Search Results - "TURKER, M. S"

DNA repair modulates the vulnerability of the developing brain to alkylating agents by Kisby, G.E., Olivas, A., Park, T., Churchwell, M., Doerge, D., Samson, L.D., Gerson, S.L., Turker, M.S.

“…Neurons of the developing brain are especially vulnerable to environmental agents that damage DNA (i.e., genotoxicants), but the mechanism is poorly…”
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The primary function of a redundant Sp1 binding site in the mouse aprt gene promoter is to block epigenetic gene inactivation by Mummaneni, Padmaja, Yates, Phil, Simpson, James, Rose, Jennifer, Turker, Mitchell S.

“…The promoter region of the mouse adenine phosphoribosyltransferase (aprt) gene contains one nonconsensus Sp1 binding site at its 5′ end followed by three…”
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Role of nucleotide- and base-excision repair in genotoxin-induced neuronal cell death by Kisby, G.E, Lesselroth, H, Olivas, A, Samson, L, Gold, B, Tanaka, K, Turker, M.S

“…Base-excision (BER) and nucleotide-excision (NER) repair play pivotal roles in protecting the genomes of dividing cells from damage by endogenous and exogenous…”
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A novel signature mutation for oxidative damage resembles a mutational pattern found commonly in human cancers by TURKER, M. S, GAGE, B. M, ROSE, J. A, ELROY, D, PONOMAREVA, O. N, STAMBROOK, P. J, TISCHFIELD, J. A

“…To determine the types of mutations induced by oxidative damage, a kidney cell line with a heterozygous deficiency for the autosomal Aprt (adenine…”
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A cis-acting element accounts for a conserved methylation pattern upstream of the mouse adenine phosphoribosyltransferase gene by PADMAJA MUMMANENI, BISHOP, P. L, TURKER, M. S

“…A 2.1-kilobase pair region located just upstream of the mouse aprt (adenine phosphoribosyltransferase) gene has a methylation pattern that is conserved in…”
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Fully expanded FMR1 CGG repeats exhibit a length- and differentiation-dependent instability in cell hybrids that is independent of DNA methylation by BURMAN, R. W, POPOVICH, B. W, JACKY, P. B, TURKER, M. S

“…The fragile X syndrome is characterized at the molecular level by expansion and methylation of a CGG trinucleotide repeat located within the FMR1 locus. The…”
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Genetic alterations distinguish different types of ovarian tumors by Pieretti, M, Cavalieri, C, Conway, P S, Gallion, H H, Powell, D E, Turker, M S

“…Seventy-four sporadic ovarian tumors were studied for loss of heterozygosity (LOH) and microsatellite instability (MI) with 20 polymorphic markers on…”
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Biallelic methylation and silencing of mouse Aprt in normal kidney cells by ROSE, J. A, YATES, P. A, SIMPSON, J, TISCHFIELD, J. A, STAMBROOK, P. J, TURKER, M. S

“…Heritable gene silencing is an important mechanism of tumor suppressor gene inactivation in a variety of human cancers. In the present study, we show that…”
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Solid tissues removed from Atm homozygous deficient mice do not exhibit a mutator phenotype for second-step autosomal mutations by TURKER, M. S, GAGE, B. M, ROSE, J. A, PONOMAREVA, O. N, TISCHFIELD, J. A, STAMBROOK, P. J, BARLOW, C, WYNSHAW-BORIS, A

“…The presence of increased frequencies of blood-derived and solid tumors in ataxia-telangiectasia (A-T) patients, coupled with a role for the ATM (A-T mutation)…”
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Hypomethylation of an Expanded FMR1 Allele Is Not Associated with a Global DNA Methylation Defect by Burman, Robert W., Yates, Phillip A., Green, Lindsay D., Jacky, Peter B., Turker, Mitchell S., Popovich, Bradley W.

“…The vast majority of fragile-X full mutations are heavily methylated throughout the expanded CGG repeat and the surrounding CpG island. Hypermethylation…”
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Mutation, ageing, and ovarian cancer by Pieretti, M, Turker, M S

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Molecular genetic changes in human epithelial ovarian malignancies by Gallion, H H, Powell, D E, Morrow, J K, Pieretti, M, Case, E, Turker, M S, DePriest, P D, Hunter, J E, van Nagell, Jr, J R

“…The frequent finding of loss of heterozygosity (LOH) for a specific chromosomal marker in tumor DNA compared to normal DNA suggests the presence of a closely…”
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A partial methylation profile for a CpG site is stably maintained in mammalian tissues and cultured cell lines by Turker, M S, Swisshelm, K, Smith, A C, Martin, G M

“…We wished to determine if a partial methylation profile for a specific CpG site was stably maintained in both mammalian tissues and cultured cell lines. To…”
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Genetic alterations on chromosome 17 distinguish different types of epithelial ovarian tumors by Pieretti, Maura, Powell, Deborah E, Gallion, Holly H, Case, Elizabeth A, Conway, Pamela S, Turker, Mitchell S

“…Epithelial tumors of the ovary are the most common ovarian tumors of adult women. They exist in several different histological patterns and exhibit varying…”
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The establishment and maintenance of DNA methylation patterns in mouse somatic cells by Turker, Mitchell S.

“…Somatic cell DNA methylation patterns in mammals are established during embryonic development and are then maintained somewhat faithfully for the remainder of…”
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Hypermethylation at a chromosome 17 “Hot spot” is a common event in ovarian cancer by Pieretti, Maura, Powell, Deborah E, Gallion, Holly H, Conway, Pamela S, Case, Elizabeth A, Turker, Mitchell S

“…Alterations of normal DNA methylation patterns have been reported in various types of human tumors. These alterations are represented by genome wide…”
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Podospora anserina does not senesce when serially passaged in liquid culture by Turker, M.S, Cummings, D.J

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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A novel family of mitochondrial plasmids associated with longevity mutants of Podospora anserina by Turker, M.S., Domenico, J.M., Cummings, D.J.

“…We have identified a novel family of plasmids, each containing very short monomeric units, in Podospora anserina longevity mutants. These plasmids, termed…”
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A Podospora anserina longevity mutant with a temperature-sensitive phenotype for senescence by TURKER, M. S, NELSON, J. G, CUMMINGS, D. J

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Tandem B1 Elements Located in a Mouse Methylation Center Provide a Target for de Novo DNA Methylation by Yates, P A, Burman, R W, Mummaneni, P, Krussel, S, Turker, M S

“…A cis-acting methylation center that signals de novo DNA methylation is located upstream of the mouse Aprt gene. In the current study, two approaches were…”
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