Search Results - "TSUKAMOTO, Goro"

Anti-VRE and Anti-MRSA Activities of New Quinolones and Their Synergism with Commercial Antibiotics. Part 2 by SAKAGAMI, YOSHIKAZU, KOMEMUSHI, SADAO, TSUKAMOTO, GORO, KONDO, HIROSATO, YOSHIKAWA, AKIKO, MURAOKA, OSAMU

“…Anti-VRE and anti-MRSA activities of new quinolone derivatives [The two quinolone derivatives are 8- [3- [(ethylamino) methyl] -1-pyrrodinyl] -7-fluoro-9, 1-…”
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Activities of Novel New Quinolone Compounds against Vancomycin-Resistant Enterococci and Methicillin-Resistant Staphylococcus aureus and Their Synergism with Several Antibiotics by SAKAGAMI, YOSHIKAZU, MURAOKA, OSAMU, TSUKAMOTO, GORO

“…The activities of three new quinolone compounds against vancomycin-resistant enterococci (VRE) and methicillin-resistant Staphylococcus aureus (MRSA) and their…”
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Synthesis and antibacterial activity of new tetracyclic quinolone antibacterials by Taguchi, Masahiro, Kondo, Hirosato, Inoue, Yoshimasa, Kawahata, Yoshihiro, Jinbo, Yoshikazu, Sakamoto, Fumio, Tsukamoto, Goro

“…A series of 8-substituted-9,1-(epoxymethano)-7-fluoro-5-oxo-5H- thiazolo[3,2-a]quinoline-4-carboxylic acids having a novel tetracyclic structure was…”
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Synthesis and antibacterial activity of a new series of tetracyclic pyridone carboxylic acids. 2 by Jinbo, Yoshikazu, Taguchi, Masahiro, Inoue, Yoshimasa, Kondo, Hirosato, Miyasaka, Tomohiro, Tsujishita, Hideki, Sakamoto, Fumio, Tsukamoto, Goro

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5-Methyl-2-oxo-1,3-dioxol-4-yl) methyl Thiamine Sulfide の合成と性状 by 内田, 哲郎, 塚本, 悟郎, 山本, 浩二, 亀谷, 俊一, 前川, 博史, 西口, 郁三

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A Facile Synthetic Approach to Labeled 4-Acetoxy-2-(4-methylphenyl)benzothiazole by HORI, Noriyuki, SEKO, Norihiko, TSUKAMOTO, Goro, YOSHINO, Kohichiro

“…To study the pharmacokinetics and metabolism of 4-acetoxy-2-(4-methylphenyl)benzothiazole (KB-2683), which has potential immunomodulating activity, a practical…”
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Synthesis and Platelet Aggregation Inhibitory Activity of Diphenylazole Derivatives. I. Thiazole and Imidazole Derivatives by SEKO, Norihiko, YOSHINO, Kohichiro, YOKOTA, Koichi, TSUKAMOTO, Goro

“…Diphenylimidazole and diphenylthiazole derivatives were synthesized and tested as inhibitors of platelet aggregation in in vitro experiments with the rabbit…”
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Novel disease-modifying antirheumatic drugs. I: Synthesis and antiarthritic activity of 2-(4-methylphenyl)benzothiazoles by HORI, N, TSUKAMOTO, G, IMAMURA, A, OHASHI, M, SAITO, T, YOSHINO, K

“…A series of 2-(4-methylphenyl)benzothiazoles was synthesized and evaluated using an adjuvant-induced arthritic rat model. This class of desired compounds…”
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Activities of Noval New Quinolone Compounds against Vancomycin-Resistant Enterococci and Methicillin-Resistant Staphylococcus aureus and Their Synergism with Several Antibiotics by SAKAGAMI, YOSHIKAZU, MURAOKA, OSAMU, TSUKAMOTO, GORO

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2-Oxo-1,3-dioxoles as specific substrates for measurement of arylesterase activity by KAWAI, H, SAKAMOTO, F, TAGUCHI, M, KITAMURA, M, SOTOMUA, M, TSUKAMOTO, G

“…Various 4-arylthiomethyl-2-oxo-1,3-dioxole derivatives IIIa-o were synthesized. Their hydrolysis rates by arylesterase (EC 3.1.1.2) and cholinesterase (EC…”
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1H- and 13C-nuclear magneticresonance spectra of rifampicin and 3-((dimethylhydrazono)methyl)rifamycin SV.thylhydrazono)methyl)rifamycin SV by TAGUCHI, MASAHIRO, YAMANE, YUKINOBU, AIKAWA, NORIO, TSUKAMOTO, GORO

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Studies on Prodrugs. II. Preparation and Characterization of (5-Substituted 2-Oxo-1, 3-dioxolen-4-yl) methyl Esters of Ampicillin by SAKAMOTO, FUMIO, IKEDA, SHOJI, TSUKAMOTO, GORO

“…(5-Substituted 2-oxo-1, 3-dioxolen-4-yl) methyl esters were designed as a new type of ampicillin prodrug. These esters were prepared and confirmed to produce…”
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Benzylpiperazine Derivatives. III. Quantitative Structure-Cerebral Vasodilating Activity Relationships of 1-Benzyl-4- (3-hydroxy-3-phenylpentyl) piperazine Derivatives by OHTAKA, HIROSHI, TSUKAMOTO, GORO

“…Quantitative structure-cerebral vasodilating activity relationships of 1-benzyl-4- (3-hydroxy-3-phenylpropyl) piperazines were examined. The analyses indicate…”
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Benzylpiperazine Derivatives. V. Quantitative Structure-Activity Relationships of 1-Benzyl-4-diphenylmethylpiperazine Derivatives for Cerebral Vasodilating Activity by OHTAKA, HIROSHI, TSUKAMOTO, GORO

“…The quantitative structure-activity relationships of 1-benzyl-4-diphenylmethylpiperazines for cerebral vasodilating activity and duration of action were…”
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Synthesis of antimicrobial agents. II. Syntheses and antibacterial activities of optically active 7-(3-hydroxypyrrolidin-1-yl)quinolones by Uno, Toshio, Iuch, Koji, Kawahata, Yoshihiro, Tsukamoto, Goro

“…Two optically active isomers of 1‐ethyl‐6,8‐difluoro‐1,4‐dihydro‐7‐(3‐hydroxypyrrolidin‐1‐yl)‐4‐oxoquinoline‐3‐carboxylic acid (10) were prepared. One of the…”
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Studies on Prodrugs. IV. Preparation and Characterization of N-(5-Substituted 2-oxo-1, 3-dioxol-4-yl) methyl Norfloxacin by SAKAMOTO, FUMIO, IKEDA, SHOJI, KONDO, HIROSATO, TSUKAMOTO, GORO

“…As a new type of norfloxacin (NFLX) prodrug, N-(5-substituted 2-oxo-1, 3-dioxol-4-yl) methyl NFLXs were designed. These N-masked NFLXs were prepared and…”
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Organic phosphorus compounds. IV. Asymmetric 4-(Benzothiazol-2-yl)benzyophosphonates as potent calcium antagonistic vasodilators by YOSHINO, Kohichiro, GOTO, Katsumi, KOHNO, Toshihiko, MORITA, Tominori, TSUKAMOTO, Goro

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Benzylpiperazine Derivatives. IV. Syntheses and Cerebral Vasodilating Activities of 1-Benzyl-4-diphenylmethyl-piperazine Derivatives by OHTAKA, HIROSHI, KANAZAWA, TOSHIRO, ITO, KEIZO, TSUKAMOTO, GORO

“…A series of 1-benzyl-4-diphenylmethylpiperazines was prepared and tested for cerebral vasodilating activity. Among the compounds with stronger potency and…”
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A Novel Synthetic Method for Penicillanic Acid Derivatives by Electroreduction by IKEDA, SHOJI, TSUKAMOTO, GORO, NISHIGUCHI, IKUZO, HIRASHIMA, TSUNEAKI

“…Electroreductive dehalogenation of 6-halopenicillanic acid derivatives was conveniently carried out to give the corresponding penicillanic acid derivatives,…”
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Benzylpiperazine derivatives. II. Syntheses and cerebral vasodilating activities of 1-((3-alkyl-3-hydroxy-3-phenyl)propyl)-4-benzylpiperazine derivatives by OHTAKA, HIROSHI, FUJIMOTO, YOSHIAKI, YOSHIDA, KENJI, KANAZAWA, TOSHIRO, ITO, KEIZO, TSUKAMOTO, GORO

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