Search Results - "TUOMILEHTO, Jaakko"

The Emerging Global Epidemic of Type 1 Diabetes by Tuomilehto, Jaakko

“…Type 1 diabetes mellitus (T1D) can occur at any age, with a peak in incidence around puberty. Classification between T1D and type 2 diabetes becomes more…”
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Nonpharmacologic Therapy and Exercise in the Prevention of Type 2 Diabetes by Tuomilehto, Jaakko

“…OBJECTIVE: To review the current knowledge about nonpharmacologic approaches in the prevention and early treatment of type 2 diabetes. RESEARCH DESIGN AND…”
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Functional Foods and Lifestyle Approaches for Diabetes Prevention and Management by Alkhatib, Ahmad, Tsang, Catherine, Tiss, Ali, Bahorun, Theeshan, Arefanian, Hossein, Barake, Roula, Khadir, Abdelkrim, Tuomilehto, Jaakko

“…Functional foods contain biologically active ingredients associated with physiological health benefits for preventing and managing chronic diseases, such as…”
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Time trends in the incidence of type 1 diabetes in Finnish children: a cohort study by Harjutsalo, Valma, PhD, Sjöberg, Lena, MD, Tuomilehto, Jaakko, Prof

“…Summary Background Finland has the highest incidence of type 1 diabetes worldwide, reaching 40 per 100 000 people per year in the 1990s. Our aim was to assess…”
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Lifestyle Intervention with Weight Reduction: First-line Treatment in Mild Obstructive Sleep Apnea by Tuomilehto, Henri P. I, Seppa, Juha M, Partinen, Markku M, Peltonen, Markku, Gylling, Helena, Tuomilehto, Jaakko O. I, Vanninen, Esko J, Kokkarinen, Jouko, Sahlman, Johanna K, Martikainen, Tarja, Soini, Erkki J. O, Randell, Jukka, Tukiainen, Hannu, Uusitupa, Matti, on behalf of Kuopio Sleep Apnea Group

“…Obesity is the most important risk factor for obstructive sleep apnea (OSA). However, although included in clinical guidelines, no randomized controlled…”
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Effects of coffee consumption on subclinical inflammation and other risk factors for type 2 diabetes: a clinical trial by Kempf, Kerstin, Herder, Christian, Erlund, Iris, Kolb, Hubert, Martin, Stephan, Carstensen, Maren, Koenig, Wolfgang, Sundvall, Jouko, Bidel, Siamak, Kuha, Suvi, Jaakko, Tuomilehto

“…BACKGROUND: Coffee consumption is associated with a decreased risk of type 2 diabetes. Suggested mechanisms underlying the association have included…”
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Olive Oil Nutraceuticals in the Prevention and Management of Diabetes: From Molecules to Lifestyle by Alkhatib, Ahmad, Tsang, Catherine, Tuomilehto, Jaakko

“…Lifestyle is the primary prevention of diabetes, especially type-2 diabetes (T2D). Nutritional intake of olive oil (OO), the key Mediterranean diet component…”
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Age-Related Clonal Hematopoiesis Associated with Adverse Outcomes by Jaiswal, Siddhartha, Fontanillas, Pierre, Flannick, Jason, Manning, Alisa, Grauman, Peter V, Mar, Brenton G, Lindsley, R. Coleman, Mermel, Craig H, Burtt, Noel, Chavez, Alejandro, Higgins, John M, Moltchanov, Vladislav, Kuo, Frank C, Kluk, Michael J, Henderson, Brian, Kinnunen, Leena, Koistinen, Heikki A, Ladenvall, Claes, Getz, Gad, Correa, Adolfo, Banahan, Benjamin F, Gabriel, Stacey, Kathiresan, Sekar, Stringham, Heather M, McCarthy, Mark I, Boehnke, Michael, Tuomilehto, Jaakko, Haiman, Christopher, Groop, Leif, Atzmon, Gil, Wilson, James G, Neuberg, Donna, Altshuler, David, Ebert, Benjamin L

“…About 10% of people older than 70 years of age carry one or more mutations in their hematopoietic cells, and these persons have a higher relative risk of a…”
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Remission of T2DM requires early diagnosis and substantial weight reduction by Bergman, Michael, Buysschaert, Martin, Medina, José Luiz, Tuomilehto, Jaakko

“…Remission of type 2 diabetes mellitus is highly desirable and potentially reduces risks of complications. Improving the probability of remission requires early…”
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ANGPTL8 (betatrophin) role in diabetes and metabolic diseases by Abu‐Farha, Mohamed, Abubaker, Jehad, Tuomilehto, Jaakko

“…Summary Diabetes is a major disease worldwide that is reaching epidemic levels. Its increased prevalence as well as its association with a high number of…”
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Incident dementia and blood pressure lowering in the Hypertension in the Very Elderly Trial cognitive function assessment (HYVET-COG): a double-blind, placebo controlled trial by Peters, Ruth, PhD, Beckett, Nigel, MBchB, Forette, Francoise, MD, Tuomilehto, Jaakko, MD, Clarke, Robert, FRCP, Ritchie, Craig, MRCPsych, Waldman, Adam, PhD, Walton, Ivan, FRCP, Poulter, Ruth, BSc, Ma, Shuping, MD, Comsa, Marius, MD, Burch, Lisa, BSc, Fletcher, Astrid, PhD, Bulpitt, Christopher, MD

“…Summary Background Observational epidemiological studies have shown a positive association between hypertension and risk of incident dementia; however, the…”
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Twelve-year trends in the prevalence and risk factors of diabetes and prediabetes in Turkish adults by Satman, Ilhan, Omer, Beyhan, Tutuncu, Yildiz, Kalaca, Sibel, Gedik, Selda, Dinccag, Nevin, Karsidag, Kubilay, Genc, Sema, Telci, Aysegul, Canbaz, Bulent, Turker, Fulya, Yilmaz, Temel, Cakir, Bekir, Tuomilehto, Jaakko

“…There is concern about an emerging diabetes epidemic in Turkey. We aimed to determine the prevalence of diagnosed and undiagnosed diabetes, prediabetes and…”
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Glucose Control and Vascular Outcomes in Type 2 Diabetes: Is the Picture Clear? by Giorgino, Francesco, Home, Philip D, Tuomilehto, Jaakko

“…The overall impact of glucose lowering on vascular complications and major clinical outcomes, including mortality, in type 2 diabetes is still an open issue…”
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Cardiovascular health metrics from mid- to late-life and risk of dementia: A population-based cohort study in Finland by Liang, Yajun, Ngandu, Tiia, Laatikainen, Tiina, Soininen, Hilkka, Tuomilehto, Jaakko, Kivipelto, Miia, Qiu, Chengxuan

“…Very few studies have explored the patterns of cardiovascular health (CVH) metrics in midlife and late life in relation to risk of dementia. We examined the…”
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Multidomain lifestyle intervention benefits a large elderly population at risk for cognitive decline and dementia regardless of baseline characteristics: The FINGER trial by Rosenberg, Anna, Ngandu, Tiia, Rusanen, Minna, Antikainen, Riitta, Bäckman, Lars, Havulinna, Satu, Hänninen, Tuomo, Laatikainen, Tiina, Lehtisalo, Jenni, Levälahti, Esko, Lindström, Jaana, Paajanen, Teemu, Peltonen, Markku, Soininen, Hilkka, Stigsdotter-Neely, Anna, Strandberg, Timo, Tuomilehto, Jaakko, Solomon, Alina, Kivipelto, Miia

“…The 2-year Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) multidomain lifestyle intervention trial (NCT01041989)…”
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Dietary factors and low-grade inflammation in relation to overweight and obesity by Calder, Philip C., Ahluwalia, Namanjeet, Brouns, Fred, Buetler, Timo, Clement, Karine, Cunningham, Karen, Esposito, Katherine, Jönsson, Lena S., Kolb, Hubert, Lansink, Mirian, Marcos, Ascension, Margioris, Andrew, Matusheski, Nathan, Nordmann, Herve, O'Brien, John, Pugliese, Giuseppe, Rizkalla, Salwa, Schalkwijk, Casper, Tuomilehto, Jaakko, Wärnberg, Julia, Watzl, Bernhard, Winklhofer-Roob, Brigitte M.

“…Low-grade inflammation is a characteristic of the obese state, and adipose tissue releases many inflammatory mediators. The source of these mediators within…”
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The prevalence of obesity and overweight, associated demographic and lifestyle factors, and health status in the adult population of Jeddah, Saudi Arabia by Al-Raddadi, Rajaa, Bahijri, Suhad M., Jambi, Hanan A., Ferns, Gordon, Tuomilehto, Jaakko

“…Background: Obesity is a risk factor for many chronic diseases, and its prevalence and trends vary among populations. Saudi Arabia shows a greater rise in…”
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Type 2 Diabetes and the Risk of Parkinson's Disease by Hu, Gang, Jousilahti, Pekka, Bidel, Siamak, Antikainen, Riitta, Tuomilehto, Jaakko

“…OBJECTIVE:--To evaluate whether type 2 diabetes at baseline is a risk factor for Parkinson's disease. RESEARCH DESIGN AND METHODS--We prospectively followed…”
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Total and High-Density Lipoprotein Cholesterol and Stroke Risk by YURONG ZHANG, TUOMILEHTO, Jaakko, JOUSILAHTI, Pekka, YUJIE WANG, ANTIKAINEN, Riitta, GANG HU

“…The association of total and high-density lipoprotein (HDL) cholesterol with stroke risk is unclear, especially regarding hemorrhagic stroke. We prospectively…”
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Age at initiation and frequency of screening to detect type 2 diabetes: a cost-effectiveness analysis by Kahn, Richard, Dr, Alperin, Peter, MD, Eddy, David, MD, Borch-Johnsen, Knut, MD, Buse, John, MD, Feigelman, Justin, Gregg, Edward, PhD, Holman, Rury R, MD, Kirkman, M Sue, MD, Stern, Michael, MD, Tuomilehto, Jaakko, MD, Wareham, Nick J, Prof

“…Summary Background No clinical trials have assessed the effects or cost-effectiveness of sequential screening strategies to detect new cases of type 2…”
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