Search Results - "TSOPORIS, James N"
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Protective function of DJ-1/PARK7 in lipopolysaccharide and ventilator-induced acute lung injury
Published in Redox biology (01-01-2021)“…Oxidative stress is considered one of the early underlying contributors of acute lung injury (ALI) and ventilator-induced lung injury (VILI). DJ-1, also known…”
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A Brief Overview of Cholinergic and Phosphodiesterase-5 Inhibitors in Diabetic Bladder Dysfunction
Published in International journal of molecular sciences (01-10-2024)“…Diabetic bladder dysfunction (DBD) comprises a wide spectrum of lower urinary tract symptoms that impact diabetic patients' lives, including urinary frequency,…”
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Tiny Guides, Big Impact: Focus on the Opportunities and Challenges of miR-Based Treatments for ARDS
Published in International journal of molecular sciences (28-02-2024)“…Acute Respiratory Distress Syndrome (ARDS) is characterized by lung inflammation and increased membrane permeability, which represents the leading cause of…”
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Cytoprotective Mechanisms of DJ-1: Implications in Cardiac Pathophysiology
Published in Molecules (Basel, Switzerland) (22-06-2021)“…DJ-1 was originally identified as an oncogene product while mutations of the gene encoding DJ-1/PARK7 were later associated with a recessive form of…”
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Circulating Ligands of the Receptor for Advanced Glycation End Products and the Soluble Form of the Receptor Modulate Cardiovascular Cell Apoptosis in Diabetes
Published in Molecules (Basel, Switzerland) (10-11-2020)“…We determined whether plasma concentrations of the receptor for advanced glycation end products (RAGE) and the soluble (s) form of RAGE (sRAGE) in healthy…”
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S100A1 is released from ischemic cardiomyocytes and signals myocardial damage via Toll‐like receptor 4
Published in EMBO molecular medicine (01-06-2014)“…Members of the S100 protein family have been reported to function as endogenous danger signals (alarmins) playing an active role in tissue inflammation and…”
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Cardiac Overexpression of S100A6 Attenuates Cardiomyocyte Apoptosis and Reduces Infarct Size After Myocardial Ischemia‐Reperfusion
Published in Journal of the American Heart Association (01-02-2017)“…Background Cardiomyocyte‐specific transgenic mice overexpressing S100A6, a member of the family of EF‐hand calcium‐binding proteins, develop less cardiac…”
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Differential Expression of Circulating Damage-Associated Molecular Patterns in Patients with Coronary Artery Ectasia
Published in Biomolecules (Basel, Switzerland) (01-01-2024)“…Coronary artery ectasia (CAE) is defined as abnormal dilation of a coronary artery with a diameter exceeding that of adjacent normal arterial segment by >1.5…”
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Differential Regulation of Circulating Soluble Receptor for Advanced Glycation End Products (sRAGEs) and Its Ligands S100A8/A9 Four Weeks Post an Exercise Intervention in a Cohort of Young Army Recruits
Published in Biomolecules (Basel, Switzerland) (13-09-2021)“…Apart from its beneficial effects on cardiovascular risk factors, an anti-inflammatory effect of exercise is strongly implicated. Yet, data regarding the…”
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DJ-1 Deficiency Protects against Sepsis-Induced Myocardial Depression
Published in Antioxidants (24-02-2023)“…Oxidative stress is considered one of the early underlying contributors of sepsis-induced myocardial depression. DJ-1, also known as PARK7, has a…”
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Emergent Inflammatory Markers and Echocardiographic Indices in Patients with Bronchial Asthma
Published in Biomolecules (Basel, Switzerland) (01-06-2023)“…Asthma is a heterogeneous disease, characterized by chronic inflammation and oxidative stress of the airways. Several inflammatory pathways including…”
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Correction: Let-7, Mir-98 and Mir-181 as Biomarkers for Cancer and Schizophrenia
Published in PloS one (12-08-2015)Get full text
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Beneficial effects of long-term use of the antioxidant probucol in heart failure in the rat
Published in Circulation (New York, N.Y.) (28-05-2002)“…Congestive heart failure (CHF) is a disease that is characterized by progressive left ventricular (LV) dysfunction and dilatation. Oxidative stress is thought…”
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Mesenchymal stromal (stem) cell therapy modulates miR-193b-5p expression to attenuate sepsis-induced acute lung injury
Published in The European respiratory journal (01-01-2022)“…Although mesenchymal stromal (stem) cell (MSC) administration attenuates sepsis-induced lung injury in pre-clinical models, the mechanism(s) of action and host…”
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The role of oral antioxidants in the improvement of sperm parameters in infertile men
Published in World journal of urology (05-02-2024)“…Purpose A variety of pathologic conditions may increase oxidative stress in semen resulting in structural modifications to spermozoa’s plasma membrane that…”
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Emerging markers of inflammation and oxidative stress as potential predictors of coronary artery disease
Published in International journal of cardiology (01-04-2023)“…The multi-ligand receptor for advanced glycation end products (RAGE) and its ligands AGEs and S100/calgranulin proteins are important mediators of inflammation…”
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Increased right atrial appendage apoptosis is associated with differential regulation of candidate MicroRNAs 1 and 133A in patients who developed atrial fibrillation after cardiac surgery
Published in Journal of molecular and cellular cardiology (01-08-2018)“…Atrial fibrillation (AF) following on-pump coronary artery bypass grafting (CABG) is a common condition associated with increased morbidity and mortality. We…”
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Long COVID and neuropsychiatric manifestations (Review)
Published in Experimental and therapeutic medicine (01-05-2022)“…There is accumulating evidence in the literature indicating that a number of patients with coronavirus disease 2019 (COVID-19) may experience a range of…”
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Toll-Like Receptors, Associated Biochemical Signaling Networks, and S100 Ligands
Published in Shock (Augusta, Ga.) (01-08-2021)“…Host cells recognize molecules that signal danger using pattern recognition receptors (PRRs). Toll-like receptors (TLRs) are the most studied class of PRRs and…”
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A longitudinal study of alterations of circulating DJ-1 and miR203a-3p in association to olanzapine medication in a sample of first episode patients with schizophrenia
Published in Journal of psychiatric research (01-02-2022)“…Among different proposed pathophysiological mechanisms, redox imbalance has been suggested to be a potential contributor in the pathogenesis of schizophrenia…”
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