Search Results - "TSUGAWA, Koichiro"
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A multi-national, randomised, open-label, parallel, phase III non-inferiority study comparing NK105 and paclitaxel in metastatic or recurrent breast cancer patients
Published in British journal of cancer (05-03-2019)“…Background NK105 is a novel nanoparticle drug delivery formulation that encapsulates paclitaxel (PTX) in polymeric micelles. We conducted an open-label phase…”
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A Genome-Wide Association Study Identifies Five Novel Genetic Markers for Trastuzumab-Induced Cardiotoxicity in Japanese Population
Published in Biological & pharmaceutical bulletin (01-12-2019)“…Trastuzumab has been administered to patients with human epidermal growth factor receptor 2 (HER2)-positive cancer, however, the cardiotoxicity is identified…”
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Subgroup analysis of Japanese patients in a Phase 3 study of atezolizumab in advanced triple-negative breast cancer (IMpassion130)
Published in Japanese journal of clinical oncology (27-12-2019)“…In the randomised Phase 3 IMpassion130 trial, atezolizumab combined with nab-paclitaxel (atezo + nab-P) in 902 patients with triple-negative breast cancer…”
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Pertuzumab retreatment for HER2‐positive advanced breast cancer: A randomized, open‐label phase III study (PRECIOUS)
Published in Cancer science (01-09-2022)“…No standard options existed for human epidermal growth factor receptor 2 (HER2)‐positive advanced breast cancer that progresses after second‐line trastuzumab…”
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Validation of the predictive accuracy of health-state utility values based on the Lloyd model for metastatic or recurrent breast cancer in Japan
Published in BMJ open (01-12-2021)“…IntroductionAlthough there is a lack of data on health-state utility values (HSUVs) for calculating quality-adjusted life-years in Japan, cost–utility analysis…”
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Risk Factors for Ipsilateral Breast Tumor Recurrence in Triple-Negative or HER2-Positive Breast Cancer Patients Who Achieve a Pathologic Complete Response After Neoadjuvant Chemotherapy
Published in Annals of surgical oncology (01-05-2021)“…Background Attention has been focused on attempts to eliminate breast surgery for breast cancer patients who achieve a pathologic complete response after…”
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Grading System to Categorize Breast MRI in BI-RADS 5th Edition: A Multivariate Study of Breast Mass Descriptors in Terms of Probability of Malignancy
Published in American journal of roentgenology (1976) (01-03-2018)“…The purpose of this study is to analyze the association between the probability of malignancy and breast mass descriptors in the BI-RADS 5th edition and to…”
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Replication Study for the Association of Five SNPs Identified by GWAS and Trastuzumab-Induced Cardiotoxicity in Japanese and Singaporean Cohorts
Published in Biological & pharmaceutical bulletin (01-08-2022)“…Trastuzumab (herceptin) is an effective drug for human epidermal growth factor receptor type 2 (HER2)-positive cancer. However, cardiotoxicity remains a…”
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Changes in Health State Utility Values in Japanese Patients with End-Stage Breast Cancer
Published in Current oncology (Toronto) (18-10-2021)“…We aimed to determine the dynamic trends in health state utility values (HSUVs) in patients with end-stage breast cancer. We selected 181 patients comprising…”
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Japan Society of Clinical Oncology Clinical Practice Guidelines 2017 for fertility preservation in childhood, adolescent, and young adult cancer patients: part 1
Published in International journal of clinical oncology (01-02-2022)“…In 2017, the Japan Society of Clinical Oncology (JSCO) published the JSCO Clinical Practice Guidelines 2017 for Fertility Preservation in Childhood,…”
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Japan Society of Clinical Oncology Clinical Practice Guidelines 2017 for fertility preservation in childhood, adolescent, and young adult cancer patients: part 2
Published in International journal of clinical oncology (01-02-2022)“…The Japan Society of Clinical Oncology (JSCO) published the “JSCO Clinical Practice Guidelines 2017 for Fertility Preservation in Childhood, Adolescent, and…”
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Young adult breast cancer patients have a poor prognosis independent of prognostic clinicopathological factors: a study from the Japanese Breast Cancer Registry
Published in Breast cancer research and treatment (01-11-2016)“…Purpose The aim of this study was to investigate whether young age at onset of breast cancer is an independent prognostic factor in patients from the Japanese…”
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Genomic profiling reveals heterogeneous populations of ductal carcinoma in situ of the breast
Published in Communications biology (01-04-2021)“…In a substantial number of patients, ductal carcinoma in situ (DCIS) of the breast will never progress to invasive ductal carcinoma, and these patients are…”
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LSD1 overexpression is associated with poor prognosis in basal-like breast cancer, and sensitivity to PARP inhibition
Published in PloS one (13-02-2015)“…LSD1, a lysine-specific histone demethylase, is overexpressed in several types of cancers and linked to poor outcomes. In breast cancer, the significance of…”
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One-step Nucleic Acid Amplification for Intraoperative Detection of Lymph Node Metastasis in Breast Cancer Patients
Published in Clinical cancer research (15-08-2007)“…Purpose: Detection of sentinel lymph node (SLN) metastasis in breast cancer patients has conventionally been determined by intraoperative histopathologic…”
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Semibulk RNA-seq analysis as a convenient method for measuring gene expression statuses in a local cellular environment
Published in Scientific reports (12-09-2022)“…When biologically interpretation of the data obtained from the single-cell RNA sequencing (scRNA-seq) analysis is attempted, additional information on the…”
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Role of Postmastectomy Radiotherapy After Neoadjuvant Chemotherapy in Breast Cancer Patients: A Study from the Japanese Breast Cancer Registry
Published in Annals of surgical oncology (01-08-2019)“…Background The role of postmastectomy radiotherapy (PMRT) in breast cancer patients receiving neoadjuvant chemotherapy (NAC) is controversial. We aimed to…”
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A Japanese nationwide survey on the cryopreservation of embryos, oocytes and ovarian tissue for cancer patients
Published in The journal of obstetrics and gynaecology research (01-10-2019)“…Aim The survival rates of cancer patients have greatly improved owing to the advances in oncology. The preservation of fertility in cancer patients is an…”
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Molecular Detection of Lymph Node Metastases in Breast Cancer Patients: Results of a Multicenter Trial Using the One-Step Nucleic Acid Amplification Assay
Published in Clinical cancer research (15-04-2009)“…Purpose: Accurate assessment of metastasis in sentinel lymph nodes (SLN) of breast cancer is important but involves a heavy workload for the pathologist. We…”
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Comparison of diagnostic precision for bone metastasis of primary breast cancer between BONENAVI version 1 and BONENAVI version 2
Published in Nuclear medicine communications (01-11-2019)“…OBJECTIVEThe aim of this study was to compare the diagnostic precision of bone scintigraphy with BONENAVI version 1 and BONENAVI version 2 in bone metastasis…”
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