Search Results - "TURBACHOVA, Ivana"

Mastermind mediates chromatin-specific transcription and turnover of the Notch enhancer complex by Fryer, Christy J, Lamar, Elise, Turbachova, Ivana, Kintner, Chris, Jones, Katherine A

“…Signaling through the Notch pathway activates the proteolytic release of the Notch intracellular domain (ICD), a dedicated transcriptional coactivator of CSL…”
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Epigenetic quantification of tumor-infiltrating T-lymphocytes by Sehouli, Jalid, Loddenkemper, Christoph, Cornu, Tatjana, Schwachula, Tim, Hoffmüller, Ulrich, Grützkau, Andreas, Lohneis, Philipp, Dickhaus, Thorsten, Gröne, Jörn, Kruschewski, Martin, Mustea, Alexander, Turbachova, Ivana, Baron, Udo, Olek, Sven

“…The immune system plays a pivotal role in tumor establishment. However, the role of T-lymphocytes within the tumor microenvironment as major cellular component…”
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Inhibitors of the Nonmevalonate Pathway of Isoprenoid Biosynthesis as Antimalarial Drugs by Jomaa, Hassan, Wiesner, Jochen, Sanderbrand, Silke, Altincicek, Boran, Weidemeyer, Claus, Hintz, Martin, Türbachova, Ivana, Eberl, Matthias, Zeidler, Johannes, Lichtenthaler, Hartmut K., Soldati, Dominique, Beck, Ewald

“…A mevalonate-independent pathway of isoprenoid biosynthesis present in Plasmodium falciparum was shown to represent an effective target for chemotherapy of…”
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The Thioredoxin System of the Malaria Parasite Plasmodium falciparum by Kanzok, Stefan M., Schirmer, R. Heiner, Türbachova, Ivana, Iozef, Rimma, Becker, Katja

“…In most living cells, redox homeostasis is based both on the glutathione and the thioredoxin system. In the malaria parasite Plasmodium falciparum…”
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Quantitative DNA Methylation Analysis of FOXP3 as a New Method for Counting Regulatory T Cells in Peripheral Blood and Solid Tissue by WIECZOREK, Georg, ASEMISSEN, Anne, HAMANN, Alf, LODDENKEMPER, Christoph, STEIN, Harald, DIETER VOLK, Hans, HOFFMÜLLER, Ulrich, GRÜTZKAU, Andreas, MUSTEA, Alexander, HUEHN, Jochen, SCHEIBENBOGEN, Carmen, OLEK, Sven, MODEL, Fabian, TURBACHOVA, Ivana, FLOES, Stefan, LIEBENBERG, Volker, BARON, Udo, STAUCH, Diana, KOTSCH, Katja, PRATSCHKE, Johann

“…Regulatory T-cells (Treg) have been the focus of immunologic research due to their role in establishing tolerance for harmless antigens versus allowing immune…”
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DNA Methylation Analysis as a Tool for Cell Typing by Baron, Udo, Turbachova, Ivana, Hellwag, Alexander, Eckhardt, Florian, Berlin, Kurt, Hoffmüller, Ulrich, Gardina, Paul, Olek, Sven

“…Cell therapeutic approaches currently lack definitive quality control measures which guarantee safety in clinical applications and create consistent standards…”
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Wild-type FOXP3 is selectively active in CD4+CD25(hi) regulatory T cells of healthy female carriers of different FOXP3 mutations by Di Nunzio, Sara, Cecconi, Massimiliano, Passerini, Laura, McMurchy, Alicia N, Baron, Udo, Turbachova, Ivana, Vignola, Silvia, Valencic, Erica, Tommasini, Alberto, Junker, Anne, Cazzola, Giantonio, Olek, Sven, Levings, Megan K, Perroni, Lucia, Roncarolo, Maria Grazia, Bacchetta, Rosa

“…Forkhead box P3 (FOXP3) is constitutively expressed by CD4(+)CD25(hi) regulatory T cells (nTregs). Mutations of FOXP3 cause a severe autoimmune syndrome known…”
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Vaccine candidate MSP-1 from Plasmodium falciparum: A redesigned 4917 bp polynucleotide enables synthesis and isolation of full-length protein from Escherichia coli and mammalian cells by Pan, Weiqing, Ravot, Elisabetta, Tolle, Ralf, Frank, Rainer, Mosbach, Raphael, Türbachova, Ivana, Bujard, Hermann

“…The Plasmodium falciparum malaria parasite is the causative agent of malaria tropica. Merozoites, one of the extracellular developmental stages of this…”
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DNA demethylation in the human FOXP3 locus discriminates regulatory T cells from activated FOXP3⁺ conventional T cells by Baron, Udo, Floess, Stefan, Wieczorek, Georg, Baumann, Katrin, Grützkau, Andreas, Dong, Jun, Thiel, Andreas, Boeld, Tina J, Hoffmann, Petra, Edinger, Matthias, Türbachova, Ivana, Hamann, Alf, Olek, Sven, Huehn, Jochen

“…The transcription factor FOXP3 is critical for development and function of regulatory T cells (Treg). Their number and functioning appears to be crucial in the…”
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Wild-type FOXP3 is selectively active in CD4+CD25hi regulatory T cells of healthy female carriers of different FOXP3 mutations by Di Nunzio, Sara, Cecconi, Massimiliano, Passerini, Laura, McMurchy, Alicia N., Baron, Udo, Turbachova, Ivana, Vignola, Silvia, Valencic, Erica, Tommasini, Alberto, Junker, Anne, Cazzola, Giantonio, Olek, Sven, Levings, Megan K., Perroni, Lucia, Roncarolo, Maria Grazia, Bacchetta, Rosa

“…Forkhead box P3 (FOXP3) is constitutively expressed by CD4+CD25hi regulatory T cells (nTregs). Mutations of FOXP3 cause a severe autoimmune syndrome known as…”
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Germline mutations of BRCA1 gene exon 11 are not associated with platinum response neither with survival advantage in patients with primary ovarian cancer: understanding the clinical importance of one of the biggest human exons. A study of the Tumor Bank Ovarian Cancer (TOC) Consortium by Dimitrova, Desislava, Ruscito, Ilary, Olek, Sven, Richter, Rolf, Hellwag, Alexander, Türbachova, Ivana, Woopen, Hannah, Baron, Udo, Braicu, Elena Ioana, Sehouli, Jalid

“…Germline mutations in BRCA1 gene have been reported in up to 20 % of epithelial ovarian cancer (EOC) patients. Distinct clinical characteristics have been…”
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The cellular ratio of immune tolerance (immunoCRIT) is a definite marker for aggressiveness of solid tumors and may explain tumor dissemination patterns by Türbachova, Ivana, Schwachula, Tim, Vasconcelos, Ines, Mustea, Alexander, Baldinger, Tina, Jones, Katherine A, Bujard, Hermann, Olek, Alexander, Olek, Klaus, Gellhaus, Katharina, Braicu, Ioana, Könsgen, Dominique, Fryer, Christy, Ravot, Elisabetta, Hellwag, Alexander, Westerfeld, Nicole, Gruss, Oliver J, Meissner, Markus, Hasan, Mazahir T, Weber, Michael, Hoffmüller, Ulrich, Zimmermann, Sven, Loddenkemper, Christoph, Mahner, Sven, Babel, Nina, Berns, Els, Adams, Richard, Zeilinger, Robert, Baron, Udo, Vergote, Ignace, Maughan, Tim, Marme, Frederik, Dickhaus, Thorsten, Sehouli, Jalid, Olek, Sven

“…The adaptive immune system is involved in tumor establishment and aggressiveness. Tumors of the ovaries, an immune-privileged organ, spread via transceolomic…”
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