Search Results - "TURNER, Robert S"
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1
Basal ganglia contributions to motor control: a vigorous tutor
Published in Current opinion in neurobiology (01-12-2010)“…The roles of the basal ganglia (BG) in motor control are much debated. Many influential hypotheses have grown from studies in which output signals of the BG…”
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2
Limited encoding of effort by dopamine neurons in a cost-benefit trade-off task
Published in The Journal of neuroscience (08-05-2013)“…Animals are thought to evaluate the desirability of action options using a unified scale that combines predicted benefits ("rewards"), costs, and the animal's…”
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3
Primary motor cortex of the parkinsonian monkey: differential effects on the spontaneous activity of pyramidal tract-type neurons
Published in Cerebral cortex (New York, N.Y. 1991) (01-06-2011)“…Dysfunction of primary motor cortex (M1) is thought to contribute to the pathophysiology of parkinsonism. What specific aspects of M1 function are abnormal…”
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4
Primary motor cortex of the parkinsonian monkey: altered encoding of active movement
Published in Brain (London, England : 1878) (01-01-2016)“…Abnormalities in the movement-related activation of the primary motor cortex (M1) are thought to be a major contributor to the motor signs of Parkinson's…”
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5
Toward Electrophysiology-Based Intelligent Adaptive Deep Brain Stimulation for Movement Disorders
Published in Neurotherapeutics (01-01-2019)“…Deep brain stimulation (DBS) represents one of the major clinical breakthroughs in the age of translational neuroscience. In 1987, Benabid and colleagues…”
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6
A selective role for ventromedial subthalamic nucleus in inhibitory control
Published in eLife (04-12-2017)“…The subthalamic nucleus (STN) is hypothesized to play a central role in the rapid stopping of movement in reaction to a stop signal. Single-unit recording…”
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7
Dopamine neurons encode errors in predicting movement trigger occurrence
Published in Journal of neurophysiology (15-02-2015)“…The capacity to anticipate the timing of events in a dynamic environment allows us to optimize the processes necessary for perceiving, attending to, and…”
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8
Neural dynamics underlying self-control in the primate subthalamic nucleus
Published in eLife (19-05-2023)“…The subthalamic nucleus (STN) is hypothesized to play a central role in neural processes that regulate self-control. Still uncertain, however, is how that…”
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9
Chunking as the result of an efficiency computation trade-off
Published in Nature communications (11-07-2016)“…How to move efficiently is an optimal control problem, whose computational complexity grows exponentially with the horizon of the planned trajectory. Breaking…”
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10
Movement-related dynamics of cortical oscillations in Parkinson's disease and essential tremor
Published in Brain (London, England : 1878) (01-08-2016)“…Recent electrocorticography data have demonstrated excessive coupling of beta-phase to gamma-amplitude in primary motor cortex and that deep brain stimulation…”
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11
Electrocorticography is superior to subthalamic local field potentials for movement decoding in Parkinson's disease
Published in eLife (27-05-2022)“…Brain signal decoding promises significant advances in the development of clinical brain computer interfaces (BCI). In Parkinson's disease (PD), first…”
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12
Neural activity during a simple reaching task in macaques is counter to gating and rebound in basal ganglia-thalamic communication
Published in PLoS biology (13-10-2020)“…Task-related activity in the ventral thalamus, a major target of basal ganglia output, is often assumed to be permitted or triggered by changes in basal…”
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13
Deep Brain Stimulation of the Globus Pallidus Internus in the Parkinsonian Primate: Local Entrainment and Suppression of Low-Frequency Oscillations
Published in Journal of neurophysiology (01-04-2009)“…1 Departments of Neurobiology and Bioengineering and The Center for the Neural Basis of Cognition, University of Pittsburgh, Pittsburgh, Pennsylvania; 2…”
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14
Axonal and synaptic failure suppress the transfer of firing rate oscillations, synchrony and information during high frequency deep brain stimulation
Published in Neurobiology of disease (01-02-2014)“…Abstract High frequency deep brain stimulation (DBS) of the subthalamic nucleus (STN) is a widely used treatment for Parkinson's disease, but its effects on…”
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15
Pallidal stimulation suppresses pathological dysrhythmia in the parkinsonian motor cortex
Published in Journal of neurophysiology (01-04-2015)“…Although there is general consensus that deep brain stimulation (DBS) yields substantial clinical benefit in patients with Parkinson's disease (PD), the…”
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16
Hyperdirect connectivity of opercular speech network to the subthalamic nucleus
Published in Cell reports (Cambridge) (08-03-2022)“…How the basal ganglia participate in the uniquely human behavior of speech is poorly understood, despite their known role in modulating critical aspects of…”
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17
A neurocomputational view of the effects of Parkinson's disease on speech production
Published in Frontiers in human neuroscience (15-05-2024)“…The purpose of this article is to review the scientific literature concerning speech in Parkinson's disease (PD) with reference to the DIVA/GODIVA…”
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Cortical oscillatory dysfunction in Parkinson disease during movement activation and inhibition
Published in PloS one (04-03-2022)“…Response activation and inhibition are functions fundamental to executive control that are disrupted in Parkinson disease (PD). We used magnetoencephalography…”
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19
Movement-related coupling of human subthalamic nucleus spikes to cortical gamma
Published in eLife (11-03-2020)“…Cortico-basal ganglia interactions continuously shape the way we move. Ideas about how this circuit works are based largely on models those consider only…”
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20
Movement-related discharge in the macaque globus pallidus during high-frequency stimulation of the subthalamic nucleus
Published in The Journal of neuroscience (04-03-2015)“…Deep brain stimulation (DBS) of the subthalamic nucleus (STN-DBS) has largely replaced ablative therapies for Parkinson's disease. Because of the similar…”
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