Search Results - "TSUJI, Keiko"

The dawn of pirna research in various neuronal disorders by Wakisaka, Keiko Tsuji, Imai, Yuzuru

“…Small non-coding PIWI-interacting RNAs (piRNAs) silence the expression of transposable elementsof eukaryotic genomes in germline cells. Additionally, piRNAs…”
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Decreased Memory and Learning Ability Mediated by Bmal1/M1 Macrophages/Angptl2/Inflammatory Cytokine Pathway in Mice Exposed to Long-Term Blue Light Irradiation by Hiramoto, Keiichi, Kubo, Sayaka, Tsuji, Keiko, Sugiyama, Daijiro, Hamano, Hideo

“…Humans are persistently exposed to massive amounts of blue light via sunlight, computers, smartphones, and similar devices. Although the positive and negative…”
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Bacillus coagulans (species of lactic acid-forming Bacillus bacteria) ameliorates azoxymethane and dextran sodium sulfate-induced colon cancer in mice by Hiramoto, Keiichi, Kubo, Sayaka, Tsuji, Keiko, Sugiyama, Daijiro, Iizuka, Yasutaka, Hamano, Hideo

“…[Display omitted] •Bacillus coagulans significantly ameliorated AOM+DSS-induced colon cancer in mice.•Bacillus coagulans altered expressions of several cell…”
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Sex Differences and Bmal1/Acetylcholine- or Bmal1/Noradrenaline-Mediated Effects of Blue Light Irradiation on Dextran-Sodium-Sulfate-Induced Ulcerative Colitis Model Mice by Hiramoto, Keiichi, Kubo, Sayaka, Tsuji, Keiko, Sugiyama, Daijiro, Hamano, Hideo

“…Humans are exposed to significant amounts of blue light from computers and smartphones. However, the effects of blue light on ulcerative colitis remain…”
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Induction of Skin Cancer by Long-Term Blue Light Irradiation by Hiramoto, Keiichi, Kubo, Sayaka, Tsuji, Keiko, Sugiyama, Daijiro, Hamano, Hideo

“…Presently, people are not only exposed to sunlight but also to a large amount of blue light from personal computers and smartphones. This blue light has…”
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Novel roles of Drosophila FUS and Aub responsible for piRNA biogenesis in neuronal disorders by Wakisaka, Keiko Tsuji, Tanaka, Ryo, Hirashima, Tomoki, Muraoka, Yuuka, Azuma, Yumiko, Yoshida, Hideki, Tokuda, Takahiko, Asada, Satoshi, Suda, Kojiro, Ichiyanagi, Kenji, Ohno, Seiko, Itoh, Masanobu, Yamaguchi, Masamitsu

“…•Aub overexpression enhanced mobility defects induced by the knockdown of Caz.•Caz plays a role in pre-piRNA production.•Knockdown of Caz produced abnormal…”
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Periprocedural and 30-day outcomes of robotic-assisted percutaneous coronary intervention used in the intravascular imaging guidance by Koeda, Yorihiko, Ishida, Masaru, Sasaki, Koto, Kikuchi, Sayaka, Yamaya, Shohei, Tsuji, Keiko, Ishisone, Takenori, Goto, Iwao, Kimura, Takumi, Shimoda, Yudai, Doi, Akio, Morino, Yoshihiro

“…In recent years, there have been several reports on robotic-assisted percutaneous coronary intervention (R-PCI), but few studies have been conducted on R-PCI…”
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The Effect of Bacillus coagulans Induced Interactions among Intestinal Bacteria, Metabolites, and Inflammatory Molecules in Improving Natural Skin Aging by Hiramoto, Keiichi, Kubo, Sayaka, Tsuji, Keiko, Sugiyama, Daijiro, Iizuka, Yasutaka, Hamano, Hideo

“…Background: Lactic acid bacteria consumption serves several health benefits to humans. However, their effect on natural skin aging is still unclear. Methods:…”
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A trafficking-deficient KCNQ1 mutation, T587M, causes a severe phenotype of long QT syndrome by interfering with intracellular hERG transport by Wu, Jie, Sakaguchi, Tomoko, Takenaka, Kotoe, Toyoda, Futoshi, Tsuji, Keiko, Matsuura, Hiroshi, Horie, Minoru

“…•KCNQ1 mutation T587M is correlated with severe phenotypes of long QT syndrome.•However, functional analysis of IKs with the KCNQ1-T587M shows a mild…”
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A Novel SCN5A Gain-of-Function Mutation M1875T Associated With Familial Atrial Fibrillation by Makiyama, Takeru, MD, PhD, Akao, Masaharu, MD, PhD, Shizuta, Satoshi, MD, Doi, Takahiro, MD, Nishiyama, Kei, MD, Oka, Yuko, MD, Ohno, Seiko, MD, PhD, Nishio, Yukiko, MD, Tsuji, Keiko, MS, Itoh, Hideki, MD, PhD, Kimura, Takeshi, MD, PhD, Kita, Toru, MD, PhD, Horie, Minoru, MD, PhD

“…Objectives This study describes a novel heterozygous gain-of-function mutation in the cardiac sodium (Na+ ) channel gene, SCN5A , identified in a Japanese…”
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Prevalence, clinical characteristics, and impact of active cancer in patients with acute myocardial infarction: data from an all-comer registry by Tosaka, Kengo, Ishida, Masaru, Tsuji, Keiko, Kanehama, Nozomu, Koeda, Yorihiko, Niiyama, Masanobu, Ishikawa, Yu, Shimoda, Yudai, Kimura, Takumi, Fusazaki, Tetsuya, Takahashi, Fumiaki, Itoh, Tomonori, Morino, Yoshihiro

“…•Active cancer prevalence was higher in acute myocardial infarction (AMI) patients than in the general population•Active cancer was associated with a higher…”
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Diversity of P- element piRNA production among M' and Q strains and its association with P-M hybrid dysgenesis in Drosophila melanogaster by Wakisaka, Keiko Tsuji, Ichiyanagi, Kenji, Ohno, Seiko, Itoh, Masanobu

“…Transposition of elements in the genome causes P-M hybrid dysgenesis in . For the P strain, the P-M phenotypes are associated with the ability to express a…”
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Association of zygotic piRNAs derived from paternal P elements with hybrid dysgenesis in Drosophila melanogaster by Wakisaka, Keiko Tsuji, Ichiyanagi, Kenji, Ohno, Seiko, Itoh, Masanobu

“…-element transposition in the genome causes P-M hybrid dysgenesis in . Maternally deposited piRNAs suppress -element transposition in the progeny, linking them…”
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Identification and functional characterization of KCNQ1 mutations around the exon 7–intron 7 junction affecting the splicing process by Tsuji–Wakisaka, Keiko, Akao, Masaharu, Ishii, Takahiro M., Ashihara, Takashi, Makiyama, Takeru, Ohno, Seiko, Toyoda, Futoshi, Dochi, Kenichi, Matsuura, Hiroshi, Horie, Minoru

“…Background. KCNQ1 gene encodes the delayed rectifier K + channel in cardiac muscle, and its mutations cause long QT syndrome type 1 (LQT1). Especially…”
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Immunomodulating effect of vitamin D3 derivatives on type-1 cellular immunity by IMAZEKI, Ikuo, MATSUZAKI, Junko, TSUJI, Keiko, NISHIMURA, Takashi

“…1α,25-dihydroxyvitamin D3 [Calcitriol or 1,25(OH)2D3] is an important active metabolite involved in multiple functions but its calcemic effect in vivo limits…”
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N- and C-terminal KCNE1 mutations cause distinct phenotypes of long QT syndrome by Ohno, Seiko, MD, Zankov, Dimitar P., MD, Yoshida, Hidetada, MD, PhD, Tsuji, Keiko, MS, Makiyama, Takeru, MD, Itoh, Hideki, MD, PhD, Akao, Masaharu, MD, PhD, Hancox, Jules C., PhD, Kita, Toru, MD, PhD, Horie, Minoru, MD, PhD

“…Background Long QT syndromes (LQTS) are inherited diseases involving mutations to genes encoding a number of cardiac ion channels and a membrane adaptor…”
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Mutation Analysis of the Glycerol-3 Phosphate Dehydrogenase-1 Like (GPD1L) Gene in Japanese Patients With Brugada Syndrome by Makiyama, Takeru, Akao, Masaharu, Haruna, Yoshisumi, Tsuji, Keiko, Doi, Takahiro, Ohno, Seiko, Nishio, Yukiko, Kita, Toru, Horie, Minoru

“…Brugada syndrome is an inherited arrhythmic disorder, and mutations in the SCN5A gene, encoding cardiac sodium channels, are identified in approximately 15% of…”
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Adrenergic regulation of the rapid component of delayed rectifier K+ current: Implications for arrhythmogenesis in LQT2 patients by Zankov, Dimitar P., MD, PhD, Yoshida, Hidetada, MD, PhD, Tsuji, Keiko, MS, Toyoda, Futoshi, PhD, Ding, Wei-Guang, MD, PhD, Matsuura, Hiroshi, MD, PhD, Horie, Minoru, MD, PhD

“…Background KCNH2 gene mutations disrupting rapid component of IK (IKr ) underlie type 2 congenital long QT syndrome (LQT2). Startled auditory stimuli are…”
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Molecular Characterization of Heat Shock-Like Factor Encoded on the Human Y Chromosome, and Implications for Male Infertility by SHINKA, Toshikatstu, SATO, Yoko, CHEN, Gang, NARODA, Takushi, KINOSHITA, Keigo, UNEMI, Yukiko, TSUJI, Keiko, TOIDA, Kazunori, IWAMOTO, Teruaki, NAKAHORI, Yutaka

“…Azoospermia and oligospermia are major causes of male infertility. Some genes located on the Y chromosome are suggested as candidates. Recently, HSFY, which is…”
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Age- and Genotype-Specific Triggers for Life-Threatening Arrhythmia in the Genotyped Long QT Syndrome by SAKAGUCHI, TOMOKO, SHIMIZU, WATARU, ITOH, HIDEKI, NODA, TAKASHI, MIYAMOTO, YOSHIHIRO, NAGAOKA, IORI, OKA, YUKO, ASHIHARA, TAKASHI, ITO, MAKOTO, TSUJI, KEIKO, OHNO, SEIKO, MAKIYAMA, TAKERU, KAMAKURA, SHIRO, HORIE, MINORU

“…Introduction: Patients with long QT syndrome (LQTS) become symptomatic in adolescence, but some become at age of ≥20 years. Since it remains unknown whether…”
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