Search Results - "TSUNO, N."

Cyclooxygenase-2 overexpression correlates with tumour recurrence, especially haematogenous metastasis, of colorectal cancer by TOMOZAWA, S, TSUNO, N. H, SUNAMI, E, HATANO, K, KITAYAMA, J, OSADA, T, SAITO, S, TSURUO, T, SHIBATA, Y, NAGAWA, H

“…Epidemiological studies have demonstrated that nonsteroidal anti-inflammatory drugs (NSAIDs), known to inhibit cyclooxygenase (COX), reduce the risk of…”
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Surgical stress response after colorectal resection: a comparison of robotic, laparoscopic, and open surgery by Shibata, J., Ishihara, S., Tada, N., Kawai, K., Tsuno, N. H., Yamaguchi, H., Sunami, E., Kitayama, J., Watanabe, T.

“…Background The perioperative immune status of colorectal robotic surgery (RS), laparoscopic surgery (LS), and open surgery (OS) patients has not been compared…”
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Recommendations of the ISBT Working Party on Granulocyte Immunobiology for leucocyte antibody screening in the investigation and prevention of antibody‐mediated transfusion‐related acute lung injury by Bierling, P., Bux, J., Curtis, B., Flesch, B., Fung, L., Lucas, G., Macek, M., Muniz‐Diaz, E., Porcelijn, L., Reil, A., Sachs, U., Schuller, R., Tsuno, N., Uhrynowska, M., Urbaniak, S., Valentin, N., Wikman, A., Zupanska, B.

“…Background  Transfusion‐related acute lung injury (TRALI) is currently one of the most common causes of transfusion‐related major morbidity and death. Among…”
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Regulation of the lysophosphatidylserine and sphingosine 1-phosphate levels in autologous whole blood by the pre-storage leukocyte reduction by Nagura, Y., Tsuno, N. H., Kano, K., Inoue, A., Aoki, J., Hirowatari, Y., Kaneko, M., Kurano, M., Matsuhashi, M., Ohkawa, R., Tozuka, M., Yatomi, Y., Okazaki, H.

“…SUMMARY Background and objectives The effect of leukoreduction and storage periods on the accumulation of bioactive lysophospholipids and substances in human…”
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Effect of Ruthenium on Creep Strength of Ni-Base Single-Crystal Superalloys at 750 °C and 750 MPa by Tsuno, N., Kakehi, K., Rae, C.M.F., Hashizume, R.

“…The effect of Ru on the creep behavior of two kinds of single-crystal Ni-base superalloys was studied at 750 °C and 750 MPa to discern the benefit of Ru as a…”
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Vaccines targeting tumour angiogenesis—a novel strategy for cancer immunotherapy by Okaji, Y., Tsuno, N.H., Saito, S., Yoneyama, S., Tanaka, M., Nagawa, H., Takahashi, K.

“…To review the concept of tumour angiogenesis and anti-angiogenic therapy, limitations of recently used anti-angiogenic therapeutics; provide an up-to-date…”
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Perinatal management of neonatal alloimmune thrombocytopenia associated with anti-group A antibody by Ueda, H., Sugiura, T., Katano, K., Matsuhashi, M., Kato, S., Ito, K., Nagasaki, R., Kato, T., Tsuno, N. H., Saitoh, S.

“…SUMMARY Objective To prevent neonatal alloimmune thrombocytopenia due to anti‐group A antibody perinatal management was performed. Background We previously…”
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Inhibition of haematogenous metastasis of colon cancer in mice by a selective COX-2 inhibitor, JTE-522 by TOMOZAWA, S, NAGAWA, H, TSURUO, T, SHIBATA, Y, MUTO, T, TSUNO, N, HATANO, K, OSADA, T, KITAYAMA, J, SUNAMI, E, NITA, M. E, ISHIHARA, S, YANO, H

“…It is proposed that non-steroidal anti-inflammatory drugs (NSAIDs) reduce colorectal tumorigenesis by inhibition of cyclooxygenase (COX). COX is a key enzyme…”
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5-Fluorouracil induces apoptosis in human colon cancer cell lines with modulation of Bcl-2 family proteins by NITA, M. E, NAGAWA, H, TOMINAGA, O, TSUNO, N, FUJII, S, SASAKI, S, FU, C.-G, TAKENOUE, T, TSURUO, T, MUTO, T

“…Recently, apoptosis has been implicated as one of the end points of cells exposed to chemotherapeutic agents. The p53 and Bcl-2 family of proteins are involved…”
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The suppressive effect of sphingosine 1-phosphate on monocyte-endothelium adhesion may be mediated by the rearrangement of the endothelial integrins alpha(5)beta(1) and alpha(v)beta(3) by Aoki, S, Yatomi, Y, Shimosawa, T, Yamashita, H, Kitayama, J, Tsuno, N H, Takahashi, K, Ozaki, Y

“…Sphingosine 1-phosphate (S1P), known to play important roles in vascular biology, is a bioactive lysophospholipid mediator that maintains endothelial integrity…”
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Epigallocatechin gallate, the main component of tea polyphenol, binds to CD4 and interferes with gp120 binding by Kawai, Kazushige, Tsuno, Nelson H, Kitayama, Joji, Okaji, Yurai, Yazawa, Kentaro, Asakage, Masahiro, Hori, Nobukazu, Watanabe, Toshiaki, Takahashi, Koki, Nagawa, Hirokazu

“…Epigallocatechin gallate (EGCG), the major component of tea polyphenol, has been reported to have various physiologic modulatory activities. Several reports…”
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Prognostic significance of glutamine synthetase expression in unifocal advanced hepatocellular carcinoma by OSADA, T, NAGASHIMA, I, TSUNO, N. H, KITAYAMA, J, NAGAWA, H

“…Glutamine synthetase (GS) catalyzes the synthesis of glutamine, a major energy source of cells, and is upregulated in a subset of human hepatocellular…”
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Quantification of minimal residual disease in patients with e1a2 BCR-ABL-positive acute lymphoblastic leukemia using a real-time RT-PCR assay by YOKOTA, H, TSUNO, N. H, NAKAHARA, K, TANAKA, Y, FUKUI, T, KITAMURA, K, HIRAI, H, OSUMI, K, ITOU, N, SATOH, H, OKABE, M

“…Using a real-time RT-PCR method, we analyzed the expression of e1a2 BCR-ABL mRNA in bone marrow samples from 13 patients with e1a2 BCR-ABL-positive acute…”
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Management of alloimmune thrombocytopenia by Kanhai, H. H. H., Porcelijn, L., Engelfriet, C. P., Reesink, H. W., Panzer, S., Ulm, B., Goldman, M., Bonacossa, I., Richard, L., David, M., Taaning, E., Hedegaard, M., Kaplan, C., Kiefel, V., Meyer, O., Salama, A., Morelati, F., Greppi, N., Marconi, M., Tassis, B., Tsuno, N. H., Takahashi, K., Oepkes, D., Kanhai, H., Osnes, L. T. N., Husebekk, A., Killie, M. K., Kjeldsen-Kragh, J., Zupanska, B., Muñiz-Diaz, E., Nogués, N., Parra, J., Urbaniak, S. J., Cameron, A.

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Cytokine-mediated regulation of CXCR4 expression in human neutrophils by Nagase, Hiroyuki, Miyamasu, Misato, Yamaguchi, Masao, Imanishi, Masako, Tsuno, Nelson H., Matsushima, Kouji, Yamamoto, Kazuhiko, Morita, Yutaka, Hirai, Koichi

“…Several lines of evidence have suggested that a CXC chemokine receptor 4 (CXCR4)/stromal cell‐derived factor‐1 [SDF‐1; CXC chemokine ligand 12 (CXCL12)] pair…”
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Laminin mediates tethering and spreading of colon cancer cells in physiological shear flow by KITAYAMA, J, NAGAWA, H, TSUNO, N, OSADA, T, HATANO, K, SUNAMI, E, SAITO, H, MUTO, T

“…Under the physiological shear condition, cultured colon cancer cells bound to laminin (LM), but not to fibronectin or vitronectin. Most of the tethered cells…”
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A study of dendritic and endothelial cell interactions in colon cancer in a cell line and small mammal model by Yoneyama, S, Okaji, Y, Tsuno, N.H, Kawai, K, Yamashita, H, Tsuchiya, T, Yamada, J, Sunami, E, Osada, T, Kitayama, J, Takahashi, K, Nagawa, H

“…Abstract Aim Historically, cancer therapy directly targeting tumor cells have yielded suboptimal clinical results, and therefore anti-angiogenic therapy that…”
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Spatial organization of EEG activity from alertness to sleep stage 2 in old and younger subjects by TSUNO, N., SHIGETA, M., HYOKI, K., KINOSHITA, T., USHIJIMA, S., FABER, P. L., LEHMANN, D.

“…In order to elucidate brain mechanisms that contribute to the increased tendency for vigilance dysregulation in the elderly, we examined the spatial…”
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Epigallocatechin gallate induces apoptosis of monocytes by Kawai, Kazushige, Tsuno, Nelson H., Kitayama, Joji, Okaji, Yurai, Yazawa, Kentaro, Asakage, Masahiro, Sasaki, Shin, Watanabe, Toshiaki, Takahashi, Koki, Nagawa, Hirokazu

“…Monocytes are the main effector cells of the immune system, and the regulation of their survival and apoptosis is essential for monocyte-involved immune…”
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Sleep and depression by TSUNO, Norifumi, BESSET, Alain, RITCHIE, Karen

“…Of all the psychiatric disorders associated with insomnia, depression is the most common. It has been estimated that 90% of patients with depression complain…”
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