Search Results - "TURETSKAYA, R. L"
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Susceptibility locus for IgA deficiency and common variable immunodeficiency in the HLA-DR3, -B8, -A1 haplotypes
Published in Molecular medicine (Cambridge, Mass.) (01-02-1998)“…A common genetic basis for IgA deficiency (IgAD) and common variable immunodeficiency (CVID) is suggested by their occurrence in members of the same family and…”
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Loss of HLA haplotype and B locus down-regulation in melanoma cell lines
Published in The Journal of immunology (1950) (01-08-1994)“…The expression of HLA class I molecules on tumor cells is vital for CD8+T cell recognition of tumor Ags. Loss of HLA class I Ag expression as a result of…”
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Cloning and Expression Analysis of the Murine Lymphotoxin β Gene
Published in Proceedings of the National Academy of Sciences - PNAS (31-01-1995)“…Tumor necrosis factor α (TNF-α) and soluble lymphotoxin (LT) (also called LT-α or TNF-β) are cytokines with similar biological activities that are encoded by…”
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Abnormal Development of Secondary Lymphoid Tissues in Lymphotoxin β -deficient Mice
Published in Proceedings of the National Academy of Sciences - PNAS (19-08-1997)“…The tumor necrosis factor (TNF) family cytokines lymphotoxin (LT) α and LTβ form heterotrimers that are expressed on the surface of activated lymphocytes and…”
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Similarities and Differences Between Human and Murine TNF Promoters in Their Response to Lipopolysaccharide
Published in The Journal of immunology (1950) (01-04-1999)“…Transcription of the TNF gene is rapidly and transiently induced by LPS in cells of monocyte/macrophage lineage. Previous data suggested that multiple…”
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DNA sequence polymorphism at the human tumor necrosis factor (TNF) locus : numerous TNF/lymphotoxin alleles tagged by two closely linked microsatellites in the upstream region of the lymphotoxin (TNF-β) gene
Published in The Journal of immunology (1950) (01-08-1991)“…TNF-alpha and lymphotoxin (LT, TNF-beta) genes are tandemly arranged and map within the MHC centromeric to HLA-B and telomeric to the class III genes. Both…”
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Redundancy in Tumor Necrosis Factor (TNF) and Lymphotoxin (LT) Signaling In Vivo: Mice with Inactivation of the Entire TNF/LT Locus versus Single-Knockout Mice
Published in Molecular and Cellular Biology (01-12-2002)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Changes in the hemopoietic system of mice deficient for tumor necrosis factor or lymphotoxin-alpha
Published in Bulletin of experimental biology and medicine (01-07-2000)“…Hemopoietic and stromal precursor cells were studied in mice deficient for tumor necrosis factor or lymphotoxin-alpha. In normal hemopoiesis the main…”
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Comparative Characterization of Lymphotoxin Transcripts from Human B- and T-Cell Lines, Peripheral Lymphocytes, and Normal Tissues
Published in Molecular biology (New York) (01-01-2001)“…Membrane lymphotoxin (LT) is a heterotrimer LTα^sub 1^β^sub 2^, and its production depends on two genes. Northern blotting was employed in studying their…”
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Conserved kappa B element located downstream of the tumor necrosis factor alpha gene: distinct NF-kappa B binding pattern and enhancer activity in LPS activated murine macrophages
Published in Oncogene (06-07-1995)“…Transcriptional activation of various genes by lipopolysaccharide (LPS) is known to be mediated, at least in part, by the NF-kappa B/Rel family of…”
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An STS in the human TNF locus located at 6p21.3
Published in Nucleic acids research (11-09-1991)“…Human genes encoding tumor necrosis factor (TNF- alpha ) and lymphotoxin (TNF- beta ) are tandemly arranged and located at 6p21.3. Their precise position…”
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An autocrine growth factor constitutively produced by a human lymphoblastoid B-cell line is serologically related to lymphotoxin (TNF-beta)
Published in Molecular immunology (01-03-1989)“…Conditioned medium of a human lymphoblastoid B-cell line RPMI-6410t contains a factor sufficient for maintainance and growth of these cells. At the same time…”
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Functional analysis of the lymphotoxin-beta promoter. Sequence requirements for PMA activation
Published in The Journal of immunology (1950) (01-04-1996)“…Membrane lymphotoxin (LT) complex is a trimer composed of two subunits , LT-alpha and LT-beta of which the latter is a 33-kDa transmembrane protein. The…”
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Genetic polymorphism of the human tumor necrosis factor region in insulin-dependent diabetes mellitus linkage disequilibrium of TNFab microsatellite alleles with HLA haplotypes
Published in Human immunology (01-10-1995)“…The TNF region within the MHC includes a number of immunologically important genes. Microsatellites TNFa and TNFb adjacent to TNF exhibit extensive…”
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Genomic structure, induction, and production of TNF-beta
Published in Immunology series (1992)Get more information
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Cloning and characterization of the rabbit lymphotoxin (TNF-β) gene and its tight linkage to the gene coding for tumor necrosis factor
Published in Nucleic acids research (11-04-1988)“…A rabbit genomic library was screened for the lymphotoxin (LT, TNF- beta ) gene with subcloned fragments of human and mouse LT genes. One positive out of 10…”
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Highly informative typing of the human TNF locus using six adjacent polymorphic markers
Published in Genomics (San Diego, Calif.) (01-04-1993)“…The human tumor necrosis factor locus (TNF locus) is located within the major histocompatibility complex between the class III genes and HLA-B. We recently…”
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