Search Results - "TSAO, P. S"

Inflammation in subcutaneous adipose tissue: relationship to adipose cell size by McLaughlin, T, Deng, A, Yee, G, Lamendola, C, Reaven, G, Tsao, P. S, Cushman, S. W, Sherman, A

“…Aims/hypothesis Inflammation is associated with increased body mass and purportedly with increased size of adipose cells. We sought to determine whether…”
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Insulin resistance is associated with a modest increase in inflammation in subcutaneous adipose tissue of moderately obese women by McLaughlin, T, Deng, A, Gonzales, O, Aillaud, M, Yee, G, Lamendola, C, Abbasi, F, Connolly, A. J, Sherman, A, Cushman, S. W, Reaven, G, Tsao, P. S

“…Aims/hypothesis We have previously described differences in adipose cell size distribution and expression of genes related to adipocyte differentiation in…”
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Metformin treatment lowers asymmetric dimethylarginine concentrations in patients with type 2 diabetes by Asagami, T., Abbasi, F., Stuelinger, M., Lamendola, C., McLaughlin, T., Cooke, J.P., Reaven, G.M., Tsao, P.S.

“…This study was initiated to see if plasma asymmetric dimethylarginine (ADMA) concentrations decreased in hyperglycemic patients with type 2 diabetes following…”
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Novel mechanism for endothelial dysfunction dysregulation of dimethylarginine dimethylaminohydrolase by ITO, A, TSAO, P. S, ADIMOOLAM, S, KIMOTO, M, OGAWA, T, COOKE, J. P

“…Asymmetric dimethylarginine (ADMA) is an endogenous inhibitor of nitric oxide synthase (NOS). Plasma levels of ADMA are elevated in individuals with…”
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Asymmetric dimethylarginine (ADMA) : A novel risk factor for endothelial dysfunction : Its role in hypercholesterolemia by BÖGER, R. H, BODE-BÖGER, S. M, SZUBA, A, TSAO, P. S, CHAN, J. R, TANGPHAO, O, BLASCHKE, T. F, COOKE, J. P

“…Asymmetric dimethylarginine (ADMA) is an endogenous competitive inhibitor of nitric oxide (NO) synthase. Because endothelial NO elaboration is impaired in…”
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Enhanced endothelial adhesiveness in hypercholesterolemia is attenuated by L-arginine by TSAO, P. S, MCEVOY, L. M, DREXLER, H, BUTCHER, E. C, COOKE, J. P

“…We have shown that chronic administration of the nitric oxide (NO) precursor L-arginine normalizes NO-dependent vasodilation and markedly inhibits…”
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Time course of endothelial dysfunction and myocardial injury during myocardial ischemia and reperfusion in the cat by TSAO, P. S, AOKI, N, LEFER, D. J, JOHNSON, G. III, LEFER, A. M

“…Myocardial ischemia and reperfusion have been shown to impair coronary vasorelaxation to endothelium-dependent vasodilators. To examine the time course of this…”
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Fluid flow inhibits endothelial adhesiveness : Nitric oxide and transcriptional regulation of VCAM-1 by TSAO, P. S, BUITRAGO, R, CHAN, J. R, COOKE, J. P

“…In the arterial tree, regions exposed to reduced shear stress (low and/or disturbed flow) are predisposed to atherogenesis. Fluid flow is a potent stimulus for…”
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H19 Induces Abdominal Aortic Aneurysm Development and Progression by Li, Daniel Y, Busch, Albert, Jin, Hong, Chernogubova, Ekaterina, Pelisek, Jaroslav, Karlsson, Joakim, Sennblad, Bengt, Liu, Shengliang, Lao, Shen, Hofmann, Patrick, Bäcklund, Alexandra, Eken, Suzanne M, Roy, Joy, Eriksson, Per, Dacken, Brian, Ramanujam, Deepak, Dueck, Anne, Engelhardt, Stefan, Boon, Reinier A, Eckstein, Hans-Henning, Spin, Joshua M, Tsao, Philip S, Maegdefessel, Lars

“…BACKGROUND—Long noncoding RNAs (lncRNAs) have emerged as critical molecular regulators in various biological processes and diseases. Here we sought to identify…”
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Antibody to CD-18 exerts endothelial and cardiac protective effects in myocardial ischemia and reperfusion by XIN-LIANG MA, TSAO, P. S, LEFER, A. M

“…We studied the effects of MAbR15.7, an antibody directed against the common beta-chain (CD-18) of a family of neutrophil adherence glycoproteins, on…”
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Time course and mechanism of endothelial dysfunction in isolated ischemic- and hypoxic-perfused rat hearts by Tsao, P S, Lefer, A M

“…Isolated perfused rat hearts were subjected to global ischemia for 30 min followed by reperfusion for 2.5, 5, 10, or 20 min and then were tested for…”
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Nitric oxide regulates monocyte chemotactic protein-1 by TSAO, P. S, WANG, B.-Y, BUITRAGO, R, SHYY, J. Y.-J, COOKE, J. P

“…Monocyte chemotactic protein-1 (MCP-1) is a 76-amino-acid chemokine thought to be the major chemotactic factor for monocytes. We and others have demonstrated…”
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Asymmetric Dimethylarginine Increases Mononuclear Cell Adhesiveness in Hypercholesterolemic Humans by Chan, Jason R, Böger, Rainer H, Bode-Böger, Stefanie M, Tangphao, Oranee, Tsao, Philip S, Blaschke, Terrence F, Cooke, John P

“…ABSTRACTAsymmetric dimethylarginine (ADMA), an endogenous inhibitor of nitric oxide synthase, is elevated in hypercholesterolemia. This study was designed to…”
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Regression of atherosclerosis : Role of nitric oxide and apoptosis by WANG, B.-Y, HO, H.-K. V, LIN, P. S, SCHWARZACHER, S. P, POLLMAN, M. J, GIBBONS, G. H, TSAO, P. S, COOKE, J. P

“…We have recently found that administration of L-arginine to hypercholesterolemic rabbits induces regression of preexisting lesions. Others have previously…”
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Cytoprotective effects of nitric oxide by Cooke, J P, Tsao, P S

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MicroRNA-21 blocks abdominal aortic aneurysm development and nicotine-augmented expansion by Maegdefessel, Lars, Azuma, Junya, Toh, Ryuji, Deng, Alicia, Merk, Denis R, Raiesdana, Azad, Leeper, Nicholas J, Raaz, Uwe, Schoelmerich, Anke M, McConnell, Michael V, Dalman, Ronald L, Spin, Joshua M, Tsao, Philip S

“…Identification and treatment of abdominal aortic aneurysm (AAA) remains among the most prominent challenges in vascular medicine. MicroRNAs are crucial…”
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Dietary l-Arginine Supplementation Normalizes Platelet Aggregation in Hypercholesterolemic Humans by Wolf, Andreas, Zalpour, Christoff, Theilmeier, Gregor, Wang, Bing-yin, Ma, Adrian, Anderson, Barbara, Tsao, Philip S, Cooke, John P

“…Objectives. The present study was designed to test the hypothesis that long-term dietary supplementation with the nitric oxide precursor l-arginine would…”
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Cardioprotective effects of authentic nitric oxide in myocardial ischemia with reperfusion by Johnson, 3rd, G, Tsao, P S, Lefer, A M

“…The purpose of this study was to determine the effects of nitric oxide (NO), believed to be endothelium-derived relaxing factor on reperfusion injury after…”
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L-arginine attenuates platelet reactivity in hypercholesterolemic rabbits by TSAO, P. S, THEILMEIER, G, SINGER, A. H, LEUNG, L. L.-K, COOKE, J. P

“…Platelets are capable of producing nitric oxide (NO) through the L-arginine-NO synthase pathway. Acute exposure to supraphysiological concentrations of…”
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Exposure to shear stress alters endothelial adhesiveness : role of nitric oxide by TSAO, P. S, LEWIS, N. P, ALPERT, S, COOKE, J. P

“…Shear stress increases the release of nitric oxide (NO) by endothelial cells (ECs). We and others have provided evidence that endothelium-derived NO inhibits…”
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