufmann, Mary E., Pike, Rachel, Livermore, David M., Pitt, Tyrone L.

“…Abstract ISAba1 was found in all widespread clones of Acinetobacter baumannii in the United Kingdom. All isolates studied had a blaOXA-51-like carbapenemase…”
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Wide distribution of Escherichia coli carrying IncF plasmids containing bla NDM-5 and rmtB resistance genes from hospitalized patients in England by Turton, Jane F., Pike, Rachel, Perry, Claire, Jenkins, Claire, Turton, Jack A., Meunier, Danièle, Hopkins, Katie L

“…Introduction . The New Delhi metallo-β-lactamase (NDM) variant NDM-5 was first described in 2011 in an isolate of Escherichia coli . We noted that a high…”
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Emergence and clonal spread of colistin resistance due to multiple mutational mechanisms in carbapenemase-producing Klebsiella pneumoniae in London by Otter, Jonathan A., Doumith, Michel, Davies, Frances, Mookerjee, Siddharth, Dyakova, Eleonora, Gilchrist, Mark, Brannigan, Eimear T., Bamford, Kathleen, Galletly, Tracey, Donaldson, Hugo, Aanensen, David M., Ellington, Matthew J., Hill, Robert, Turton, Jane F., Hopkins, Katie L., Woodford, Neil, Holmes, Alison

“…Carbapenemase-producing Enterobacteriaceae (CPE) are emerging worldwide, limiting therapeutic options. Mutational and plasmid-mediated mechanisms of colistin…”
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Hybrid Resistance and Virulence Plasmids in “High-Risk” Clones of Klebsiella pneumoniae, Including Those Carrying blaNDM-5 by Turton, Jane, Davies, Frances, Turton, Jack, Perry, Claire, Payne, Zoë, Pike, Rachel

“…Virulence plasmids are associated with hypervirulent types of Klebsiella pneumoniae, which generally do not carry antibiotic resistance genes. In contrast,…”
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Association of Novel Nonsynonymous Single Nucleotide Polymorphisms in ampD with Cephalosporin Resistance and Phylogenetic Variations in ampC, ampR, ompF, and ompC in Enterobacter cloacae Isolates That Are Highly Resistant to Carbapenems by Babouee Flury, Baharak, Ellington, Matthew J, Hopkins, Katie L, Turton, Jane F, Doumith, Michel, Loy, Richard, Staves, Peter, Hinic, Vladimira, Frei, Reno, Woodford, Neil

“…InEnterobacter cloacae, the genetic lesions associated with derepression of the AmpC β-lactamase include diverse single nucleotide polymorphisms (SNPs) and/or…”
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Efflux Pumps, OprD Porin, AmpC β-Lactamase, and Multiresistance in Pseudomonas aeruginosa Isolates from Cystic Fibrosis Patients by TOMAS, Maria, DOUMITH, Michel, WARNER, Marina, TURTON, Jane F, BECEIRO, Alejandro, BOU, German, LIVERMORE, David M, WOODFORD, Neil

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Integrated Analysis of Patient Networks and Plasmid Genomes to Investigate a Regional, Multispecies Outbreak of Carbapenemase-Producing Enterobacterales Carrying Both blaIMP and mcr-9 Genes by Wan, Yu, Myall, Ashleigh C, Boonyasiri, Adhiratha, Bolt, Frances, Ledda, Alice, Mookerjee, Siddharth, Weiße, Andrea Y, Getino, Maria, Turton, Jane F, Abbas, Hala, Prakapaite, Ruta, Sabnis, Akshay, Abdolrasouli, Alireza, Malpartida-Cardenas, Kenny, Miglietta, Luca, Donaldson, Hugo, Gilchrist, Mark, Hopkins, Katie L, Ellington, Matthew J, Otter, Jonathan A, Larrouy-Maumus, Gerald, Edwards, Andrew M, Rodriguez-Manzano, Jesus, Didelot, Xavier, Barahona, Mauricio, Holmes, Alison H, Jauneikaite, Elita, Davies, Frances

“…Carbapenemase-producing Enterobacterales (CPE) are challenging in healthcare, with resistance to multiple classes of antibiotics. This study describes the…”
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