Search Results - "TURLEY, S. J."

Transport of Peptide: MHC Class II Complexes in Developing Dendritic Cells by Turley, Shannon J., Inaba, Kayo, Garrett, Wendy S., Ebersold, Melanie, Unternaehrer, Julia, Steinman, Ralph M., Mellman, Ira

“…Major histocompatibility complex class II (MHC II) molecules capture peptides within the endocytic pathway to generate T cell receptor (TCR) ligands. Immature…”
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Developmental regulation of MHC class II transport in mouse dendritic cells by Mellman, Ira, Pierre, Philippe, Turley, Shannon J, Gatti, Evelina, Hull, Michael, Meltzer, Joseph, Mirza, Asra, Inaba, Kayo, Steinman, Ralph M

“…Dendritic cells (DCs) have the unique capacity to initiate primary and secondary immune responses. They acquire antigens in peripheral tissues and migrate to…”
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Transcriptomic analysis of hepatocellular carcinoma reveals molecular features of disease progression and tumor immune biology by Okrah, K., Tarighat, S., Liu, B., Koeppen, H., Wagle, M. C., Cheng, G., Sun, C., Dey, A., Chang, M. T., Sumiyoshi, T., Mounir, Z., Cummings, C., Hampton, G., Amler, L., Fridlyand, J., Hegde, P. S., Turley, S. J., Lackner, M. R., Huang, S. M.

“…Hepatocellular carcinoma (HCC) develops in the context of chronic inflammatory liver disease and has an extremely poor prognosis. An immunosuppressive tumor…”
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Projection of an Immunological Self Shadow within the Thymus by the Aire Protein by Anderson, Mark S., Venanzi, Emily S., Klein, Ludger, Chen, Zhibin, Berzins, Stuart P., Turley, Shannon J., von Boehmer, Harald, Bronson, Roderick, Dierich, Andrée, Benoist, Christophe, Mathis, Diane

“…Humans expressing a defective form of the transcription factor AIRE (autoimmune regulator) develop multiorgan autoimmune disease. We used airedeficient mice to…”
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Analysis of the autoantibody response to fibrillarin in human disease and murine models of autoimmunity by Takeuchi, K, Turley, SJ, Tan, EM, Pollard, KM

“…Fibrillarin, a component of the U3 RNP particle, is a target for the spontaneously arising autoantibodies in human scleroderma and a monoclonal autoantibody…”
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Selective induction of anti‐fibrillarin autoantibodies by silver nitrate in mice by HULTMAN, P., ENESTRöM, S., TURLEY, S. J., POLLARD, K. M.

“…SUMMARY Female SJL (H‐2s) mice developed serum IgG anti‐nucleolar antibodies (ANoA) after 5 weeks treatment with 0·05% or 0·01% silver nitrate (AgNO3) in…”
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Murine Genotype Influences the Specificity, Magnitude and Persistence of Murine Mercury-Induced Autoimmunity by Hultman, Per, Turley, Shannon J., Eneström, Sverker, Lindh, Ulf, Pollard, Michael K.

“…Genetic factors are major contributors in determining the susceptibility to systemic autoimmune diseases. We studied the influence of genotype on systemic…”
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Illegal shooting is now a leading cause of death of birds along power lines in the western USA by Thomason, Eve C., Turley, Natalie J.S., Belthoff, James R., Conkling, Tara J., Katzner, Todd E.

“…Human actions, both legal and illegal, affect wildlife in many ways. Inaccurate diagnosis of cause of death undermines law enforcement, management, threat…”
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Dendritic cells: inciting and inhibiting autoimmunity by Turley, Shannon J

“…Dendritic cells are considered the most influential antigen presenting cells in the body because of their unique role in initiating immunity against…”
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Self-encounters of the third kind: lymph node stroma promotes tolerance to peripheral tissue antigens by Collier, A Y, Lee, J-W, Turley, S J

“…Multiple mechanisms have evolved to maintain tolerance among CD8 + T cells to innocuous antigens that arise in cutaneous and mucosal tissues. In the thymus,…”
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Localization and intracellular transport of MHC class II molecules in bone marrow-derived dendritic cells by Pierre, P, Turley, S J, Meltzer, J, Mirza, A, Steinman, R, Mellman, I

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Molecular cloning and sequence analysis of U3 snoRNA-associated mouse fibrillarin by Turley, S J, Tan, E M, Pollard, K M

“…We have isolated and determined the sequence of a 1.1-kb cDNA from a murine WEHI-3 macrophage library which encodes the highly conserved, nucleolar protein,…”
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Fibrillarin and Other snoRNP Proteins Are Targets of Autoantibodies in Xenobiotic-Induced Autoimmunity by Yang, Jian-Ming, Baserga, Susan J., Turley, Shannon J., Pollard, K.Michael

“…Exposure of SJL/J mice to mercury induces an anti-nucleolar autoantibody response. The predominant target is fibrillarin, a 34-kDa component of the small…”
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AIRE in the thymus and beyond by Gardner, James M, Fletcher, Anne L, Anderson, Mark S, Turley, Shannon J

“…The maintenance of immunologic self-tolerance requires the coordination of multiple complementary systems. Studies of the Autoimmune Regulator ( Aire ) gene…”
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Adverse immunological effects and autoimmunity induced by dental amalgam and alloy in mice by Hultman, P, Johansson, U, Turley, S J, Lindh, U, Eneström, S, Pollard, K M

“…Dental amalgam fillings are the most important source of mercury exposure in the general population, but their potential to cause systemic health consequences…”
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TGF-β signalling attenuates tumour response to PD-L1 checkpoint blockade by contributing to retention of T cells in the peritumoural stroma by Mariathasan, S., Turley, S.J., Nickles, D., Castiglioni, A., Yuen, K., Wang, Y., Edward E, K., Koeppen, H., Astarita, J.L., Cubas, R., Jhunjhunwala, S., Yang, Y., Şenbabaoğlu, Y., van der Heijden, M., Loriot, Y., Mellman, I., Chen, D., Hegde, P., Bourgon, R., Powles, T.

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Testosterone is an endogenous regulator of BAFF and splenic B cell number by Wilhelmson, Anna S K, Lantero Rodriguez, Marta, Stubelius, Alexandra, Fogelstrand, Per, Johansson, Inger, Buechler, M. B., Lianoglou, S., Kapoor, V. N., Johansson, Maria E, Fagman, Johan Bourghardt, Duhlin, A., Tripathi, P., Camponeschi, Alessandro, Porse, B. T., Rolink, A. G., Nissbrandt, Hans, Turley, S. J., Carlsten, Hans, Mårtensson, Inga-Lill, Karlsson, M. C. I., Tivesten, Åsa

“…Testosterone deficiency in men is associated with increased risk for autoimmunity and increased B cell numbers through unknown mechanisms. Here we show that…”
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Unconventional antigen-presenting cells in the induction of peripheral CD8 super(+) T cell tolerance by Reynoso, ED, Turley, S J

“…Bone marrow-derived APCs are considered the predominant cell type involved in the induction and maintenance of T cell tolerance in vivo. In the periphery,…”
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Genetic Susceptibility to Silver-Induced Anti-fibrillarin Autoantibodies in Mice by Hultman, Per, Ganowiak, Katarzyna, Turley, Shannon J., Pollard, K.Michael

“…Similar to mercuric chloride, silver nitrate has recently been shown to induce IgG autoantibodies targeting the nucleolar 34-kDa protein fibrillarin i SJL (H-2…”
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Antigen processing for amateurs and professionals by Mellman, Ira, Turley, Shannon J, Steinman, Ralph M

“…The initiation and propagation of immune responses is dependent on the ability of antigen-presenting cells (APCs) to convert proteins into peptides, to load…”
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