Search Results - "TUBIANA MATHIEU, N"

Molecular subtypes of metastatic colorectal cancer are associated with patient response to irinotecan-based therapies by Del Rio, M, Mollevi, C, Bibeau, F, Vie, N, Selves, J, Emile, J.-F, Roger, P, Gongora, C, Robert, J, Tubiana-Mathieu, N, Ychou, M, Martineau, P

“…Abstract Background Currently, metastatic colorectal cancer is treated as a homogeneous disease and only RAS mutational status has been approved as a negative…”
Get full text

Chemotherapy Response Evaluation in Metastatic Colorectal Cancer with FDG PET/CT and CT Scans by J. MONTEIL, N. MAHMOUDI, S. LEOBON, P.Y. ROUDAUT, A. EL BADAOUI, S. VERBEKE, L. VENAT-BOUVET, J. MARTIN, V. LE BRUN-LY, S. LAVAU-DENES, A. MAUBON, P. BOUILLET, M. POUQUET, J.C. VANDROUX, N. TUBIANA-MATHIEU

“…Background: [18F]-fluorodeoxyglucose with positron-emission tomography (PET) and computed tomography (CT) scans were used to assess morphological and metabolic…”
Get full text

Concomitant intensive chemoradiotherapy induction in non-metastatic inflammatory breast cancer: long-term follow-up by GENET, D, LEJEUNE, C, LEBRUN-LY, V, JUIN, P, PIANA, L, TUBIANA-MATHIEU, N, BONNIER, P, AUBARD, Y, VENAT-BOUVET, L, ADJADJ, D. J, MARTIN, J, LABOUREY, J. L, BENYOUB, A, CLAVERE, P

“…The aim of this study was to evaluate with a long follow-up the efficacy of concomitant chemoradiotherapy in non-metastatic inflammatory breast cancer (IBC)…”
Get full text

Predictors of women’s attendance in a home-based adapted physical activity program during localized breast cancer treatment by Deveautour-Roy, E., Tubiana-Mathieu, N., Léobon, S., Vincent, F., Venat, L., Sombardier, T., Deluche, E., Mandigout, S.

“…Purpose The objective of this study is to evaluate predictors for attendance in a home-based adapted physical activity (APA) program for women with breast…”
Get full text

Multicentric neoadjuvant phase II study of panitumumab combined with an anthracycline/taxane-based chemotherapy in operable triple-negative breast cancer: identification of biologically defined signatures predicting treatment impact by Nabholtz, J.M., Abrial, C., Mouret-Reynier, M.A., Dauplat, M.M., Weber, B., Gligorov, J., Forest, A.M., Tredan, O., Vanlemmens, L., Petit, T., Guiu, S., Van Praagh, I., Jouannaud, C., Dubray-Longeras, P., Tubiana-Mathieu, N., Benmammar, K.E., Kullab, S., Bahadoor, M.R.K., Radosevic-Robin, N., Kwiatkowski, F., Desrichard, A., Cayre, A., Uhrhammer, N., Chalabi, N., Chollet, P., Penault-Llorca, F.

“…Triple-negative breast cancer (TNBC) is a heterogeneous group of tumors for some of which the epithelial growth factor receptor (EGFR) pathway may play an…”
Get full text

Comprehensive geriatric assessment predicts tolerance to chemotherapy and survival in elderly patients with advanced ovarian carcinoma: a GINECO study by Freyer, G., Geay, J.-F., Touzet, S., Provencal, J., Weber, B., Jacquin, J.-P., Ganem, G., Tubiana-Mathieu, N., Gisserot, O., Pujade-Lauraine, E.

“…Background: Data from prospective clinical trials are needed to better define standards of care in elderly patients with advanced ovarian carcinoma and to…”
Get full text

Prophylaxis of catheter-related deep vein thrombosis in cancer patients with low-dose warfarin, low molecular weight heparin, or control: a randomized, controlled, phase III study by Lavau-Denes, Sandrine, Lacroix, P., Maubon, A., Preux, P. M., Genet, D., Vénat-Bouvet, L., Labourey, J. L., Martin, J., Slaouti, P., Tubiana-Mathieu, N.

“…Purpose Whether an anticoagulant prophylaxis is needed for patients with cancer with a central venous catheter is a highly controversial subject. We designed a…”
Get full text

Thrombotic microangiopathy and digital necrosis: two unrecognized toxicities of gemcitabine by Vénat-Bouvet, L, Ly, K, Szelag, J. C, Martin, J, Labourey, J. L, Genet, D, Tubiana-Mathieu, N

“…We report one new case of hemolytic–uremic syndrome (HUS) and one case of digital necrosis after treatment with gemcitabine (Gemzar). Case 1, a 34-year-old…”
Get full text

Long-Term Survival in Adult Neuroblastoma with Multiple Recurrences by Vénat-Bouvet, L., Le Brun-Ly, V., Martin, J., Gasnier, O., Falkowsky, S., Tubiana-Mathieu, N.

“…Neuroblastoma (NB) rarely occurs in adults, and less than 10% of the cases occur in patients older than 10 years. Currently, there are no standard treatment…”
Get full text

Effects of a home-based walking training program on cardiorespiratory fitness in breast cancer patients receiving adjuvant chemotherapy: a pilot study by Vincent, F, Labourey, J L, Leobon, S, Antonini, M T, Lavau-Denes, S, Tubiana-Mathieu, N

“…Breast cancer treatment is associated with a decline in measured cardiorespiratory fitness and increased fatigue. There is accumulating evidence that exercise…”
Get more information

1746 Oral anticancer agents: Necessity of personalized monitoring of patients by Falkowski, S, Raffy, P, Lagarde, A, Le Brun-ly, V, Venat-bouvet, L, Thuillier, F, Tubiana-mathieu, N

Get full text

Epirubicin dose and sequential hormonal therapy—Mature results of the HMFEC randomised phase III trial in premenopausal patients with node positive early breast cancer by Coombes, R.C, Kilburn, L.S, Tubiana-Mathieu, N, Olmos, T, Van Bochove, A, Perez-Lopez, F.R, Palmieri, C, Stebbing, J, Bliss, J.M

“…Abstract Background The hormonal manipulation 5-Fluoro-uracil Epirubicin Cyclophosphamide (HMFEC) trial was developed at a time of uncertainty around the dose…”
Get full text

Docetaxel plus 5-fluorouracil in locally recurrent and/or metastatic squamous cell carcinoma of the head and neck: a phase II multicenter study by Genet, Dominique, Cupissol, D, Calais, G, Bontemps, P, Bourgeois, H, Dutin, J P, Philippi, M H, Bendahmane, B, Mallard-Carre, M, Tubiana-Mathieu, N

“…This phase II study evaluated docetaxel-5-fluorouracil (5-FU) in locally recurrent and/or metastatic squamous cell carcinoma of the head and neck (SCCHN)…”
Get full text

Sensitive determination of vinorelbine and its metabolites in human serum using liquid chromatography-electrospray mass spectrometry by Ragot, S., Sauvage, F.L., Rousseau, A., Genet, D., Dupuy, J.L., Tubiana-Mathieu, N., Marquet, P.

“…A liquid chromatography-electrospray mass spectrometry method was developed for the quantitation of vinorelbine (VNB) and two metabolites, vinorelbine N-oxide…”
Get full text

1857 Final results of a phase II study evaluating oral vinorelbine as a single-agent as first-line chemotherapy for metastatic breast cancer patients with bone metastases (NorBreast-228 trial) by Steger, G.G, Dominguez, A, Dobrovolskaya, N, Giotta, F, Tubiana-Mathieu, N, Ardizzoia, A, Blasinska, M, Espinosa, E, Landreau, P, Villanova, G

Get full text

All-oral combination of oral vinorelbine and capecitabine as first-line chemotherapy in HER2-negative metastatic breast cancer: an International Phase II Trial by Tubiana-Mathieu, N, Bougnoux, P, Becquart, D, Chan, A, Conte, P-F, Majois, F, Espie, M, Morand, M, Vaissiere, N, Villanova, G

“…Background: This multicentre, international phase II trial evaluated the efficacy and safety profile of a first-line combination of oral vinorelbine plus…”
Get full text

Pharmacokinetics and exposure–effect relationships of capecitabine in elderly patients with breast or colorectal cancer by Daher Abdi, Z., Lavau-Denes, S., Prémaud, A., Urien, S., Sauvage, F. L., Martin, J., Leobon, S., Marquet, P., Tubiana-Mathieu, N., Rousseau, A.

“…Purpose The aims of the present study were (1) to investigate the impact of great age on pharmacokinetics of capecitabine and its metabolites and (2) to…”
Get full text

Expression Levels of Thymidylate Synthase, Thymidylate Phosphorylase and Dihydropyrimidine Dehydrogenase in Head and Neck Squamous Cell Carcinoma: Preliminary Study by Aubry, K., Labourey, J.L., Bessède, J.P., Tubiana-Mathieu, N., Rigaud, M.

“…Introduction Pharyngo-laryngeal tumors classified as T3-4, N0-3, M0, are conventionally treated by mutilating surgery (total (pharyngo)-laryngectomy)…”
Get full text

Pre-irradiation Chemotherapy for Newly Diagnosed High Grade Astrocytoma by TUBIANA MATHIEU, N, GENET, D, LABROUSSE, F, BOUILLET, P, LAVAU DENES, S, MARTIN, J, LABOUREY, J. L, VENAT, L, CLAVERE, P, MOREAU, J. J

“…The purpose of this work was to determine the response rate and toxicity of a combination of Carmustine and Cisplatin administered before radiation in patients…”
Get full text

232 Final Results of a Phase II Study of the Combination of Oral Vinorelbine (NVBo), Capecitabine (X) and Trastuzumab (H) in HER2-positive Metastatic Breast Cancer (MBC) by Petruzelka, L, Ganju, V, Conte, P.F, Tubiana-Mathieu, N, Majois, F, Espie, M, Llombart, A, Gil, M. Gil, Villanova, G, Chan, A

Get full text