Search Results - "TSAVACHIDOU, Dimitra"

Effects of Abiraterone Acetate on Androgen Signaling in Castrate-Resistant Prostate Cancer in Bone by EFSTATHIOU, Eleni, TITUS, Mark, TRONCOSO, Patricia, LOGOTHETIS, Christopher T, TSAVACHIDOU, Dimitra, TZELEPI, Vassiliki, SIJIN WEN, HOANG, Anh, MOLINA, Arturo, CHIEFFO, Nicole, SMITH, Lisa A, KARLOU, Maria

“…Persistent androgen signaling is implicated in castrate-resistant prostate cancer (CRPC) progression. This study aimed to evaluate androgen signaling in bone…”
Get full text

Dual inhibition of tumor energy pathway by 2-deoxyglucose and metformin is effective against a broad spectrum of preclinical cancer models by Cheong, Jae-Ho, Park, Eun Sung, Liang, Jiyong, Dennison, Jennifer B, Tsavachidou, Dimitra, Nguyen-Charles, Catherine, Wa Cheng, Kwai, Hall, Hassan, Zhang, Dong, Lu, Yiling, Ravoori, Murali, Kundra, Vikas, Ajani, Jaffer, Lee, Ju-Seog, Ki Hong, Waun, Mills, Gordon B

“…Tumor cell proliferation requires both growth signals and sufficient cellular bioenergetics. The AMP-activated protein kinase (AMPK) pathway seems dominant…”
Get full text

An efficient procedure for protein extraction from formalin-fixed, paraffin-embedded tissues for reverse phase protein arrays by Guo, Huifang, Liu, Wenbin, Ju, Zhenlin, Tamboli, Pheroze, Jonasch, Eric, Mills, Gordon B, Lu, Yiling, Hennessy, Bryan T, Tsavachidou, Dimitra

“…Protein extraction from formalin-fixed paraffin-embedded (FFPE) tissues is challenging due to extensive molecular crosslinking that occurs upon formalin…”
Get full text

Cytoplasmic Sequestration of p27 via AKT Phosphorylation in Renal Cell Carcinoma by Kim, Jinhee, Jonasch, Eric, Alexander, Angela, Short, John D, Cai, Shengli, Wen, Sijin, Tsavachidou, Dimitra, Tamboli, Pheroze, Czerniak, Bogdan A, Do, Kim Anh, Wu, Kevin J, Marlow, Laura A, Wood, Christopher G, Copland, John A, Walker, Cheryl Lyn

“…Purpose: p27 localization and expression has prognostic and predictive value in cancer. Little is known regarding expression patterns of p27 in renal cell…”
Get full text

Development and Validation of a Gamma Globin RT-Ddpcr Exploratory Biomarker for Sickle Cell Phase 1 Clinical Trial Fis 002-2020 by Roth, Mark, Yang, Jian, Tsavachidou, Dimitra, Davis, Darren W.

“…FTX-6058, a selective and potent binder of embryonic ectoderm development protein (EED), is being investigated in Sickle Cell Disease (SCD). In-vitro and…”
Get full text

Gene Array Analysis Reveals Changes in Peripheral Nervous System Gene Expression following Stimuli That Result in Reactivation of Latent Herpes Simplex Virus Type 1: Induction of Transcription Factor Bcl-3 by Tsavachidou, D, Podrzucki, W, Seykora, J, Berger, S L

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Abstract 1265: Sustained PI3-kinase signaling is mediated by ICOS, not CD28, for anti-tumor T-cell responses elicited by anti-CTLA-4 by Chen, Hong, Fu, Tihui, Tsavachidou, Dimitra, Wen, Sijin, Ng Tang, Derek, He, Qiuming, Sun, Jing Jing, Sharma, Padmanee

“…Abstract The generation of anti-tumor T-cell responses requires at least two distinct signals consisting of T-cell receptor signaling and CD28-costimulation to…”
Get full text

Selenium and Vitamin E: Cell Type– and Intervention-Specific Tissue Effects in Prostate Cancer by Tsavachidou, Dimitra, McDonnell, Timothy J., Wen, Sijin, Wang, Xuemei, Vakar-Lopez, Funda, Pisters, Louis L., Pettaway, Curtis A., Wood, Christopher G., Do, Kim-Anh, Thall, Peter F., Stephens, Clifton, Efstathiou, Eleni, Taylor, Robert, Menter, David G., Troncoso, Patricia, Lippman, Scott M., Logothetis, Christopher J., Kim, Jeri

“…Background Secondary analyses of two randomized, controlled phase III trials demonstrated that selenium and vitamin E could reduce prostate cancer incidence…”
Get full text

Abstract 1278: Determining the proteomic changes that define progressor and non-progressor clear cell renal cell carcinoma by Kurban, Ghada, Tsavachidou, Dimitra, Gallie, Brenda, Evans, Andrew, Finelli, Antonio, Jonasch, Eric, Jewett, Michael

“…Abstract Renal cell carcinoma (RCC) is the most common type of kidney cancer, is increasing in incidence and is the most lethal genitourinary cancer. Due to…”
Get full text

CD4 T cells require ICOS-mediated PI3K signaling to increase T-Bet expression in the setting of anti-CTLA-4 therapy by Chen, Hong, Fu, Tihui, Suh, Woong-Kyung, Tsavachidou, Dimitra, Wen, Sijin, Gao, Jianjun, Ng Tang, Derek, He, Qiuming, Sun, Jingjing, Sharma, Padmanee

“…The transcription factor T-bet controls the Th1 genetic program in T cells for effective antitumor responses. Anti-CTLA-4 immunotherapy elicits dramatic…”
Get more information

Surgical ischemia and detection of clear cell renal cell carcinoma biomarkers by Gedye, Craig, Kurban, Ghada, Gallie, Brenda L., Leveridge, Michael John, Musquera, Mireia, Morales, Carlos, Brooks, Samira A, Tsavachidou, Dimitra, Finelli, Antonio, Evans, Andrew, Jonasch, Eric, Rathmell, Kimryn, Jewett, Michael A.S.

“…Abstract only…”
Get full text

Abstract 4612: Cell-type dependent responses to selenium and knockdown of SBP2 by Li, Jin, Suraokar, Milind B., Tsavachidou, Dimitra, Menter, David G., Kim, Jeri

“…Abstract Selenium is a trace element essential for human health. Evidence from previous epidemiologic studies and clinical trials suggested that selenium is…”
Get full text

SPRY2 is an inhibitor of the Ras/extracellular signal-regulated kinase pathway in melanocytes and melanoma cells with wild-type BRAF but not with the V599E mutant by TSAVACHIDOU, Dimitra, COLEMAN, Mathew L, ATHANASIADIS, Galene, SHUIXING LI, LICHT, Jonathan D, OLSON, Michael F, WEBER, Barbara L

“…BRAF mutations result in constitutively active BRAF kinase activity and increased extracellular signal-regulated kinase (ERK) signaling and cell proliferation…”
Get full text

Glycogen metabolism provides nutritional support to renal cancer cells under conditions of stress and may serve as a marker of response to antiangiogenic therapy with bevacizumab by Tsavachidou, Dimitra, Li, Yang, Guo, Huifang, Liu, Wenbin, Jonasch, Eric, Tamboli, Pheroze, Mills, Gordon B.

“…Abstract Purpose: The clear cell type of renal cell carcinoma (ccRCC) derives its histologic appearance from accumulation of glycogen, but the functional…”
Get full text

Abstract 2696: Modulation of intracrine androgen signaling in bone metastatic castrate resistant prostate cancer (bmCRPC) by MDV3100 by Efstathiou, Eleni, Titus, Mark, Tsavachidou, Dimitra, Wen, Sijin, Hoang, Anh, Ashe, Robynne, Karlou, Maria, Berman, Craig, Troncoso, Patricia, Mohler, James, Logothetis, Christopher J.

“…Abstract Background Androgen signaling is a central driver in CRPC. We performed a study to determine the effect of the antiandrogen MDV 3100 on bone marrow…”
Get full text

Abstract A2: A Study of the effects of MDV3100 in the tumor microenvironment of bone metastatic castrate resistant prostate cancer (bmCRPC) by Efstathiou, Eleni, Troncoso, Patricia, Mohler, James, Logothetis, Christopher J., Titus, Mark, Tsavachidou, Dimitra, Wen, Sijin, Hoang, Anh, Ashe, Robynne, Karlou, Maria, Berman, Craig

“…Abstract Background: Androgen signaling remains a central driver in castrate-resistant prostate cancer. We performed a study to determine the effect of the…”
Get full text

The development of an efficient procedure for protein extraction from formalin fixed and paraffin embedded tissues and analysis of its application to reverse phase protein arrays by Guo, Huifang, Liu, Wenbin, Zhu, Zhenlin, Jonasch, Eric, Mills, Gordon B., Hennessy, Bryan, Lu, Yiling, Tsavachidou, Dimitra

“…Abstract Purpose: Formalin fixation coupled with paraffin embedding (FFPE) is the standard tissue fixation and storage method adopted by most health…”
Get full text

Dual inhibition of Tumor Energy Pathway by 2-deoxy glucose and metformin Is Effective Against a Broad Spectrum of Preclinical Cancer Models by Cheong, Jae-Ho, Park, Eun Sung, Liang, Jiyong, Dennison, Jennifer B, Tsavachidou, Dimitra, Nguyen-Charles, Catherine, Cheng, Kwai Wa, Hall, Hassan, Zhang, Dong, Lu, Yiling, Ravoori, Murali, Kundra, Vikas, Ajani, Jaffer, Lee, Ju-Seog, Hong, Waun Ki, Mills, Gordon B

“…Tumor cell proliferation requires both growth signals and sufficient cellular bioenergetics.The AMP-activated kinase (AMPK) pathway appears dominant over the…”
Get full text

Abstract LB-421: Characterization of castrate resistant prostate cancer treated with abiraterone acetate and prednisone by Efstathiou, Eleni, Titus, Mark, Tsavachidou, Dimitra, Tzelepi, Vassiliki, Wen, Sijin, Hoang, Anh, Molina, Arturo, Chieffo, Nicole, Smith, Lisa A., Smith, BS RN, Karlou, Maria Karlou, Troncoso, Patricia, Logothetis, Christopher J.

“…Abstract Background: Recent observations implicate persistent androgen signaling in metastatic castrate-resistant prostate cancer (mCRPC) progression…”
Get full text

Modeling and simulation of pathways in memopause by Tsavachidou, Dimitra, Liebman, Michael N

Get full text